Gain the in-depth understanding of pathophysiology you need to guide your patient care! Using a systems approach, Pathophysiology, 8th Edition, examines the etiology, pathogenesis, clinical manifestations, and treatment of diseases and disorders. The book begins with a review of normal anatomy and physiology, followed by pathophysiology and application of concepts to specific disorders. Each chapter includes a discussion of the disease processes and abnormalities that may occur, with a focus on the pathophysiologic concepts involved. Written by a team of expert contributors led by Jacquelyn Banasik, this text emphasizes the major pathophysiology concepts relevant to clinical practice while not overwhelming the reader with minute detail.
New to this edition
Key Features
1. 1. Introduction to pathophysiology - p. 1 2. 2. Homeostasis, allostasis, and adaptive responses to stressors - p. 13 3. UNIT II. Cellular Function - p. 28 4. 3. Cell structure and function - p. 29 5. 4. Cell injury, aging, and death - p. 64 6. 5. Genome structure, regulation, and tissue differentiation - p. 83 7. 6. Genetic and developmental disorders - p. 100 8. 7. Neoplasia - p. 122 9. UNIT III. Defense - p. 150 10. 8. Infectious processes - p. 151 11. 9. Inflammation and immunity - p. 167 12. 10. Alterations in immune function - p. 205 13. 11. Malignant disorders of white blood cells - p. 226 14. 12. HIV disease and AIDS - p. 245 15. UNIT IV. Oxygen Transport, Blood Coagulation, Blood Flow, and Blood Pressure - p. 274 16. 13. Alterations in oxygen transport - p. 275 17. 14. Alterations in hemostasis and blood coagulation - p. 307 18. 15. Alterations in blood flow - p. 322 19. 16. Alterations in blood pressure - p. 344 20. UNIT V. Cardiac Function - p. 362 21. 17. Cardiac function - p. 363 22. 18. Alterations in cardiac function - p. 392 23. 19. Heart failure and dysrhythmias: Common Sequelae of Cardiac Diseases - p. 423 24. 20. Shock - p. 446 25. UNIT VI. Respiratory Function - p. 464 26. 21. Respiratory function and alterations in gas exchange - p. 465 27. 22. Obstructive pulmonary disorders - p. 491 28. 23. Restric tive pulmonary disorders - p. 512 29. UNIT VII. Fluid, Electrolyte, and Acid-Base Homeostasis - p. 536 30. 24. Fluid and electrolyte homeostasis and imbalances - p. 537 31. 25. Acid-base homeostasis and imbalances - p. 558 32. UNIT VIII. Renal and Bladder Function - p. 568 33. 26. Renal function - p. 569 34. 27. Intrarenal disorders - p. 592 35. 28. Acute kidney injury and chronic kidney disease - p. 611 36. 29. Disorders of the lower urinary tract - p. 629 37. UNIT IX. Genital and Reproductive Function - p. 648 38. 30. Male genital and reproductive function - p. 649 39. 31. Alterations in male genital and reproductive function - p. 665 40. 32. Female genital and reproductive function - p. 682 41. 33. Alterations in female genital and reproductive function - p. 696 42. 34. Sexually transmitted infections - p. 713 43. UNIT X. Gastrointestinal Function - p. 722 44. 35. Gastrointestinal function - p. 723 45. 36. Gastrointestinal disorders - p. 746 46. 37. Alterations in function of the gallbladder and exocrine pancreas - p. 770 47. 38. Liver diseases - p. 781 48. UNIT XI. Endocrine Function, Metabolism, and Nutrition - p. 812 49. 39. Endocrine physiology an d mechanisms of hypothalamic-pituitary regulation - p. 813 50. 40. Disorders of endocrine function - p. 829 51. 41. Diabetes mellitus - p. 845 52. 42. Alterations in metabolism and nutrition - p. 870 53. UNIT XII. Neural Function - p. 882 54. 43. Structure and function of the nervous system - p. 883 55. 44. Acute disorders of brain function - p. 926 56. 45. Chronic disorders of neurologic function - p. 954 57. 46. Alterations in special sensory function - p. 978 58. 47. Pain - p. 997 59. UNIT XIII. Neuropsychological Function - p. 1014 60. 48. Mental health disorders - p. 1015 61. UNIT XIV. Musculoskeletal Support and Movement - p. 1036 62. 49. Structure and function of the musculoskeletal system - p. 1037 63. 50. Alterations in musculoskeletal function: Trauma, infection, and disease - p. 1057 64. 51. Alterations in musculoskeletal function: Rheumatic disorders - p. 1079 65. UNIT XV. Integumentary System - p. 1096 66. 52. Alterations in the integumentary system - p. 1097 67. 53. Burn injuries - p. 1131 68. Index - p. 1154
Gain the in-depth understanding of pathophysiology you need to guide your patient care! Using a systems approach, Pathophysiology, 8th Edition, examines the etiology, pathogenesis, clinical manifestations, and treatment of diseases and disorders. The book begins with a review of normal anatomy and physiology, followed by pathophysiology and application of concepts to specific disorders. Each chapter includes a discussion of the disease processes and abnormalities that may occur, with a focus on the pathophysiologic concepts involved. Written by a team of expert contributors led by Jacquelyn Banasik, this text emphasizes the major pathophysiology concepts relevant to clinical practice while not overwhelming the reader with minute detail.
