For more than 30 years, the highly regarded Secrets Series® has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Pediatric Hematology & Oncology Secrets, 2nd Edition, offers practical, up-to-date coverage of the full range of essential topics in this dynamic field. This highly regarded resource features the Secrets’ popular question-and-answer format that also includes lists, tables, pearls, memory aids, and an easy-to-read style – making inquiry, reference, and review quick, easy, and enjoyable.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. ii 4. Copyright - p. iv 5. Contributors - p. v 6. Preface - p. x 7. Dedication - p. xi 8. Top 100 secrets - p. xv 9. I: Hematology - p. 1 10. Chapter 1: Coagulation overview - p. 2 11. Chapter 2: Developmental erythropoiesis - p. 16 12. Chapter 3: Sickle cell syndromes - p. 19 13. Chapter 4: Intrinsic and extrinsic red blood cell defects - p. 23 14. Chapter 5: Thalassemias - p. 28 15. Chapter 6: Nutritional anemia - p. 32 16. Chapter 7: Granulocytes - p. 39 17. Chapter 8: Disorders of platelets - p. 44 18. Chapter 9: Bone marrow failure syndromes - p. 50 19. Chapter 10: Hematological manifestations of systemic disease - p. 54 20. II: Oncology - p. 57 21. Chapter 11: Epidemiology - p. 58 22. Chapter 12: Principles of chemotherapy - p. 63 23. Chapter 13: Principles of immunotherapy - p. 71 24. Chapter 14: Precision medicine and systems biology - p. 74 25. Chapter 15: Predisposition syndromes - p. 83 26. Chapter 16: Health equity and disparities in pediatric and adolescent/young adult oncology - p. 87 27. Chapter 17: Clinical emergencies in children with cancer - p. 90 28. Chapter 18: Transfusion medicine - p. 93 29. Chapter 19: Pediatric radiation oncology - p. 99 30. Chapter 20: Principles of infectious disease and management of febrile neutropenia - p. 102 31. Chapter 21: Neoplastic hematopathology - p. 105 32. Chapter 22: Pediatric solid tumors pathology - p. 109 33. Chapter 23: Molecular pathology - p. 115 34. Chapter 24: Survivorship and late effects - p. 124 35. Chapter 25: Integrative therapies - p. 132 36. Chapter 26: Palliative Care - p. 136 37. Chapter 27: An overview of the Emotional and educational needs of children with hematological and oncological conditions - p. 145 38. Chapter 28: Global health issues in pediatric oncology - p. 148 39. Chapter 29: Principles of pediatric surgical oncology - p. 154 40. III: Oncologic Diseases - p. 156 41. Chapter 30: Acute lymphoblastic leukemia - p. 158 42. Chapter 31: Acute myeloid leukemia - p. 163 43. Chapter 32: Chronic myeloid leukemia/other leukemia - p. 169 44. Chapter 33: Soft tissue sarcomas - p. 172 45. Chapter 34: Bone tumors - p. 180 46. Chapter 35: Neuroblastoma - p. 187 47. Chapter 36: Hepatic tumors - p. 192 48. Chapter 37: Kidney tumors in children and adolescents - p. 194 49. Chapter 38: Hodgkin lymphoma in children and adolescents - p. 198 50. Chapter 39: Non-hodgkin lymphoma in children and adolescents - p. 202 51. Chapter 40: Neuro-Oncology - p. 212 52. Chapter 41: Post-Transplant lymphoproliferative disorder (PTLD) - p. 219 53. Chapter 42: Retinoblastoma - p. 222 54. Chapter 43: Langerhans Cell Histiocytosis (LCH) - p. 224 55. Chapter 44: Hemophagocytic lymphohistiocytosis - p. 227 56. IV: Stem Cell and Cellular Therapies - p. 234 57. Chapter 45: Principles and practice of pediatric hematopoietic cell transplantation - p. 236 58. Chapter 46: Autologous hematopoietic stem cell transplantation for children and young adults - p. 241 59. Chapter 47: Car-T cells: expanding the universe of immunotherapy in children with malignant diseases - p. 244 60. Chapter 48: Gene therapy for hemoglobinopathies and other diseases - p. 248 61. Chapter 49: Hematopoietic cell transplantation for malignant disorders - p. 252 62. Chapter 50: Stem cell transplantation for children with nonmalignant disorders - p. 254 63. Chapter 51: Complications associated with allogeneic hematopoietic cell transplantation in children - p. 259 64. Index - p. 266
