For more than 30 years, the highly regarded Secrets Series® has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Pediatric Hematology & Oncology Secrets, 2nd Edition, offers practical, up-to-date coverage of the full range of essential topics in this dynamic field. This highly regarded resource features the Secrets’ popular question-and-answer format that also includes lists, tables, pearls, memory aids, and an easy-to-read style – making inquiry, reference, and review quick, easy, and enjoyable.
The proven Secrets Series® format gives you the most return for your time – succinct, easy to read, engaging, and highly effective.
Fully revised and updated, including discussions of supportive care of children with cancer and psychosocial aspects of care.
New chapters on Precision Medicine and Systems Biology; Health Equity and Disparities in Pediatric and Adolescent/Young Adult Oncology; Transfusion Medicine; Neoplastic Hematopathology; Hemophagocytic Lymphohistiocytosis; and more.
Top 100 Secrets and Key Points boxes provide a fast overview of the secrets you must know for success in practice and on exams.
Bulleted lists, mnemonics, practical tips from global leaders in the field – all providing a concise overview of important board-relevant content.
Portable size makes it easy to carry with you for quick reference or review anywhere, anytime.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. iv 5. Contributors - p. v 6. Preface - p. x 7. Dedication - p. xi 8. Top 100 secrets - p. xv 9. I: Hematology - p. xxi 10. Chapter 1: Coagulation overview - p. 2 11. Chapter 2: Developmental erythropoiesis - p. 16 12. Chapter 3: Sickle cell syndromes - p. 19 13. Chapter 4: Intrinsic and extrinsic red blood cell defects - p. 23 14. Chapter 5: Thalassemias - p. 28 15. Chapter 6: Nutritional anemia - p. 32 16. Chapter 7: Granulocytes - p. 39 17. Chapter 8: Disorders of platelets - p. 44 18. Chapter 9: Bone marrow failure syndromes - p. 50 19. Chapter 10: Hematological manifestations of systemic disease - p. 54 20. II: Oncology - p. 56 21. Chapter 11: Epidemiology - p. 58 22. Chapter 12: Principles of chemotherapy - p. 63 23. Chapter 13: Principles of immunotherapy - p. 71 24. Chapter 14: Precision medicine and systems biology - p. 74 25. Chapter 15: Predisposition syndromes - p. 83 26. Chapter 16: Health equity and disparities in pediatric and adolescent/young adult oncology - p. 87 27. Chapter 17: Clinical emergencies in children with cancer - p. 90 28. Chapter 18: Transfusion medicine - p. 93 29. Chapter 19: Pediatric radiation oncology - p. 99 30. Chapter 20: Principles of infectious disease and management of febrile neutropenia - p. 102 31. Chapter 21: Neoplastic hematopathology - p. 105 32. Chapter 22: Pediatric solid tumors pathology - p. 109 33. Chapter 23: Molecular pathology - p. 115 34. Chapter 24: Survivorship and late effects - p. 124 35. Chapter 25: Integrative therapies - p. 132 36. Chapter 26: Palliative Care - p. 136 37. Chapter 27: An overview of the Emotional and educational needs of children with hematological and oncological conditions - p. 145 38. Chapter 28: Global health issues in pediatric oncology - p. 148 39. Chapter 29: Principles of pediatric surgical oncology - p. 154 40. III: Oncologic Diseases - p. 156 41. Chapter 30: Acute lymphoblastic leukemia - p. 158 42. Chapter 31: Acute myeloid leukemia - p. 163 43. Chapter 32: Chronic myeloid leukemia/other leukemia - p. 169 44. Chapter 33: Soft tissue sarcomas - p. 172 45. Chapter 34: Bone tumors - p. 180 46. Chapter 35: Neuroblastoma - p. 187 47. Chapter 36: Hepatic tumors - p. 192 48. Chapter 37: Kidney tumors in children and adolescents - p. 194 49. Chapter 38: Hodgkin lymphoma in children and adolescents - p. 198 50. Chapter 39: Non-hodgkin lymphoma in children and adolescents - p. 202 51. Chapter 40: Neuro-Oncology - p. 212 52. Chapter 41: Post-Transplant lymphoproliferative disorder (PTLD) - p. 219 53. Chapter 42: Retinoblastoma - p. 222 54. Chapter 43: Langerhans Cell Histiocytosis (LCH) - p. 224 55. Chapter 44: Hemophagocytic lymphohistiocytosis - p. 227 56. IV: Stem Cell and Cellular Therapies - p. 233 57. Chapter 45: Principles and practice of pediatric hematopoietic cell transplantation - p. 236 58. Chapter 46: Autologous hematopoietic stem cell transplantation for children and young adults - p. 241 59. Chapter 47: Car-T cells: expanding the universe of immunotherapy in children with malignant diseases - p. 244 60. Chapter 48: Gene therapy for hemoglobinopathies and other diseases - p. 248 61. Chapter 49: Hematopoietic cell transplantation for malignant disorders - p. 252 62. Chapter 50: Stem cell transplantation for children with nonmalignant disorders - p. 254 63. Chapter 51: Complications associated with allogeneic hematopoietic cell transplantation in children - p. 259 64. Index - p. 266
For more than 30 years, the highly regarded Secrets Series® has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Pediatric Hematology & Oncology Secrets, 2nd Edition, offers practical, up-to-date coverage of the full range of essential topics in this dynamic field. This highly regarded resource features the Secrets’ popular question-and-answer format that also includes lists, tables, pearls, memory aids, and an easy-to-read style – making inquiry, reference, and review quick, easy, and enjoyable.