New to this edition
Key Features
1. 1. Introduction to pathophysiology - p. 1 2. 2. Homeostasis, allostasis, and adaptive responses to stressors - p. 13 3. UNIT II. Cellular Function - p. 28 4. 3. Cell structure and function - p. 29 5. 4. Cell injury, aging, and death - p. 64 6. 5. Genome structure, regulation, and tissue differentiation - p. 83 7. 6. Genetic and developmental disorders - p. 100 8. 7. Neoplasia - p. 122 9. UNIT III. Defense - p. 150 10. 8. Infectious processes - p. 151 11. 9. Inflammation and immunity - p. 167 12. 10. Alterations in immune function - p. 205 13. 11. Malignant disorders of white blood cells - p. 226 14. 12. HIV disease and AIDS - p. 245 15. UNIT IV. Oxygen Transport, Blood Coagulation, Blood Flow, and Blood Pressure - p. 274 16. 13. Alterations in oxygen transport - p. 275 17. 14. Alterations in hemostasis and blood coagulation - p. 307 18. 15. Alterations in blood flow - p. 322 19. 16. Alterations in blood pressure - p. 344 20. UNIT V. Cardiac Function - p. 362 21. 17. Cardiac function - p. 363 22. 18. Alterations in cardiac function - p. 392 23. 19. Heart failure and dysrhythmias: Common Sequelae of Cardiac Diseases - p. 423 24. 20. Shock - p. 446 25. UNIT VI. Respiratory Function - p. 464 26. 21. Respiratory function and alterations in gas exchange - p. 465 27. 22. Obstructive pulmonary disorders - p. 491 28. 23. Restric tive pulmonary disorders - p. 512 29. UNIT VII. Fluid, Electrolyte, and Acid-Base Homeostasis - p. 536 30. 24. Fluid and electrolyte homeostasis and imbalances - p. 537 31. 25. Acid-base homeostasis and imbalances - p. 558 32. UNIT VIII. Renal and Bladder Function - p. 568 33. 26. Renal function - p. 569 34. 27. Intrarenal disorders - p. 592 35. 28. Acute kidney injury and chronic kidney disease - p. 611 36. 29. Disorders of the lower urinary tract - p. 629 37. UNIT IX. Genital and Reproductive Function - p. 648 38. 30. Male genital and reproductive function - p. 649 39. 31. Alterations in male genital and reproductive function - p. 665 40. 32. Female genital and reproductive function - p. 682 41. 33. Alterations in female genital and reproductive function - p. 696 42. 34. Sexually transmitted infections - p. 713 43. UNIT X. Gastrointestinal Function - p. 722 44. 35. Gastrointestinal function - p. 723 45. 36. Gastrointestinal disorders - p. 746 46. 37. Alterations in function of the gallbladder and exocrine pancreas - p. 770 47. 38. Liver diseases - p. 781 48. UNIT XI. Endocrine Function, Metabolism, and Nutrition - p. 812 49. 39. Endocrine physiology an d mechanisms of hypothalamic-pituitary regulation - p. 813 50. 40. Disorders of endocrine function - p. 829 51. 41. Diabetes mellitus - p. 845 52. 42. Alterations in metabolism and nutrition - p. 870 53. UNIT XII. Neural Function - p. 882 54. 43. Structure and function of the nervous system - p. 883 55. 44. Acute disorders of brain function - p. 926 56. 45. Chronic disorders of neurologic function - p. 954 57. 46. Alterations in special sensory function - p. 978 58. 47. Pain - p. 997 59. UNIT XIII. Neuropsychological Function - p. 1014 60. 48. Mental health disorders - p. 1015 61. UNIT XIV. Musculoskeletal Support and Movement - p. 1036 62. 49. Structure and function of the musculoskeletal system - p. 1037 63. 50. Alterations in musculoskeletal function: Trauma, infection, and disease - p. 1057 64. 51. Alterations in musculoskeletal function: Rheumatic disorders - p. 1079 65. UNIT XV. Integumentary System - p. 1096 66. 52. Alterations in the integumentary system - p. 1097 67. 53. Burn injuries - p. 1131 68. Index - p. 1154
