Polymers for Oral Drug Delivery Technologies covers the fundamentals of oral drug delivery and various aspects of polymer technology in oral drug delivery, from classification and synthesis, to applications and regulatory factors. It presents the oral delivery?of therapeutics for treating a number of diseases, along with the challenges of oral drug administration to assure a predictive and reproducible pharmacokinetic profile of active pharmaceutical ingredients (API).
Polymers play an important role to achieve the targeted release profile consistently of an API in vivo by various functionalities like drug protection from gastric juice, fast release and supersaturation or release within a targeted area of the GI tract.
1. Polymers for Oral Drug Delivery Technologies - p. Page i 2. Cover - p. Page i 3. Title page - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iii 6. Contents - p. Page vi 7. List of contributors - p. Page vii 8. Preface - p. Page vii 9. List of Illustrations - p. Page ix 10. List of Tables - p. Page x 11. 1 : Gastrointestinal tract environment and its implications on oral drug delivery - p. Page x 12. 2 : Gastrointestinal tract motility and transport - p. Page 43 13. 3 : Drug absorption and presystemic metabolism and pharmacokinetic modeling - p. Page 76 14. 4 : In vitro dissolution and predictive release testing - p. Page 134 15. 5 : Principle characteristics and specification of pharmaceutical polymers - p. Page 187 16. 6 : Regulatory aspects of polymers used and new polymers for oral medication of gastroretentive dosage forms - p. Page 223 17. 7 : Classes/types of polymers used in oral delivery (natural, semisynthetic, synthetic), their chemical structure and general functionalities - p. Page 255 18. 8 : Role of polymers in tableting - p. Page 301 19. 9 : Capsule-forming polymers - p. Page 378 20. 10 : Dry and wet granulation - p. Page 434 21. 11 : Matrix formers - p. Page 491 22. 12 : Functional polymeric coatings for immediate release dosage forms - p. Page 516 23. 13 : Polymeric carriers for amorphous solid dispersion - p. Page 538 24. 14 : Micro/nanoparticles - p. Page 567 25. 15 : Taste masking polymers - p. Page 612 26. 16 : Polymers in orally disintegrating tablets and orally dissolving films - p. Page 654 27. 17 : Additive manufacturing (3d printing) - p. Page 670 28. 18 : Mucoadhesive forms - p. Page 695 29. 19 : Gastroretentive dosage forms - p. Page 740 30. 20 : Polymer blends and additives - p. Page 784 31. Index - p. Page 804
Polymers for Oral Drug Delivery Technologies covers the fundamentals of oral drug delivery and various aspects of polymer technology in oral drug delivery, from classification and synthesis, to applications and regulatory factors. It presents the oral delivery?of therapeutics for treating a number of diseases, along with the challenges of oral drug administration to assure a predictive and reproducible pharmacokinetic profile of active pharmaceutical ingredients (API).
Polymers play an important role to achieve the targeted release profile consistently of an API in vivo by various functionalities like drug protection from gastric juice, fast release and supersaturation or release within a targeted area of the GI tract.
1. Polymers for Oral Drug Delivery Technologies - p. Page i 2. Cover - p. Page i 3. Title page - p. Page ii 4. Table of Contents - p. Page iii 5. Copyright - p. Page iii 6. Contents - p. Page vi 7. List of contributors - p. Page vii 8. Preface - p. Page vii 9. List of Illustrations - p. Page ix 10. List of Tables - p. Page x 11. 1 : Gastrointestinal tract environment and its implications on oral drug delivery - p. Page x 12. 2 : Gastrointestinal tract motility and transport - p. Page 43 13. 3 : Drug absorption and presystemic metabolism and pharmacokinetic modeling - p. Page 76 14. 4 : In vitro dissolution and predictive release testing - p. Page 134 15. 5 : Principle characteristics and specification of pharmaceutical polymers - p. Page 187 16. 6 : Regulatory aspects of polymers used and new polymers for oral medication of gastroretentive dosage forms - p. Page 223 17. 7 : Classes/types of polymers used in oral delivery (natural, semisynthetic, synthetic), their chemical structure and general functionalities - p. Page 255 18. 8 : Role of polymers in tableting - p. Page 301 19. 9 : Capsule-forming polymers - p. Page 378 20. 10 : Dry and wet granulation - p. Page 434 21. 11 : Matrix formers - p. Page 491 22. 12 : Functional polymeric coatings for immediate release dosage forms - p. Page 516 23. 13 : Polymeric carriers for amorphous solid dispersion - p. Page 538 24. 14 : Micro/nanoparticles - p. Page 567 25. 15 : Taste masking polymers - p. Page 612 26. 16 : Polymers in orally disintegrating tablets and orally dissolving films - p. Page 654 27. 17 : Additive manufacturing (3d printing) - p. Page 670 28. 18 : Mucoadhesive forms - p. Page 695 29. 19 : Gastroretentive dosage forms - p. Page 740 30. 20 : Polymer blends and additives - p. Page 784 31. Index - p. Page 804
