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The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.

iPSCs - Novel Concepts, Volume 15 addresses how important induced pluripotent stems cells are and how can they can help treat certain diseases.

Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different disorders, such as liver disease, type-1 diabetes, Parkinson’s disease, macular degeneration of the retina and much more.

The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field.

  • Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics
  • Covers spinal cord injuries, type-1 diabetes, liver disease, Parkinson’s disease, graft vs. host disease, and much more
  • Contributed by world-renown experts in the field

1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Advances in Stem Cell Biology - p. iii 6. Copyright - p. iii 7. Dedication - p. iii 8. List of contributors - p. xv 9. About the editor - p. xix 10. Preface - p. xxiii 11. Chapter 1. Induced pluripotent stem cells: novel concepts for respiratory disease modeling - p. 1 12. Chapter 2. iPSC for modeling of metabolic and neurodegenerative disorders - p. 59 13. Chapter 3. Induced pluripotent stem cells for modeling open-angle glaucoma - p. 85 14. Chapter 4. Patient-specific induced pluripotent stem cells for understanding and assessing novel therapeutics for multisystem transthyretin amyloid disease - p. 105 15. Chapter 5. iPSCs for modeling choroideremia - p. 123 16. Chapter 6. Applications of human induced pluripotent stem cell and human embryonic stem cell models for substance use disorders: addiction and neurodevelopmental toxicity - p. 153 17. Chapter 7. Induced pluripotent stem cells for modeling cardiac sodium channelopathies - p. 179 18. Chapter 8. iPSCs for modeling Danon disease - p. 193 19. Chapter 9. Human-induced pluripotent stem cells for modeling of Niemann-Pick disease type C1 - p. 207 20. Chapter 10. iPSC-based modeling in psychiatric disorders: opportunities and challenges - p. 219 21. Chapter 11. Research applications of induced pluripotent stem cells for treatment and modeling of spinal cord injury - p. 245 22. Chapter 12. Functional outcomes of copy number variations of Chrna7 gene: current knowledge and new insight from induced pluripotent stem cells studies - p. 269 23. Index - p. 307

Descripcion
Descripción

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology.

iPSCs - Novel Concepts, Volume 15 addresses how important induced pluripotent stems cells are and how can they can help treat certain diseases.

Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different disorders, such as liver disease, type-1 diabetes, Parkinson’s disease, macular degeneration of the retina and much more.

The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field.

  • Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics
  • Covers spinal cord injuries, type-1 diabetes, liver disease, Parkinson’s disease, graft vs. host disease, and much more
  • Contributed by world-renown experts in the field

1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Advances in Stem Cell Biology - p. iii 6. Copyright - p. iii 7. Dedication - p. iii 8. List of contributors - p. xv 9. About the editor - p. xix 10. Preface - p. xxiii 11. Chapter 1. Induced pluripotent stem cells: novel concepts for respiratory disease modeling - p. 1 12. Chapter 2. iPSC for modeling of metabolic and neurodegenerative disorders - p. 59 13. Chapter 3. Induced pluripotent stem cells for modeling open-angle glaucoma - p. 85 14. Chapter 4. Patient-specific induced pluripotent stem cells for understanding and assessing novel therapeutics for multisystem transthyretin amyloid disease - p. 105 15. Chapter 5. iPSCs for modeling choroideremia - p. 123 16. Chapter 6. Applications of human induced pluripotent stem cell and human embryonic stem cell models for substance use disorders: addiction and neurodevelopmental toxicity - p. 153 17. Chapter 7. Induced pluripotent stem cells for modeling cardiac sodium channelopathies - p. 179 18. Chapter 8. iPSCs for modeling Danon disease - p. 193 19. Chapter 9. Human-induced pluripotent stem cells for modeling of Niemann-Pick disease type C1 - p. 207 20. Chapter 10. iPSC-based modeling in psychiatric disorders: opportunities and challenges - p. 219 21. Chapter 11. Research applications of induced pluripotent stem cells for treatment and modeling of spinal cord injury - p. 245 22. Chapter 12. Functional outcomes of copy number variations of Chrna7 gene: current knowledge and new insight from induced pluripotent stem cells studies - p. 269 23. Index - p. 307

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