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Gain the in-depth understanding of pathophysiology you need to guide your patient care! Using a systems approach, Pathophysiology, 8th Edition, examines the etiology, pathogenesis, clinical manifestations, and treatment of diseases and disorders. The book begins with a review of normal anatomy and physiology, followed by pathophysiology and application of concepts to specific disorders. Each chapter includes a discussion of the disease processes and abnormalities that may occur, with a focus on the pathophysiologic concepts involved. Written by a team of expert contributors led by Jacquelyn Banasik, this text emphasizes the major pathophysiology concepts relevant to clinical practice while not overwhelming the reader with minute detail.

  • Clear, easy-to-read writing style emphasizes critical thinking, and includes many tables, boxes, and figures to highlight key content.
  • Thorough updates include information on the newest scientific findings and advances in treatment, more than 100 new figures for improved clarity, and more.
  • More than 1,000 full-color photos and illustrations help to clarify complex pathophysiological concepts.
  • Global Health Care boxes summarize topics such as COVID-19, HIV/AIDS, Ebola, tropical diseases, and more, with information on prevalence, mechanism of disease and transmission.
  • Pediatric and Older Adult Considerations boxes address age-related changes associated with specific body systems.
  • Useful learning resources include chapter outlines, bolded key terms, key questions, Key Points boxes, Clinical Judgment challenges, and chapter summaries.
  • NEW! Updated content throughout the book reflects the latest research and thinking in pathophysiology.

1. 1.  Introduction to pathophysiology - p. 1 2. 2.  Homeostasis, allostasis, and adaptive responses to stressors - p. 13 3. UNIT II. Cellular Function - p. 28 4. 3.  Cell structure and function - p. 29 5. 4.  Cell injury, aging, and death - p. 64 6. 5.  Genome structure, regulation, and tissue differentiation - p. 83 7. 6.  Genetic and developmental disorders - p. 100 8. 7.  Neoplasia - p. 123 9. UNIT III. Defense - p. 150 10. 8.  Infectious processes - p. 151 11. 9.  Inflammation and immunity - p. 167 12. 10.  Alterations in immune function - p. 205 13. 11.  Malignant disorders of white blood cells - p. 227 14. 12.  HIV disease and AIDS - p. 246 15. UNIT IV. Oxygen Transport, Blood Coagulation, Blood Flow, and Blood Pressure - p. 274 16. 13.  Alterations in oxygen transport - p. 275 17. 14.  Alterations in hemostasis and blood coagulation - p. 307 18. 15.  Alterations in blood flow - p. 322 19. 16.  Alterations in blood pressure - p. 345 20. UNIT V. Cardiac Function - p. 362 21. 17.  Cardiac function - p. 363 22. 18.  Alterations in cardiac function - p. 392 23. 19. Heart failure and dysrhythmias: Common Sequelae of Cardiac Diseases - p. 423 24. 20.  Shock - p. 447 25. UNIT VI. Respiratory Function - p. 464 26. 21.  Respiratory function and alterations in gas exchange - p. 465 27. 22.  Obstructive pulmonary disorders - p. 491 28. 23.  Restric tive pulmonary disorders - p. 512 29. UNIT VII. Fluid, Electrolyte, and Acid-Base Homeostasis - p. 536 30. 24.  Fluid and electrolyte homeostasis and imbalances - p. 537 31. 25.  Acid-base homeostasis and imbalances - p. 558 32. UNIT VIII. Renal and Bladder Function - p. 568 33. 26.  Renal function - p. 569 34. 27.  Intrarenal disorders - p. 593 35. 28.  Acute kidney injury and chronic kidney disease - p. 612 36. 29.  Disorders of the lower urinary tract - p. 629 37. UNIT IX. Genital and Reproductive Function - p. 648 38. 30.  Male genital and reproductive function - p. 649 39. 31.  Alterations in male genital and reproductive function - p. 665 40. 32.  Female genital and reproductive function - p. 682 41. 33.  Alterations in female genital and reproductive function - p. 696 42. 34.  Sexually transmitted infections - p. 714 43. UNIT X. Gastrointestinal Function - p. 722 44. 35.  Gastrointestinal function - p. 723 45. 36.  Gastrointestinal disorders - p. 746 46. 37.  Alterations in function of the gallbladder and exocrine pancreas - p. 770 47. 38.  Liver diseases - p. 782 48. UNIT XI. Endocrine Function, Metabolism, and Nutrition - p. 812 49. 39.  Endocrine physiology an d mechanisms of hypothalamic-pituitary regulation - p. 813 50. 40.  Disorders of endocrine function - p. 829 51. 41.  Diabetes mellitus - p. 846 52. 42.  Alterations in metabolism and nutrition - p. 870 53. UNIT XII. Neural Function - p. 882 54. 43.  Structure and function of the nervous system - p. 883 55. 44.  Acute disorders of brain function - p. 926 56. 45.  Chronic disorders of neurologic function - p. 954 57. 46.  Alterations in special sensory function - p. 978 58. 47.  Pain - p. 998 59. UNIT XIII. Neuropsychological Function - p. 1014 60. 48.  Mental health disorders - p. 1015 61. UNIT XIV. Musculoskeletal Support and Movement - p. 1036 62. 49.  Structure and function of the musculoskeletal system - p. 1037 63. 50.  Alterations in musculoskeletal function: Trauma, infection, and disease - p. 1057 64. 51.  Alterations in musculoskeletal function: Rheumatic disorders - p. 1079 65. UNIT XV. Integumentary System - p. 1096 66. 52.  Alterations in the integumentary system - p. 1097 67. 53.  Burn injuries - p. 1132 68. Index - p. 1154

Descripcion
Descripción

Gain the in-depth understanding of pathophysiology you need to guide your patient care! Using a systems approach, Pathophysiology, 8th Edition, examines the etiology, pathogenesis, clinical manifestations, and treatment of diseases and disorders. The book begins with a review of normal anatomy and physiology, followed by pathophysiology and application of concepts to specific disorders. Each chapter includes a discussion of the disease processes and abnormalities that may occur, with a focus on the pathophysiologic concepts involved. Written by a team of expert contributors led by Jacquelyn Banasik, this text emphasizes the major pathophysiology concepts relevant to clinical practice while not overwhelming the reader with minute detail.

