Peptide and Protein Drug Delivery Using Polysaccharides offers an interdisciplinary discussion of polysaccharides applied in peptide and protein drug delivery. Chapters consider basic biology of different polysaccharides of current interest and their production at pilot and large-scale stages by various techniques including, but not limited to, cell and hairy root cultures. Other sections examine factors affecting polysaccharide absorption, metabolism, and excretion in nascent, encapsulated, or conjugated forms, with unique coverage of vaccine absorption, metabolism, and drug delivery. A final section considers analytical methods for detection in tissue fluids and homogenates. Accessible figures, tables, and graphical abstracts are included throughout to support understanding.
Specific polysaccharides discussed for therapeutic purposes include cellulose, hyaluronic acid, heparin, carageenan, alginic acid, agar and myrrh, acacia, tragacanth, ghatti gum, chitin, chitosan, starch, glycogen and dextran.
1. Peptide and Protein Drug Delivery Using Polysaccharides - p. Page i 2. Cover - p. Page i 3. Title page - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iii 6. Contents - p. Page vi 7. List of contributors - p. Page vii 8. About the editors - p. Page vii 9. List of Illustrations - p. Page ix 10. List of Tables - p. Page x 11. Chapter 1 : Peptide and protein in therapeutics - p. Page x 12. Chapter 2 : Hairy root culture: a reliable bioreactor from transgenic plants - p. Page 21 13. Chapter 3 : Strategies for the ameliorated production of pharmaceutically important glycosides via plant cell culture - p. Page 42 14. Chapter 4 : Peptide and protein delivery through cellulose, hyaluronic acid, and heparin - p. Page 68 15. Chapter 5 : Peptide and protein delivery through carrageenan, alginic acid, agar, and myrrh - p. Page 103 16. Chapter 6 : Peptide and protein delivery through acacia, tragacanth, and ghatti gum - p. Page 143 17. Chapter 7 : Protein and peptide delivery through chitin, chitosan, and starch - p. Page 162 18. Chapter 8 : Protein and peptide delivery through glycogen and dextran - p. Page 191 19. Chapter 9 : Peptide and protein in vaccine delivery - p. Page 211 20. Chapter 10 : Analytical methods in the detection of proteins and peptides in tissue fluids and homogenates - p. Page 231 21. Chapter 11 : Factors affecting peptide and protein absorption, metabolism, and excretion - p. Page 257 22. Index - p. Page 284
Peptide and Protein Drug Delivery Using Polysaccharides offers an interdisciplinary discussion of polysaccharides applied in peptide and protein drug delivery. Chapters consider basic biology of different polysaccharides of current interest and their production at pilot and large-scale stages by various techniques including, but not limited to, cell and hairy root cultures. Other sections examine factors affecting polysaccharide absorption, metabolism, and excretion in nascent, encapsulated, or conjugated forms, with unique coverage of vaccine absorption, metabolism, and drug delivery. A final section considers analytical methods for detection in tissue fluids and homogenates. Accessible figures, tables, and graphical abstracts are included throughout to support understanding.
Specific polysaccharides discussed for therapeutic purposes include cellulose, hyaluronic acid, heparin, carageenan, alginic acid, agar and myrrh, acacia, tragacanth, ghatti gum, chitin, chitosan, starch, glycogen and dextran.
1. Peptide and Protein Drug Delivery Using Polysaccharides - p. Page i 2. Cover - p. Page i 3. Title page - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iii 6. Contents - p. Page vi 7. List of contributors - p. Page vii 8. About the editors - p. Page vii 9. List of Illustrations - p. Page ix 10. List of Tables - p. Page x 11. Chapter 1 : Peptide and protein in therapeutics - p. Page x 12. Chapter 2 : Hairy root culture: a reliable bioreactor from transgenic plants - p. Page 21 13. Chapter 3 : Strategies for the ameliorated production of pharmaceutically important glycosides via plant cell culture - p. Page 42 14. Chapter 4 : Peptide and protein delivery through cellulose, hyaluronic acid, and heparin - p. Page 68 15. Chapter 5 : Peptide and protein delivery through carrageenan, alginic acid, agar, and myrrh - p. Page 103 16. Chapter 6 : Peptide and protein delivery through acacia, tragacanth, and ghatti gum - p. Page 143 17. Chapter 7 : Protein and peptide delivery through chitin, chitosan, and starch - p. Page 162 18. Chapter 8 : Protein and peptide delivery through glycogen and dextran - p. Page 191 19. Chapter 9 : Peptide and protein in vaccine delivery - p. Page 211 20. Chapter 10 : Analytical methods in the detection of proteins and peptides in tissue fluids and homogenates - p. Page 231 21. Chapter 11 : Factors affecting peptide and protein absorption, metabolism, and excretion - p. Page 257 22. Index - p. Page 284
