Recent Developments in the Synthesis and Applications of Pyridines is a comprehensive handbook for organic chemists working on innovative approaches to the synthesis of pyridines. Written by scientists in both academia and industry and designed to be a standalone reference, the book features reviews, research results and case studies on synthetic methods and applications of pyridine-based chemotypes. The book will bridge the gap between industry and academia by presenting recent innovative approaches to the synthesis of pyridines, diverse application of pyridines in drug development, heterogeneous catalysis and material science, as well as benchtop to shelf narratives of pyridine-based compounds in the industry.
The role of computational chemistry in the development of pyridine-based bioactive molecules is also included. This reference is essential for researchers in organic chemistry both in academic and industrial settings, postgraduates in chemistry and medicinal chemistry.
1. Recent Developments in the Synthesis and Applications of Pyridines - p. iii 2. Cover - p. iii 3. Title Page - p. iii 4. Copyright - p. iv 5. Table of Contents - p. iv 6. Contributors - p. xv 7. Preface - p. xix 8. Chapter 1 Role of pyridine and its privileged derivatives as anti-infective agents - p. 1 9. Chapter 2 Pyridine-based polymers and derivatives: Synthesis and applications - p. 43 10. Chapter 3 Synthetic strategies of functionalized pyridines and their therapeutic potential as multifunctional anti-Alzheimer's agents - p. 69 11. Chapter 4 Design, synthesis, and in vitro anticancer activity of thiophene substituted pyridine derivatives - p. 127 12. Chapter 5 The role of pyridine derivatives on the treatment of some complex diseases: A review - p. 143 13. Chapter 6 Pyridines in Alzheimer's disease therapy: Recent trends and advancements - p. 159 14. Chapter 7 Pyridine derivatives as anti-Alzheimer agents - p. 189 15. Chapter 8 Role of pyridines as enzyme inhibitors in medicinal chemistry - p. 207 16. Chapter 9 Contemporary development in the synthesis and biological applications of pyridine-based heterocyclic motifs - p. 253 17. Chapter 10 Synthesis of pyridine derivatives using multicomponent reactions - p. 299 18. Chapter 11 Recent green synthesis of pyridines and their fused systems catalyzed by nanocatalysts - p. 331 19. Chapter 12 Pyridine ring as an important scaffold in anticancer drugs - p. 375 20. Chapter 13 Recent developments in the synthesis of pyridine analogues as a potent anti-Alzheimer's therapeutic leads - p. 411 21. Chapter 14 Pyridine-based probes and chemosensors - p. 445 22. Chapter 15 Recent advances in catalytic synthesis of pyridine derivatives - p. 503 23. Chapter 16 Pyridine as a potent antimicrobial agent and its recent discoveries - p. 581 24. Chapter 17 Synthesis of pyridine derivatives for diverse biological activity profiles: A review - p. 605 25. Index - p. 625
Recent Developments in the Synthesis and Applications of Pyridines is a comprehensive handbook for organic chemists working on innovative approaches to the synthesis of pyridines. Written by scientists in both academia and industry and designed to be a standalone reference, the book features reviews, research results and case studies on synthetic methods and applications of pyridine-based chemotypes. The book will bridge the gap between industry and academia by presenting recent innovative approaches to the synthesis of pyridines, diverse application of pyridines in drug development, heterogeneous catalysis and material science, as well as benchtop to shelf narratives of pyridine-based compounds in the industry.
The role of computational chemistry in the development of pyridine-based bioactive molecules is also included. This reference is essential for researchers in organic chemistry both in academic and industrial settings, postgraduates in chemistry and medicinal chemistry.
1. Recent Developments in the Synthesis and Applications of Pyridines - p. iii 2. Cover - p. iii 3. Title Page - p. iii 4. Copyright - p. iv 5. Table of Contents - p. iv 6. Contributors - p. xv 7. Preface - p. xix 8. Chapter 1 Role of pyridine and its privileged derivatives as anti-infective agents - p. 1 9. Chapter 2 Pyridine-based polymers and derivatives: Synthesis and applications - p. 43 10. Chapter 3 Synthetic strategies of functionalized pyridines and their therapeutic potential as multifunctional anti-Alzheimer's agents - p. 69 11. Chapter 4 Design, synthesis, and in vitro anticancer activity of thiophene substituted pyridine derivatives - p. 127 12. Chapter 5 The role of pyridine derivatives on the treatment of some complex diseases: A review - p. 143 13. Chapter 6 Pyridines in Alzheimer's disease therapy: Recent trends and advancements - p. 159 14. Chapter 7 Pyridine derivatives as anti-Alzheimer agents - p. 189 15. Chapter 8 Role of pyridines as enzyme inhibitors in medicinal chemistry - p. 207 16. Chapter 9 Contemporary development in the synthesis and biological applications of pyridine-based heterocyclic motifs - p. 253 17. Chapter 10 Synthesis of pyridine derivatives using multicomponent reactions - p. 299 18. Chapter 11 Recent green synthesis of pyridines and their fused systems catalyzed by nanocatalysts - p. 331 19. Chapter 12 Pyridine ring as an important scaffold in anticancer drugs - p. 375 20. Chapter 13 Recent developments in the synthesis of pyridine analogues as a potent anti-Alzheimer's therapeutic leads - p. 411 21. Chapter 14 Pyridine-based probes and chemosensors - p. 445 22. Chapter 15 Recent advances in catalytic synthesis of pyridine derivatives - p. 503 23. Chapter 16 Pyridine as a potent antimicrobial agent and its recent discoveries - p. 581 24. Chapter 17 Synthesis of pyridine derivatives for diverse biological activity profiles: A review - p. 605 25. Index - p. 625
