A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Opioids, Volume 4 in the series, explores the molecular, cellular and systems in the brain responsible for opioid addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Opioids - p. iii 5. Copyright - p. iv 6. Preface - p. vii 7. Acknowledgments - p. ix 8. VOLUME FOUR. Opioids - p. 1 9. 1. Definitions - p. 2 10. 2. History of opioid use, misuse, and addiction - p. 3 11. 3. Medical use and behavioral effects - p. 9 12. 4. Pharmacokinetics - p. 12 13. 5. Addiction potential - p. 14 14. 6. Behavioral mechanism of action - p. 45 15. 7. Neurobiological effects - p. 98 16. Index - p. 401
A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Opioids, Volume 4 in the series, explores the molecular, cellular and systems in the brain responsible for opioid addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Opioids - p. iii 5. Copyright - p. iv 6. Preface - p. vii 7. Acknowledgments - p. ix 8. VOLUME FOUR. Opioids - p. 1 9. 1. Definitions - p. 2 10. 2. History of opioid use, misuse, and addiction - p. 3 11. 3. Medical use and behavioral effects - p. 9 12. 4. Pharmacokinetics - p. 12 13. 5. Addiction potential - p. 14 14. 6. Behavioral mechanism of action - p. 45 15. 7. Neurobiological effects - p. 98 16. Index - p. 401
