The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized, and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evaluation. However, both 5-HT6 antagonists and agonists seem to exert potential antidepressant activity. Recently, a second messenger system has been discovered. 5-HT6 receptor function is becoming more and more intriguing. Thus, the aim of the present book is to try to clarify the pharmacology of 5-HT6 receptors.
1. Cover 2. Contents 3. Pharmacology of 5-HT6 Receptors, Part II 4. Copyright 5. Contributors 6. Preface 7. The Central Role of 5-HT6 Receptors in Modulating Brain Neurochemistry 8. 5-HT6 Receptor Memory and Amnesia: Behavioral Pharmacology – Learning and Memory Processes 9. Behavioral Pharmacology: Potential Antidepressant and Anxiolytic Properties 10. The 5-HT6 Receptor as a Target for Developing Novel Antiobesity Drugs 11. Behavioral and Neurochemical Pharmacology of 5-HT6 Receptors Related to Reward and Reinforcement 12. 5-HT6 Receptor Ligands and their Antipsychotic Potential 13. 5-HT6 Receptor Ligands as Antidementia Drugs 14. Other 5-HT6 Receptor-Mediated Effects 15. Index 16. Contents of Recent Volumes
The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized, and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evaluation. However, both 5-HT6 antagonists and agonists seem to exert potential antidepressant activity. Recently, a second messenger system has been discovered. 5-HT6 receptor function is becoming more and more intriguing. Thus, the aim of the present book is to try to clarify the pharmacology of 5-HT6 receptors.
1. Cover 2. Contents 3. Pharmacology of 5-HT6 Receptors, Part II 4. Copyright 5. Contributors 6. Preface 7. The Central Role of 5-HT6 Receptors in Modulating Brain Neurochemistry 8. 5-HT6 Receptor Memory and Amnesia: Behavioral Pharmacology – Learning and Memory Processes 9. Behavioral Pharmacology: Potential Antidepressant and Anxiolytic Properties 10. The 5-HT6 Receptor as a Target for Developing Novel Antiobesity Drugs 11. Behavioral and Neurochemical Pharmacology of 5-HT6 Receptors Related to Reward and Reinforcement 12. 5-HT6 Receptor Ligands and their Antipsychotic Potential 13. 5-HT6 Receptor Ligands as Antidementia Drugs 14. Other 5-HT6 Receptor-Mediated Effects 15. Index 16. Contents of Recent Volumes
