Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions provides an in-depth examination of the molecular mechanisms of phytochemicals and their potential in treating metabolic diseases. This comprehensive guide begins with an introduction to the prevalence and impact of metabolic disorders, emphasizing the significant role of phytochemicals in their management. The book delves into scientific concepts and research findings, offering valuable insights for researchers and healthcare professionals in the fields of molecular biology, biochemistry, pharmacology, and biotechnology. Chapters cover various crucial topics such as oxidative stress, epigenetic mechanisms, and mitophagy.
In addition, they explore the targeting of molecular chaperones and the molecular targets of plant nutraceuticals for treating obesity, cardiovascular disease, and type 2 diabetes. The book also addresses technological advances, including AI and nanotechnology, highlighting opportunities and challenges in improving the use of plant molecules for metabolic disorder treatments. It serves as an essential resource for those engaged in drug discovery and related areas.
1. Section I Introduction - p. 1 2. Chapter 1 Overview of lifestyle-related metabolic disorders - p. 3 3. Section II Phytochemicals and molecular targets - p. 13 4. Chapter 2 Significance of phytochemicals in metabolic disorders - p. 15 5. Chapter 3 Exploring the role of phytochemicals in managing metabolic disorders - p. 51 6. Chapter 4 Enhancing understanding of phytochemicals’ role in managing metabolic disorders - p. 81 7. Chapter 5 Molecular connection of oxidative stress and metabolic syndrome: Therapeutic role of phytocomponents - p. 131 8. Chapter 6 Epigenetic mechanisms of phytochemicals in the cure of metabolic diseases - p. 153 9. Chapter 7 Epigenetics mechanisms of phytochemicals in cure of metabolic diseases - p. 165 10. Chapter 8 Plant‑derived bioactive peptides for treatment of metabolic disorders - p. 183 11. Chapter 9 Efficiency of phytochemicals to cure metabolic diseases by targeting mitophagy - p. 209 12. Chapter 10 The potential of phytochemicals in mitophagy-driven treatment of metabolic diseases - p. 219 13. Chapter 11 Phytochemicals as promising therapeutic approaches for inflammasomes-related metabolic disorders - p. 235 14. Chapter 12 Regulatory impact of phytochemicals on metabolic diseases by targeting Nrf2-ARE signaling mechanism - p. 259 15. Chapter 13 Targeting molecular chaperones with phytochemicals for drug discovery in metabolic ailment - p. 289 16. Section III Nanotechnology methods - p. 313 17. Chapter 14 Molecular targets of plant nutraceuticals against obesity - p. 315 18. Section IV Clinical study - p. 343 19. Chapter 15 Navigating molecular targets: Plant nutraceuticals in the battle against obesity - p. 345 20. Section V Technologies and challenges for plant-based drug discovery - p. 373 21. Chapter 16 Molecular insight to cure cardiovascular diseases through plant compounds - p. 375 22. Chapter 17 Mechanistic insights of important medicinal plant compounds in managing type 2 diabetes mellitus - p. 405 23. Chapter 18 Attenuation of hyperlipidemia by medicinal plants with nanotechnological methods - p. 439 24. Chapter 19 Nanotechnological aspects in the development of phyto-therapeutics against metabolic disorders - p. 461 25. Chapter 20 Clinical evidence of phytochemicals in the management of metabolic diseases - p. 495 26. Chapter 21 Integration of artificial intelligence with traditional medicine for treating diabetes - p. 515 27. Chapter 22 Integration of high-throughput omics technologies in discovery of phytodrugs to treat metabolic diseases - p. 537 28. Chapter 23 Multitargets drug design for screening of phytochemicals to cure metabolic disorders - p. 561 29. Chapter 24 New opportunities and challenges for improving the drug ability of plant products against metabolic disorders - p. 591 30. Index - p. 605
Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions provides an in-depth examination of the molecular mechanisms of phytochemicals and their potential in treating metabolic diseases. This comprehensive guide begins with an introduction to the prevalence and impact of metabolic disorders, emphasizing the significant role of phytochemicals in their management. The book delves into scientific concepts and research findings, offering valuable insights for researchers and healthcare professionals in the fields of molecular biology, biochemistry, pharmacology, and biotechnology. Chapters cover various crucial topics such as oxidative stress, epigenetic mechanisms, and mitophagy.
In addition, they explore the targeting of molecular chaperones and the molecular targets of plant nutraceuticals for treating obesity, cardiovascular disease, and type 2 diabetes. The book also addresses technological advances, including AI and nanotechnology, highlighting opportunities and challenges in improving the use of plant molecules for metabolic disorder treatments. It serves as an essential resource for those engaged in drug discovery and related areas.
1. Section I Introduction - p. 1 2. Chapter 1 Overview of lifestyle-related metabolic disorders - p. 3 3. Section II Phytochemicals and molecular targets - p. 13 4. Chapter 2 Significance of phytochemicals in metabolic disorders - p. 15 5. Chapter 3 Exploring the role of phytochemicals in managing metabolic disorders - p. 51 6. Chapter 4 Enhancing understanding of phytochemicals’ role in managing metabolic disorders - p. 81 7. Chapter 5 Molecular connection of oxidative stress and metabolic syndrome: Therapeutic role of phytocomponents - p. 131 8. Chapter 6 Epigenetic mechanisms of phytochemicals in the cure of metabolic diseases - p. 153 9. Chapter 7 Epigenetics mechanisms of phytochemicals in cure of metabolic diseases - p. 165 10. Chapter 8 Plant‑derived bioactive peptides for treatment of metabolic disorders - p. 183 11. Chapter 9 Efficiency of phytochemicals to cure metabolic diseases by targeting mitophagy - p. 209 12. Chapter 10 The potential of phytochemicals in mitophagy-driven treatment of metabolic diseases - p. 219 13. Chapter 11 Phytochemicals as promising therapeutic approaches for inflammasomes-related metabolic disorders - p. 235 14. Chapter 12 Regulatory impact of phytochemicals on metabolic diseases by targeting Nrf2-ARE signaling mechanism - p. 259 15. Chapter 13 Targeting molecular chaperones with phytochemicals for drug discovery in metabolic ailment - p. 289 16. Section III Nanotechnology methods - p. 313 17. Chapter 14 Molecular targets of plant nutraceuticals against obesity - p. 315 18. Section IV Clinical study - p. 343 19. Chapter 15 Navigating molecular targets: Plant nutraceuticals in the battle against obesity - p. 345 20. Section V Technologies and challenges for plant-based drug discovery - p. 373 21. Chapter 16 Molecular insight to cure cardiovascular diseases through plant compounds - p. 375 22. Chapter 17 Mechanistic insights of important medicinal plant compounds in managing type 2 diabetes mellitus - p. 405 23. Chapter 18 Attenuation of hyperlipidemia by medicinal plants with nanotechnological methods - p. 439 24. Chapter 19 Nanotechnological aspects in the development of phyto-therapeutics against metabolic disorders - p. 461 25. Chapter 20 Clinical evidence of phytochemicals in the management of metabolic diseases - p. 495 26. Chapter 21 Integration of artificial intelligence with traditional medicine for treating diabetes - p. 515 27. Chapter 22 Integration of high-throughput omics technologies in discovery of phytodrugs to treat metabolic diseases - p. 537 28. Chapter 23 Multitargets drug design for screening of phytochemicals to cure metabolic disorders - p. 561 29. Chapter 24 New opportunities and challenges for improving the drug ability of plant products against metabolic disorders - p. 591 30. Index - p. 605