For more than 30 years, the highly regarded Secrets Series® has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Pediatric Hematology & Oncology Secrets, 2nd Edition, offers practical, up-to-date coverage of the full range of essential topics in this dynamic field. This highly regarded resource features the Secrets’ popular question-and-answer format that also includes lists, tables, pearls, memory aids, and an easy-to-read style – making inquiry, reference, and review quick, easy, and enjoyable.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. ii 4. Copyright - p. iv 5. Contributors - p. v 6. Preface - p. x 7. Dedication - p. xi 8. Top 100 secrets - p. xv 9. I: Hematology - p. 1 10. Chapter 1: Coagulation overview - p. 2 11. Chapter 2: Developmental erythropoiesis - p. 16 12. Chapter 3: Sickle cell syndromes - p. 19 13. Chapter 4: Intrinsic and extrinsic red blood cell defects - p. 23 14. Chapter 5: Thalassemias - p. 28 15. Chapter 6: Nutritional anemia - p. 32 16. Chapter 7: Granulocytes - p. 39 17. Chapter 8: Disorders of platelets - p. 44 18. Chapter 9: Bone marrow failure syndromes - p. 50 19. Chapter 10: Hematological manifestations of systemic disease - p. 54 20. II: Oncology - p. 57 21. Chapter 11: Epidemiology - p. 58 22. Chapter 12: Principles of chemotherapy - p. 63 23. Chapter 13: Principles of immunotherapy - p. 71 24. Chapter 14: Precision medicine and systems biology - p. 74 25. Chapter 15: Predisposition syndromes - p. 83 26. Chapter 16: Health equity and disparities in pediatric and adolescent/young adult oncology - p. 87 27. Chapter 17: Clinical emergencies in children with cancer - p. 90 28. Chapter 18: Transfusion medicine - p. 93 29. Chapter 19: Pediatric radiation oncology - p. 99 30. Chapter 20: Principles of infectious disease and management of febrile neutropenia - p. 102 31. Chapter 21: Neoplastic hematopathology - p. 105 32. Chapter 22: Pediatric solid tumors pathology - p. 109 33. Chapter 23: Molecular pathology - p. 115 34. Chapter 24: Survivorship and late effects - p. 124 35. Chapter 25: Integrative therapies - p. 132 36. Chapter 26: Palliative Care - p. 136 37. Chapter 27: An overview of the Emotional and educational needs of children with hematological and oncological conditions - p. 145 38. Chapter 28: Global health issues in pediatric oncology - p. 148 39. Chapter 29: Principles of pediatric surgical oncology - p. 154 40. III: Oncologic Diseases - p. 156 41. Chapter 30: Acute lymphoblastic leukemia - p. 158 42. Chapter 31: Acute myeloid leukemia - p. 163 43. Chapter 32: Chronic myeloid leukemia/other leukemia - p. 169 44. Chapter 33: Soft tissue sarcomas - p. 172 45. Chapter 34: Bone tumors - p. 180 46. Chapter 35: Neuroblastoma - p. 187 47. Chapter 36: Hepatic tumors - p. 192 48. Chapter 37: Kidney tumors in children and adolescents - p. 194 49. Chapter 38: Hodgkin lymphoma in children and adolescents - p. 198 50. Chapter 39: Non-hodgkin lymphoma in children and adolescents - p. 202 51. Chapter 40: Neuro-Oncology - p. 212 52. Chapter 41: Post-Transplant lymphoproliferative disorder (PTLD) - p. 219 53. Chapter 42: Retinoblastoma - p. 222 54. Chapter 43: Langerhans Cell Histiocytosis (LCH) - p. 224 55. Chapter 44: Hemophagocytic lymphohistiocytosis - p. 227 56. IV: Stem Cell and Cellular Therapies - p. 234 57. Chapter 45: Principles and practice of pediatric hematopoietic cell transplantation - p. 236 58. Chapter 46: Autologous hematopoietic stem cell transplantation for children and young adults - p. 241 59. Chapter 47: Car-T cells: expanding the universe of immunotherapy in children with malignant diseases - p. 244 60. Chapter 48: Gene therapy for hemoglobinopathies and other diseases - p. 248 61. Chapter 49: Hematopoietic cell transplantation for malignant disorders - p. 252 62. Chapter 50: Stem cell transplantation for children with nonmalignant disorders - p. 254 63. Chapter 51: Complications associated with allogeneic hematopoietic cell transplantation in children - p. 259 64. Index - p. 266
