Organ Repair and Regeneration: Preserving Organs in the Regenerative Medicine Era encompasses updates on all organs, from the kidneys, to the lungs, liver, pancreas, intestines, and beyond. Chapters cover the pathophysiology of ischemia-reperfusion, repairing organs with MSC, repairing cardiac allografts in situ, and much more. The book conceptualizes the idea that the modern approach to organ preservation is ante literam, a form of organ repair and regeneration which, per se, is referred to as a field of health sciences under the umbrella of regenerative medicine. This book demonstrates the merging of regenerative medicine and organ transplantation.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contributors - p. ix 7. Foreword - p. xi 8. Preface - p. xii 9. Chapter 1. Ischemia-reperfusion injury - p. 1 10. Chapter 2. Machine perfusion for donor organ repair: from vision to everyday clinical practice - p. 43 11. Chapter 3. Assessing and reconditioning kidneys using normothermic machine perfusion - p. 75 12. Chapter 4. Autologous cells for renal allograft repair - p. 95 13. Chapter 5. Repairing organs with MSC - p. 115 14. Chapter 6. Resuscitation of the pancreas: whole organ and islet cell technologies into the machine era - p. 135 15. Chapter 7. Assessment of extended criteria liver grafts during machine perfusion. How far can we go? - p. 169 16. Chapter 8. RNA interference in organ transplantation: next-generation medicine? - p. 189 17. Chapter 9. Repairing cardiac allografts on ex situ perfusion devices - p. 213 18. Chapter 10. Repairing cardiac allografts in situ - p. 231 19. Chapter 11. Steatotic livers for transplantation: improving utilization of a prevalent resource through organ repair - p. 247 20. Chapter 12. Implementing the vision: the organ repair center - p. 257 21. Chapter 13. Mitochondria transplantation in organ damage and repair - p. 263 22. Chapter 14. How the transplant landscape is changing in the regenerative medicine era - p. 273 23. Index - p. 285
Organ Repair and Regeneration: Preserving Organs in the Regenerative Medicine Era encompasses updates on all organs, from the kidneys, to the lungs, liver, pancreas, intestines, and beyond. Chapters cover the pathophysiology of ischemia-reperfusion, repairing organs with MSC, repairing cardiac allografts in situ, and much more. The book conceptualizes the idea that the modern approach to organ preservation is ante literam, a form of organ repair and regeneration which, per se, is referred to as a field of health sciences under the umbrella of regenerative medicine. This book demonstrates the merging of regenerative medicine and organ transplantation.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contributors - p. ix 7. Foreword - p. xi 8. Preface - p. xii 9. Chapter 1. Ischemia-reperfusion injury - p. 1 10. Chapter 2. Machine perfusion for donor organ repair: from vision to everyday clinical practice - p. 43 11. Chapter 3. Assessing and reconditioning kidneys using normothermic machine perfusion - p. 75 12. Chapter 4. Autologous cells for renal allograft repair - p. 95 13. Chapter 5. Repairing organs with MSC - p. 115 14. Chapter 6. Resuscitation of the pancreas: whole organ and islet cell technologies into the machine era - p. 135 15. Chapter 7. Assessment of extended criteria liver grafts during machine perfusion. How far can we go? - p. 169 16. Chapter 8. RNA interference in organ transplantation: next-generation medicine? - p. 189 17. Chapter 9. Repairing cardiac allografts on ex situ perfusion devices - p. 213 18. Chapter 10. Repairing cardiac allografts in situ - p. 231 19. Chapter 11. Steatotic livers for transplantation: improving utilization of a prevalent resource through organ repair - p. 247 20. Chapter 12. Implementing the vision: the organ repair center - p. 257 21. Chapter 13. Mitochondria transplantation in organ damage and repair - p. 263 22. Chapter 14. How the transplant landscape is changing in the regenerative medicine era - p. 273 23. Index - p. 285