The proven Secrets Series® format gives you the most return for your time – succinct, easy to read, engaging, and highly effective.
Fully revised and updated, including discussions of supportive care of children with cancer and psychosocial aspects of care.
New chapters on Precision Medicine and Systems Biology; Health Equity and Disparities in Pediatric and Adolescent/Young Adult Oncology; Transfusion Medicine; Neoplastic Hematopathology; Hemophagocytic Lymphohistiocytosis; and more.
Top 100 Secrets and Key Points boxes provide a fast overview of the secrets you must know for success in practice and on exams.
Bulleted lists, mnemonics, practical tips from global leaders in the field – all providing a concise overview of important board-relevant content.
Portable size makes it easy to carry with you for quick reference or review anywhere, anytime.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. iv 5. Contributors - p. v 6. Preface - p. x 7. Dedication - p. xi 8. Top 100 secrets - p. xv 9. I: Hematology - p. xxi 10. Chapter 1: Coagulation overview - p. 2 11. Chapter 2: Developmental erythropoiesis - p. 16 12. Chapter 3: Sickle cell syndromes - p. 19 13. Chapter 4: Intrinsic and extrinsic red blood cell defects - p. 23 14. Chapter 5: Thalassemias - p. 28 15. Chapter 6: Nutritional anemia - p. 32 16. Chapter 7: Granulocytes - p. 39 17. Chapter 8: Disorders of platelets - p. 44 18. Chapter 9: Bone marrow failure syndromes - p. 50 19. Chapter 10: Hematological manifestations of systemic disease - p. 54 20. II: Oncology - p. 56 21. Chapter 11: Epidemiology - p. 58 22. Chapter 12: Principles of chemotherapy - p. 63 23. Chapter 13: Principles of immunotherapy - p. 71 24. Chapter 14: Precision medicine and systems biology - p. 74 25. Chapter 15: Predisposition syndromes - p. 83 26. Chapter 16: Health equity and disparities in pediatric and adolescent/young adult oncology - p. 87 27. Chapter 17: Clinical emergencies in children with cancer - p. 90 28. Chapter 18: Transfusion medicine - p. 93 29. Chapter 19: Pediatric radiation oncology - p. 99 30. Chapter 20: Principles of infectious disease and management of febrile neutropenia - p. 102 31. Chapter 21: Neoplastic hematopathology - p. 105 32. Chapter 22: Pediatric solid tumors pathology - p. 109 33. Chapter 23: Molecular pathology - p. 115 34. Chapter 24: Survivorship and late effects - p. 124 35. Chapter 25: Integrative therapies - p. 132 36. Chapter 26: Palliative Care - p. 136 37. Chapter 27: An overview of the Emotional and educational needs of children with hematological and oncological conditions - p. 145 38. Chapter 28: Global health issues in pediatric oncology - p. 148 39. Chapter 29: Principles of pediatric surgical oncology - p. 154 40. III: Oncologic Diseases - p. 156 41. Chapter 30: Acute lymphoblastic leukemia - p. 158 42. Chapter 31: Acute myeloid leukemia - p. 163 43. Chapter 32: Chronic myeloid leukemia/other leukemia - p. 169 44. Chapter 33: Soft tissue sarcomas - p. 172 45. Chapter 34: Bone tumors - p. 180 46. Chapter 35: Neuroblastoma - p. 187 47. Chapter 36: Hepatic tumors - p. 192 48. Chapter 37: Kidney tumors in children and adolescents - p. 194 49. Chapter 38: Hodgkin lymphoma in children and adolescents - p. 198 50. Chapter 39: Non-hodgkin lymphoma in children and adolescents - p. 202 51. Chapter 40: Neuro-Oncology - p. 212 52. Chapter 41: Post-Transplant lymphoproliferative disorder (PTLD) - p. 219 53. Chapter 42: Retinoblastoma - p. 222 54. Chapter 43: Langerhans Cell Histiocytosis (LCH) - p. 224 55. Chapter 44: Hemophagocytic lymphohistiocytosis - p. 227 56. IV: Stem Cell and Cellular Therapies - p. 233 57. Chapter 45: Principles and practice of pediatric hematopoietic cell transplantation - p. 236 58. Chapter 46: Autologous hematopoietic stem cell transplantation for children and young adults - p. 241 59. Chapter 47: Car-T cells: expanding the universe of immunotherapy in children with malignant diseases - p. 244 60. Chapter 48: Gene therapy for hemoglobinopathies and other diseases - p. 248 61. Chapter 49: Hematopoietic cell transplantation for malignant disorders - p. 252 62. Chapter 50: Stem cell transplantation for children with nonmalignant disorders - p. 254 63. Chapter 51: Complications associated with allogeneic hematopoietic cell transplantation in children - p. 259 64. Index - p. 266
