Pathophysiology and Treatment of Atherosclerotic Disease in Peripheral Arteries is a thorough review of the disease written by experts studying its detection and treatment. These state-of-the-art chapters summarize in a comprehensive manner emerging knowledge about this important area of medicine. The pathophysiology and treatment of peripheral artery (PAD) disease remains poorly understood even by practitioners. Often it is assumed that PAD should be treated in a similar fashion to coronary artery disease (CAD) when in fact recent data suggest a distinct pathophysiology with genetic risk having some but not complete overlap with CAD. This is a novel reference of emerging data on the factors behind its development and progression, detection, and treatment suggest an emerging paradigm for this disease.
1. 1. Introduction - p. xii 2. 2. Epidemiology of peripheral artery disease - p. 3 3. 3. Atherosclerosis—Pathology of lower extremity atherosclerosis - p. 27 4. 4. Pathology of below-the-knee occlusions and chronic limb ischemia - p. 51 5. 5. Calcium and atherosclerosis in lower extremities - p. 65 6. 6. Current molecular understanding of peripheral arterial disease - p. 81 7. 7. Clinical presentation and diagnosis of PAD - p. 109 8. 8. Medical therapy of PAD - p. 123 9. 9. Intravascular ultrasound: Role in PAD - p. 157 10. 10. Atherectomy in endovascular procedures - p. 175 11. 11. Interventional treatment of PAD: Drug-coated balloons and stents - p. 197 12. 12. Surgical treatment of PAD: Open and endovascular repair - p. 213 13. 13. PAD: Future directions - p. 233 14. Index - p. 235
Pathophysiology and Treatment of Atherosclerotic Disease in Peripheral Arteries is a thorough review of the disease written by experts studying its detection and treatment. These state-of-the-art chapters summarize in a comprehensive manner emerging knowledge about this important area of medicine. The pathophysiology and treatment of peripheral artery (PAD) disease remains poorly understood even by practitioners. Often it is assumed that PAD should be treated in a similar fashion to coronary artery disease (CAD) when in fact recent data suggest a distinct pathophysiology with genetic risk having some but not complete overlap with CAD. This is a novel reference of emerging data on the factors behind its development and progression, detection, and treatment suggest an emerging paradigm for this disease.
1. 1. Introduction - p. xii 2. 2. Epidemiology of peripheral artery disease - p. 3 3. 3. Atherosclerosis—Pathology of lower extremity atherosclerosis - p. 27 4. 4. Pathology of below-the-knee occlusions and chronic limb ischemia - p. 51 5. 5. Calcium and atherosclerosis in lower extremities - p. 65 6. 6. Current molecular understanding of peripheral arterial disease - p. 81 7. 7. Clinical presentation and diagnosis of PAD - p. 109 8. 8. Medical therapy of PAD - p. 123 9. 9. Intravascular ultrasound: Role in PAD - p. 157 10. 10. Atherectomy in endovascular procedures - p. 175 11. 11. Interventional treatment of PAD: Drug-coated balloons and stents - p. 197 12. 12. Surgical treatment of PAD: Open and endovascular repair - p. 213 13. 13. PAD: Future directions - p. 233 14. Index - p. 235
