Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides describes the procedures and protocols related to the modification of nucleosides, nucleotides and oligonucleotides via Pd-mediated cross-coupling processes. The book highlights the growing area of nucleic acid modification and how Pd-mediated coupling reactions can assist this development. Users will find key synthetic protocols for these reactions in this latest volume in the Latest Trends in Palladium Chemistry series. As most of the research in the field of antiviral agents has centered on the use of modified nucleosides that have exhibited promising activity, this book provides an up-to-date reference for both professionals in industry and other interested parties.
1. Chapter 8: Application of Water-Soluble Palladium-Catalyst Systems for Introduction of C–C Bonds in Nucleosides - p. 246 2. Chapter 9: Advances in the Application of Pd-Mediated Transformations in Nucleotides and Oligonucleotides - p. 268 3. Chapter 10: Nucleoside Modification Using Buchwald-Hartwig Amination Reactions - p. 293 4. Index - p. 335
Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides describes the procedures and protocols related to the modification of nucleosides, nucleotides and oligonucleotides via Pd-mediated cross-coupling processes. The book highlights the growing area of nucleic acid modification and how Pd-mediated coupling reactions can assist this development. Users will find key synthetic protocols for these reactions in this latest volume in the Latest Trends in Palladium Chemistry series. As most of the research in the field of antiviral agents has centered on the use of modified nucleosides that have exhibited promising activity, this book provides an up-to-date reference for both professionals in industry and other interested parties.
1. Chapter 8: Application of Water-Soluble Palladium-Catalyst Systems for Introduction of C–C Bonds in Nucleosides - p. 246 2. Chapter 9: Advances in the Application of Pd-Mediated Transformations in Nucleotides and Oligonucleotides - p. 268 3. Chapter 10: Nucleoside Modification Using Buchwald-Hartwig Amination Reactions - p. 293 4. Index - p. 335