  • Clear, easy-to-read writing style emphasizes critical thinking, and includes many tables, boxes, and figures to highlight key content.
  • Thorough updates include information on the newest scientific findings and advances in treatment, more than 100 new figures for improved clarity, and more.
  • More than 1,000 full-color photos and illustrations help to clarify complex pathophysiological concepts.
  • Global Health Care boxes summarize topics such as COVID-19, HIV/AIDS, Ebola, tropical diseases, and more, with information on prevalence, mechanism of disease and transmission.
  • Pediatric and Older Adult Considerations boxes address age-related changes associated with specific body systems.
  • Useful learning resources include chapter outlines, bolded key terms, key questions, Key Points boxes, Clinical Judgment challenges, and chapter summaries.
  • NEW! Updated content throughout the book reflects the latest research and thinking in pathophysiology.

1. 1.  Introduction to pathophysiology - p. 1 2. 2.  Homeostasis, allostasis, and adaptive responses to stressors - p. 13 3. UNIT II. Cellular Function - p. 28 4. 3.  Cell structure and function - p. 29 5. 4.  Cell injury, aging, and death - p. 64 6. 5.  Genome structure, regulation, and tissue differentiation - p. 83 7. 6.  Genetic and developmental disorders - p. 100 8. 7.  Neoplasia - p. 123 9. UNIT III. Defense - p. 150 10. 8.  Infectious processes - p. 151 11. 9.  Inflammation and immunity - p. 167 12. 10.  Alterations in immune function - p. 205 13. 11.  Malignant disorders of white blood cells - p. 227 14. 12.  HIV disease and AIDS - p. 246 15. UNIT IV. Oxygen Transport, Blood Coagulation, Blood Flow, and Blood Pressure - p. 274 16. 13.  Alterations in oxygen transport - p. 275 17. 14.  Alterations in hemostasis and blood coagulation - p. 307 18. 15.  Alterations in blood flow - p. 322 19. 16.  Alterations in blood pressure - p. 345 20. UNIT V. Cardiac Function - p. 362 21. 17.  Cardiac function - p. 363 22. 18.  Alterations in cardiac function - p. 392 23. 19. Heart failure and dysrhythmias: Common Sequelae of Cardiac Diseases - p. 423 24. 20.  Shock - p. 447 25. UNIT VI. Respiratory Function - p. 464 26. 21.  Respiratory function and alterations in gas exchange - p. 465 27. 22.  Obstructive pulmonary disorders - p. 491 28. 23.  Restric tive pulmonary disorders - p. 512 29. UNIT VII. Fluid, Electrolyte, and Acid-Base Homeostasis - p. 536 30. 24.  Fluid and electrolyte homeostasis and imbalances - p. 537 31. 25.  Acid-base homeostasis and imbalances - p. 558 32. UNIT VIII. Renal and Bladder Function - p. 568 33. 26.  Renal function - p. 569 34. 27.  Intrarenal disorders - p. 593 35. 28.  Acute kidney injury and chronic kidney disease - p. 612 36. 29.  Disorders of the lower urinary tract - p. 629 37. UNIT IX. Genital and Reproductive Function - p. 648 38. 30.  Male genital and reproductive function - p. 649 39. 31.  Alterations in male genital and reproductive function - p. 665 40. 32.  Female genital and reproductive function - p. 682 41. 33.  Alterations in female genital and reproductive function - p. 696 42. 34.  Sexually transmitted infections - p. 714 43. UNIT X. Gastrointestinal Function - p. 722 44. 35.  Gastrointestinal function - p. 723 45. 36.  Gastrointestinal disorders - p. 746 46. 37.  Alterations in function of the gallbladder and exocrine pancreas - p. 770 47. 38.  Liver diseases - p. 782 48. UNIT XI. Endocrine Function, Metabolism, and Nutrition - p. 812 49. 39.  Endocrine physiology an d mechanisms of hypothalamic-pituitary regulation - p. 813 50. 40.  Disorders of endocrine function - p. 829 51. 41.  Diabetes mellitus - p. 846 52. 42.  Alterations in metabolism and nutrition - p. 870 53. UNIT XII. Neural Function - p. 882 54. 43.  Structure and function of the nervous system - p. 883 55. 44.  Acute disorders of brain function - p. 926 56. 45.  Chronic disorders of neurologic function - p. 954 57. 46.  Alterations in special sensory function - p. 978 58. 47.  Pain - p. 998 59. UNIT XIII. Neuropsychological Function - p. 1014 60. 48.  Mental health disorders - p. 1015 61. UNIT XIV. Musculoskeletal Support and Movement - p. 1036 62. 49.  Structure and function of the musculoskeletal system - p. 1037 63. 50.  Alterations in musculoskeletal function: Trauma, infection, and disease - p. 1057 64. 51.  Alterations in musculoskeletal function: Rheumatic disorders - p. 1079 65. UNIT XV. Integumentary System - p. 1096 66. 52.  Alterations in the integumentary system - p. 1097 67. 53.  Burn injuries - p. 1132 68. Index - p. 1154

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