Pathology of the Laboratory Rabbit serves as a “go to text for all pathologists working on laboratory rabbits in safety assessment studies. The book helps diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathology when assigning cause of death to these animals which are also kept as domestic pets. The book provides a comprehensive text on the spontaneous pathology seen in common laboratory rabbit strains. This is the first book collating information on all organ systems in these strains.
1. Introduction - p. xvii 2. Chapter 1. Study Design, Regulations, and Ethics in Rabbits for Biomedical Research - p. 1 3. Chapter 2. Future Use of Rabbits in Safety Assessment Regulatory Studies - p. 19 4. Chapter 3. Genetics of Rabbit Models - p. 33 5. Infectious Diseases of Young Rabbits - p. 43 6. Chapter 5. Clinical Examination and Routes of Administration - p. 103 7. Chapter 6. The Alimentary Tract and Exocrine Pancreas - p. 129 8. Chapter 7. The Hepatobiliary System - p. 151 9. Chapter 8. The Urinary System - p. 169 10. Chapter 9. The Nervous System - p. 181 11. Chapter 10. The Eye, Ear, and Ocular Adnexa - p. 205 12. Abstract - p. 205 13. 10.1 Introduction - p. 205 14. 10.2 The eye - p. 205 15. 10.3 Congenital lesions - p. 225 16. 10.4 Degenerative lesions - p. 227 17. 10.5 Inflammatory and vascular lesions - p. 240 18. 10.6 Hyperplastic lesions - p. 247 19. 10.7 Neoplastic lesions - p. 248 20. 10.8 Toxicologic lesions - p. 250 21. 10.9 Miscellaneous lesions and artifacts - p. 250 22. 10.10 The ear - p. 252 23. 10.11 Embryology, anatomy, and physiology - p. 253 24. 10.12 Congenital lesions - p. 261 25. 10.13 Degenerative lesions - p. 261 26. 10.14 Inflammatory and vascular lesions - p. 263 27. 10.15 Hyperplastic and neoplastic lesions - p. 263 28. 10.16 Toxicologic lesions - p. 264 29. 10.17 Artifacts and fixation - p. 264 30. Acknowledgment - p. 264 31. References - p. 264 32. Chapter 11. The Skeletal System and Teeth - p. 283 33. Chapter 12. The Integumentary System - p. 291 34. Chapter 13. The Soft Tissue and Skeletal Muscle - p. 313 35. Chapter 14. The Mammary Gland - p. 323 36. Chapter 15. The Respiratory Tract - p. 329 37. Chapter 16. The Haematopoietic and Lymphoid Systems - p. 349 38. Chapter 17. The Female Reproductive Tract - p. 363 39. Chapter 18. The Male Reproductive Tract - p. 385 40. Chapter 19. The Cardiovascular System - p. 413 41. Chapter 20. The Endocrine System - p. 431 42. Chapter 21. Clinical Pathology - p. 449 43. Index - p. 483
Pathology of the Laboratory Rabbit serves as a “go to text for all pathologists working on laboratory rabbits in safety assessment studies. The book helps diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathology when assigning cause of death to these animals which are also kept as domestic pets. The book provides a comprehensive text on the spontaneous pathology seen in common laboratory rabbit strains. This is the first book collating information on all organ systems in these strains.
1. Introduction - p. xvii 2. Chapter 1. Study Design, Regulations, and Ethics in Rabbits for Biomedical Research - p. 1 3. Chapter 2. Future Use of Rabbits in Safety Assessment Regulatory Studies - p. 19 4. Chapter 3. Genetics of Rabbit Models - p. 33 5. Infectious Diseases of Young Rabbits - p. 43 6. Chapter 5. Clinical Examination and Routes of Administration - p. 103 7. Chapter 6. The Alimentary Tract and Exocrine Pancreas - p. 129 8. Chapter 7. The Hepatobiliary System - p. 151 9. Chapter 8. The Urinary System - p. 169 10. Chapter 9. The Nervous System - p. 181 11. Chapter 10. The Eye, Ear, and Ocular Adnexa - p. 205 12. Abstract - p. 205 13. 10.1 Introduction - p. 205 14. 10.2 The eye - p. 205 15. 10.3 Congenital lesions - p. 225 16. 10.4 Degenerative lesions - p. 227 17. 10.5 Inflammatory and vascular lesions - p. 240 18. 10.6 Hyperplastic lesions - p. 247 19. 10.7 Neoplastic lesions - p. 248 20. 10.8 Toxicologic lesions - p. 250 21. 10.9 Miscellaneous lesions and artifacts - p. 250 22. 10.10 The ear - p. 252 23. 10.11 Embryology, anatomy, and physiology - p. 253 24. 10.12 Congenital lesions - p. 261 25. 10.13 Degenerative lesions - p. 261 26. 10.14 Inflammatory and vascular lesions - p. 263 27. 10.15 Hyperplastic and neoplastic lesions - p. 263 28. 10.16 Toxicologic lesions - p. 264 29. 10.17 Artifacts and fixation - p. 264 30. Acknowledgment - p. 264 31. References - p. 264 32. Chapter 11. The Skeletal System and Teeth - p. 283 33. Chapter 12. The Integumentary System - p. 291 34. Chapter 13. The Soft Tissue and Skeletal Muscle - p. 313 35. Chapter 14. The Mammary Gland - p. 323 36. Chapter 15. The Respiratory Tract - p. 329 37. Chapter 16. The Haematopoietic and Lymphoid Systems - p. 349 38. Chapter 17. The Female Reproductive Tract - p. 363 39. Chapter 18. The Male Reproductive Tract - p. 385 40. Chapter 19. The Cardiovascular System - p. 413 41. Chapter 20. The Endocrine System - p. 431 42. Chapter 21. Clinical Pathology - p. 449 43. Index - p. 483
