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Descripción

This new volume of Methods in Cell Biology looks at receptor-receptor interactions, with sections on allosteric and effector interactions, crystallization and modeling, measuring receptor-receptor interactions and oligomerization in individual classes.

With cutting-edge material, this comprehensive collection is intended to guide researchers of receptor-receptor interactions for years to come.



  • Covers sections on allosteric and effector interactions, crystallization and modeling, measuring receptor-receptor interactions and oligomerization in individual classes
  • Chapters are written by experts in the field
  • Cutting-edge material

1. Cover image 2. Title page 3. Table of Contents 4. Series Page 5. Copyright 6. Contributors 7. Preface 8. Chapter 1. Spatial Intensity Distribution Analysis (SpIDA): A New Tool for Receptor Tyrosine Kinase Activation and Transactivation Quantification 9. Chapter 2. Dimerization of Nuclear Receptors 10. Chapter 3. Network Analysis to Uncover the Structural Communication in GPCRs 11. Chapter 4. Simulating G Protein-Coupled Receptors in Native-Like Membranes: From Monomers to Oligomers 12. Chapter 5. Structure-Based Molecular Modeling Approaches to GPCR Oligomerization 13. Chapter 6. Biochemical and Imaging Methods to Study Receptor Membrane Organization and Association with Lipid Rafts 14. Chapter 7. Serotonin Type 4 Receptor Dimers 15. Chapter 8. Bioluminescence Resonance Energy Transfer Methods to Study G Protein-Coupled Receptor–Receptor Tyrosine Kinase Heteroreceptor Complexes 16. Chapter 9. A Simple Method to Detect Allostery in GPCR Dimers 17. Chapter 10. Fluorescence Correlation Spectroscopy and Photon-Counting Histogram Analysis of Receptor–Receptor Interactions 18. Chapter 11. Monitoring Receptor Oligomerization by Line-Scan Fluorescence Cross-Correlation Spectroscopy 19. Chapter 12. Biochemical Assay of G Protein-Coupled Receptor Oligomerization: Adenosine A1 and Thromboxane A2 Receptors Form the Novel Functional Hetero-oligomer 20. Chapter 13. Oligomerization of Sweet and Bitter Taste Receptors 21. Chapter 14. Analysis of Receptor–Receptor Interaction by Combined Application of FRET and Microscopy 22. Chapter 15. Site-Specific Labeling of Genetically Encoded Azido Groups for Multicolor, Single-Molecule Fluorescence Imaging of GPCRs 23. Chapter 16. Analysis of EGF Receptor Oligomerization by Homo-FRET 24. Chapter 17. Detection of G Protein-Coupled Receptor (GPCR) Dimerization by Coimmunoprecipitation 25. Chapter 18. Lipid-Dependent GPCR Dimerization 26. Chapter 19. Monitoring Peripheral Protein Oligomerization on Biological Membranes 27. Chapter 20. Single-Molecule Imaging of Receptor–Receptor Interactions 28. Chapter 21. Visualization of TCR Nanoclusters via Immunogold Labeling, Freeze-Etching, and Surface Replication 29. Chapter 22. Identification of Multimolecular Complexes and Supercomplexes in Compartment-Selective Membrane Microdomains 30. Chapter 23. G Protein-Coupled Receptor Transactivation: From Molecules to Mice 31. Chapter 24. Crystallization of G Protein-Coupled Receptors 32. Index 33. Volumes in Series

Descripcion
Descripción

This new volume of Methods in Cell Biology looks at receptor-receptor interactions, with sections on allosteric and effector interactions, crystallization and modeling, measuring receptor-receptor interactions and oligomerization in individual classes.

With cutting-edge material, this comprehensive collection is intended to guide researchers of receptor-receptor interactions for years to come.



  • Covers sections on allosteric and effector interactions, crystallization and modeling, measuring receptor-receptor interactions and oligomerization in individual classes
  • Chapters are written by experts in the field
  • Cutting-edge material

1. Cover image 2. Title page 3. Table of Contents 4. Series Page 5. Copyright 6. Contributors 7. Preface 8. Chapter 1. Spatial Intensity Distribution Analysis (SpIDA): A New Tool for Receptor Tyrosine Kinase Activation and Transactivation Quantification 9. Chapter 2. Dimerization of Nuclear Receptors 10. Chapter 3. Network Analysis to Uncover the Structural Communication in GPCRs 11. Chapter 4. Simulating G Protein-Coupled Receptors in Native-Like Membranes: From Monomers to Oligomers 12. Chapter 5. Structure-Based Molecular Modeling Approaches to GPCR Oligomerization 13. Chapter 6. Biochemical and Imaging Methods to Study Receptor Membrane Organization and Association with Lipid Rafts 14. Chapter 7. Serotonin Type 4 Receptor Dimers 15. Chapter 8. Bioluminescence Resonance Energy Transfer Methods to Study G Protein-Coupled Receptor–Receptor Tyrosine Kinase Heteroreceptor Complexes 16. Chapter 9. A Simple Method to Detect Allostery in GPCR Dimers 17. Chapter 10. Fluorescence Correlation Spectroscopy and Photon-Counting Histogram Analysis of Receptor–Receptor Interactions 18. Chapter 11. Monitoring Receptor Oligomerization by Line-Scan Fluorescence Cross-Correlation Spectroscopy 19. Chapter 12. Biochemical Assay of G Protein-Coupled Receptor Oligomerization: Adenosine A1 and Thromboxane A2 Receptors Form the Novel Functional Hetero-oligomer 20. Chapter 13. Oligomerization of Sweet and Bitter Taste Receptors 21. Chapter 14. Analysis of Receptor–Receptor Interaction by Combined Application of FRET and Microscopy 22. Chapter 15. Site-Specific Labeling of Genetically Encoded Azido Groups for Multicolor, Single-Molecule Fluorescence Imaging of GPCRs 23. Chapter 16. Analysis of EGF Receptor Oligomerization by Homo-FRET 24. Chapter 17. Detection of G Protein-Coupled Receptor (GPCR) Dimerization by Coimmunoprecipitation 25. Chapter 18. Lipid-Dependent GPCR Dimerization 26. Chapter 19. Monitoring Peripheral Protein Oligomerization on Biological Membranes 27. Chapter 20. Single-Molecule Imaging of Receptor–Receptor Interactions 28. Chapter 21. Visualization of TCR Nanoclusters via Immunogold Labeling, Freeze-Etching, and Surface Replication 29. Chapter 22. Identification of Multimolecular Complexes and Supercomplexes in Compartment-Selective Membrane Microdomains 30. Chapter 23. G Protein-Coupled Receptor Transactivation: From Molecules to Mice 31. Chapter 24. Crystallization of G Protein-Coupled Receptors 32. Index 33. Volumes in Series

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