This issue of Clinics in Perinatology will carry the reader through the perinatal period and examine pain management throughout that continuum. Beginning with the genetics of obstetrical pain and opioid use in pregnancy, the discussion moves to the provision of anesthesia to the mother and fetus during fetal surgery – an area of intense concern and interest in many centers. There is an extensive discussion of both pharmacologic and non-pharmacologic management of pain during delivery. A discussion of regional anesthetic techniques is increasingly relevant in light of increasing evidence of adverse neurodevelopmental consequences of fetal exposure to general anesthetics and sedatives. Pain, its implications and management, are extensively covered including discussions of how to assess neonatal pain and how best to provide sedation and non-pharmacologic pain management, systemic pharmacologic, or regional techniques. Of particular interest are the reviews of the potential neurodevelopmental impact of both the treatment and the failure to adequately treat pain in the newborn. This topic is receiving an enormous amount of attention from all those who care for children as well as government and the media.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. Contents - p. 5 6. CME Accreditation Page and Author Disclosure - p. 8 7. Forthcoming Issues - p. 9 8. Painful Truths About Newborn Pain Management - p. 10 9. Pain Management in the Perinatal Period - p. 11 10. Chronic Opioid Use During Pregnancy - p. 12 11. Nonpharmacologic Labor Analgesia - p. 20 12. Combined Spinal-Epidural Versus Epidural Analgesia for Labor and Delivery - p. 28 13. The Association Between Epidural Labor Analgesia and Maternal Fever - p. 35 14. Anesthetic Management of External Cephalic Version - p. 43 15. Maternal Anesthesia for Fetal Surgery - p. 49 16. Fetal Anesthesia and Pain Management for Intrauterine Therapy - p. 56 17. Multimodal Postcesarean Delivery Analgesia - p. 63 18. Assessment of Pain in the Neonate - p. 71 19. Biological and Neurodevelopmental Implications of Neonatal Pain - p. 77 20. Nonpharmacological Management of Pain During Common Needle Puncture Procedures in Infants - p. 87 21. Management of Neonatal Abstinence Syndrome from Opioids - p. 96 22. Regional Anesthesia in Neonates and Infants - p. 103 23. Sedation and Analgesia to Facilitate Mechanical Ventilation - p. 111 24. Neurodevelopmental Implications of the Use of Sedation and Analgesia in Neonates - p. 123 25. Genetic Contributions to Labor Pain and Progress - p. 132 26. Index - p. 138
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This issue of Clinics in Perinatology will carry the reader through the perinatal period and examine pain management throughout that continuum. Beginning with the genetics of obstetrical pain and opioid use in pregnancy, the discussion moves to the provision of anesthesia to the mother and fetus during fetal surgery – an area of intense concern and interest in many centers. There is an extensive discussion of both pharmacologic and non-pharmacologic management of pain during delivery. A discussion of regional anesthetic techniques is increasingly relevant in light of increasing evidence of adverse neurodevelopmental consequences of fetal exposure to general anesthetics and sedatives. Pain, its implications and management, are extensively covered including discussions of how to assess neonatal pain and how best to provide sedation and non-pharmacologic pain management, systemic pharmacologic, or regional techniques. Of particular interest are the reviews of the potential neurodevelopmental impact of both the treatment and the failure to adequately treat pain in the newborn. This topic is receiving an enormous amount of attention from all those who care for children as well as government and the media.
1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. Contents - p. 5 6. CME Accreditation Page and Author Disclosure - p. 8 7. Forthcoming Issues - p. 9 8. Painful Truths About Newborn Pain Management - p. 10 9. Pain Management in the Perinatal Period - p. 11 10. Chronic Opioid Use During Pregnancy - p. 12 11. Nonpharmacologic Labor Analgesia - p. 20 12. Combined Spinal-Epidural Versus Epidural Analgesia for Labor and Delivery - p. 28 13. The Association Between Epidural Labor Analgesia and Maternal Fever - p. 35 14. Anesthetic Management of External Cephalic Version - p. 43 15. Maternal Anesthesia for Fetal Surgery - p. 49 16. Fetal Anesthesia and Pain Management for Intrauterine Therapy - p. 56 17. Multimodal Postcesarean Delivery Analgesia - p. 63 18. Assessment of Pain in the Neonate - p. 71 19. Biological and Neurodevelopmental Implications of Neonatal Pain - p. 77 20. Nonpharmacological Management of Pain During Common Needle Puncture Procedures in Infants - p. 87 21. Management of Neonatal Abstinence Syndrome from Opioids - p. 96 22. Regional Anesthesia in Neonates and Infants - p. 103 23. Sedation and Analgesia to Facilitate Mechanical Ventilation - p. 111 24. Neurodevelopmental Implications of the Use of Sedation and Analgesia in Neonates - p. 123 25. Genetic Contributions to Labor Pain and Progress - p. 132 26. Index - p. 138
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