Regenerative Hepatology and Liver Transplantation is the second volume in the Regenerative and Transplant Medicine series. This volume is essential as no field in the biomedical sciences has more interest than organ transplantation regarding regenerative medicine, primarily because of the urgent need to improve transplant outcomes and increase transplantation rates is critical to treat the many patients suffering from liver disease.
The goal of this book is to bridge regenerative hepatology and transplant medicine, by illustrating the state of the art of clinical liver transplantation, as well as of the progress of regenerative medicine (RM) investigations aiming at the bioengineering, regeneration, and repair of the liver.
This volume is necessary and would be placed well in the current global trend toward increasing organ donation utilizing such cutting-edge technologies. Written by the world’s experts in the field of liver diseases, it is a perfect reference for transplant operators, researchers, regenerative medicine operators, tissue engineering operators, biotech operators, and those in academia, industry, and regulatory agencies working to advance the field.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Contributors - p. xiii 7. Section I. The liver and liver diseases - p. 1 8. Chapter 1. Prevalence of liver disease around the world - p. 3 9. Chapter 2. Viral hepatitis - p. 23 10. Chapter 3. Non-alcoholic steatohepatitis - p. 35 11. Chapter 4. Alcoholic liver disease - p. 55 12. Chapter 5. Liver fibrosis and cirrhosis - p. 71 13. Chapter 6. Biomarkers in liver disease and transplantation: Outlook for precision medicine - p. 81 14. Section II. Liver transplantation - p. 117 15. Chapter 7. Living donor liver transplantation - p. 119 16. Chapter 8. Small-for-size syndrome in liver transplantation - p. 129 17. Chapter 9. Clinical trials design and endpoints in liver transplantation - p. 135 18. Chapter 10. Oncologic liver transplantation: Transplant oncology - p. 149 19. Chapter 11. Management of hepatocellular carcinoma - p. 163 20. Section III. Cell transplantation - p. 201 21. Chapter 12. Human hepatocyte transplantation - p. 203 22. Chapter 13. Mesenchymal stem cell transplantation - p. 215 23. Chapter 14. Biliary tree stem cell transplantation - p. 225 24. Section IV. Liver preservation and machine perfusion - p. 245 25. Chapter 15. General principles of organ preservation in liver transplantation - p. 247 26. Chapter 16. Ischemia-reperfusion injury - p. 269 27. Section V. Regenerative medicine in liver disease and transplantation - p. 295 28. Chapter 17. Liver regeneration - p. 297 29. Chapter 18. Whole-liver bioengineering: The future of transplantation medicine - p. 307 30. Chapter 19. Nanotechnology application in liver transplantation - p. 337 31. Chapter 20. Acute liver failure and bioreactors/liver assist devices - p. 349 32. Chapter 21. Hepatobiliary organoids and large-scale expansion for regenerative therapies - p. 385 33. Chapter 22. Liver aging - p. 391 34. Index - p. 409
Regenerative Hepatology and Liver Transplantation is the second volume in the Regenerative and Transplant Medicine series. This volume is essential as no field in the biomedical sciences has more interest than organ transplantation regarding regenerative medicine, primarily because of the urgent need to improve transplant outcomes and increase transplantation rates is critical to treat the many patients suffering from liver disease.
The goal of this book is to bridge regenerative hepatology and transplant medicine, by illustrating the state of the art of clinical liver transplantation, as well as of the progress of regenerative medicine (RM) investigations aiming at the bioengineering, regeneration, and repair of the liver.
This volume is necessary and would be placed well in the current global trend toward increasing organ donation utilizing such cutting-edge technologies. Written by the world’s experts in the field of liver diseases, it is a perfect reference for transplant operators, researchers, regenerative medicine operators, tissue engineering operators, biotech operators, and those in academia, industry, and regulatory agencies working to advance the field.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Contributors - p. xiii 7. Section I. The liver and liver diseases - p. 1 8. Chapter 1. Prevalence of liver disease around the world - p. 3 9. Chapter 2. Viral hepatitis - p. 23 10. Chapter 3. Non-alcoholic steatohepatitis - p. 35 11. Chapter 4. Alcoholic liver disease - p. 55 12. Chapter 5. Liver fibrosis and cirrhosis - p. 71 13. Chapter 6. Biomarkers in liver disease and transplantation: Outlook for precision medicine - p. 81 14. Section II. Liver transplantation - p. 117 15. Chapter 7. Living donor liver transplantation - p. 119 16. Chapter 8. Small-for-size syndrome in liver transplantation - p. 129 17. Chapter 9. Clinical trials design and endpoints in liver transplantation - p. 135 18. Chapter 10. Oncologic liver transplantation: Transplant oncology - p. 149 19. Chapter 11. Management of hepatocellular carcinoma - p. 163 20. Section III. Cell transplantation - p. 201 21. Chapter 12. Human hepatocyte transplantation - p. 203 22. Chapter 13. Mesenchymal stem cell transplantation - p. 215 23. Chapter 14. Biliary tree stem cell transplantation - p. 225 24. Section IV. Liver preservation and machine perfusion - p. 245 25. Chapter 15. General principles of organ preservation in liver transplantation - p. 247 26. Chapter 16. Ischemia-reperfusion injury - p. 269 27. Section V. Regenerative medicine in liver disease and transplantation - p. 295 28. Chapter 17. Liver regeneration - p. 297 29. Chapter 18. Whole-liver bioengineering: The future of transplantation medicine - p. 307 30. Chapter 19. Nanotechnology application in liver transplantation - p. 337 31. Chapter 20. Acute liver failure and bioreactors/liver assist devices - p. 349 32. Chapter 21. Hepatobiliary organoids and large-scale expansion for regenerative therapies - p. 385 33. Chapter 22. Liver aging - p. 391 34. Index - p. 409
