Principles and Clinical Diagnostic Applications of Surface-Enhanced Raman Spectroscopy summarizes the principles of surface-enhanced Raman scattering/spectroscopy (SERS) and plasmonic nanomaterials for SERS, with a focus on SERS applications in clinical diagnostics. This book covers the key concepts from the fundamentals, materials, experimental aspects, and applications of SERS in clinical diagnostics with discussions on label-free/direct SERS assay, design and synthesis of SERS nanotags, SERS nanotags for point-of-care diagnostics, microfluidic SERS assay, and in vitro and in vivo sensing and imaging. Written by experts from around the world, this comprehensive volume showcases the recent progress of SERS applications in clinical diagnostics and helps readers understand when and how to use SERS in a clinical setting.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xi 7. Chapter 1. Principles of surface-enhanced Raman spectroscopy - p. 1 8. Chapter 2. Nanoplasmonic materials for surface-enhanced Raman scattering - p. 33 9. Chapter 3. Experimental aspects of surface-enhanced Raman scattering for biological applications - p. 81 10. Chapter 4. Label-free surface-enhanced Raman scattering for clinical applications - p. 125 11. Chapter 5. Surface-enhanced Raman scattering nanotags design and synthesis - p. 171 12. Chapter 6. Surface-enhanced Raman spectroscopy for circulating biomarkers detection in clinical diagnosis - p. 225 13. Chapter 7. Surface-enhanced Raman spectroscopy-based microfluidic devices for in vitro diagnostics - p. 281 14. Chapter 8. SERS for sensing and imaging in live cells - p. 303 15. Chapter 9. iSERS microscopy: point-of-care diagnosis and tissue imaging - p. 327 16. Chapter 10. Surface-enhanced Raman spectroscopy for cancer characterization - p. 373 17. Chapter 11. Multivariate approaches for SERS data analysis in clinical applications - p. 395 18. Index - p. 433
Principles and Clinical Diagnostic Applications of Surface-Enhanced Raman Spectroscopy summarizes the principles of surface-enhanced Raman scattering/spectroscopy (SERS) and plasmonic nanomaterials for SERS, with a focus on SERS applications in clinical diagnostics. This book covers the key concepts from the fundamentals, materials, experimental aspects, and applications of SERS in clinical diagnostics with discussions on label-free/direct SERS assay, design and synthesis of SERS nanotags, SERS nanotags for point-of-care diagnostics, microfluidic SERS assay, and in vitro and in vivo sensing and imaging. Written by experts from around the world, this comprehensive volume showcases the recent progress of SERS applications in clinical diagnostics and helps readers understand when and how to use SERS in a clinical setting.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. List of contributors - p. xi 7. Chapter 1. Principles of surface-enhanced Raman spectroscopy - p. 1 8. Chapter 2. Nanoplasmonic materials for surface-enhanced Raman scattering - p. 33 9. Chapter 3. Experimental aspects of surface-enhanced Raman scattering for biological applications - p. 81 10. Chapter 4. Label-free surface-enhanced Raman scattering for clinical applications - p. 125 11. Chapter 5. Surface-enhanced Raman scattering nanotags design and synthesis - p. 171 12. Chapter 6. Surface-enhanced Raman spectroscopy for circulating biomarkers detection in clinical diagnosis - p. 225 13. Chapter 7. Surface-enhanced Raman spectroscopy-based microfluidic devices for in vitro diagnostics - p. 281 14. Chapter 8. SERS for sensing and imaging in live cells - p. 303 15. Chapter 9. iSERS microscopy: point-of-care diagnosis and tissue imaging - p. 327 16. Chapter 10. Surface-enhanced Raman spectroscopy for cancer characterization - p. 373 17. Chapter 11. Multivariate approaches for SERS data analysis in clinical applications - p. 395 18. Index - p. 433
