Readable and highly illustrated, Robbins and Cotran Pathologic Basis of Disease, 10th Edition presents an in-depth, state-of-the-art overview of human diseases and their cellular and molecular basis. This best-selling text delivers the latest, most essential pathology knowledge in a readable, interesting manner, ensuring optimal understanding of the latest basic science and clinical content. More than 1,000 high-quality photographs and full-color illustrations highlight new information in molecular biology, disease classifications, new drugs and drug therapies, and much more. This superb learning package also includes an enhanced eBook with a full complement of ancillary content on Student Consult.
1. Cover image - p. i 2. Table of Contents - p. i 3. Endsheet - p. IFC2 4. Copyright - p. iv 5. Dedication - p. v 6. Contributors - p. vi 7. Preface - p. viii 8. Acknowledgments - p. x 9. Contents - p. xi 10. Chapter 1: The Cell as a Unit of Health and Disease - p. 1 11. Chapter 2: Cell Injury, Cell Death, and Adaptations - p. 33 12. Chapter 3: Inflammation and Repair - p. 71 13. Chapter 4: Hemodynamic Disorders, Thromboembolic Disease, and Shock - p. 115 14. Chapter 5: Genetic Disorders - p. 141 15. Genes and Human Diseases - p. 141 16. Mendelian Disorders - p. 144 17. Complex Multigenic Disorders - p. 163 18. Chromosomal Disorders - p. 164 19. Single-Gene Disorders With Nonclassic Inheritance - p. 173 20. Molecular Genetic Diagnosis - p. 180 21. Acknowledgment - p. 187 22. Chapter 6: Diseases of the Immune System - p. 189 23. The Normal Immune Response - p. 190 24. Hypersensitivity: Immunologically Mediated Tissue Injury - p. 204 25. Autoimmune Diseases - p. 215 26. Rejection of Tissue Transplants - p. 234 27. Immunodeficiency Diseases - p. 240 28. Amyloidosis - p. 259 29. Chapter 7: Neoplasia - p. 267 30. Nomenclature - p. 268 31. Characteristics of Benign and Malignant Neoplasms - p. 270 32. Epidemiology of Cancer - p. 277 33. Molecular Basis of Cancer: Role of Genetic and Epigenetic Alterations - p. 281 34. Carcinogenic Agents and Their Cellular Interactions - p. 320 35. Clinical Aspects of Neoplasia - p. 328 36. Chapter 8: Infectious Diseases - p. 339 37. General Principles of Microbial Pathogenesis - p. 339 38. Viral Infections - p. 349 39. Bacterial Infections - p. 359 40. Fungal Infections - p. 383 41. Parasitic Infections - p. 388 42. Sexually Transmitted Infections - p. 399 43. Emerging Infectious Diseases - p. 400 44. Special Techniques for Diagnosing Infectious Agents - p. 401 45. Chapter 9: Environmental and Nutritional Diseases - p. 405 46. Chapter 10: Diseases of Infancy and ChildhoodaaThe prior contributions of Dr. Anirban Maitra to this chapter are gratefully acknowledged. - p. 453 47. Chapter 11: Blood Vessels - p. 485 48. Chapter 12: The Heart - p. 527 49. Cardiac Structure and Specializations - p. 528 50. Overview of Cardiac Pathophysiology - p. 529 51. Heart Failure - p. 530 52. Cardiac Development - p. 534 53. Congenital Heart Disease - p. 534 54. Ischemic Heart Disease - p. 542 55. Arrhythmias - p. 554 56. Hypertensive Heart Disease - p. 555 57. Valvular Heart Disease - p. 557 58. Cardiomyopathies - p. 567 59. Pericardial Disease - p. 577 60. Tumors of the Heart - p. 579 61. Cardiac Transplantation - p. 580 62. Cardiac Devices - p. 580 63. Chapter 13: Diseases of White Blood Cells, Lymph Nodes, Spleen, and Thymus - p. 583 64. Normal Hematopoiesis - p. 584 65. Disorders of White Cells - p. 586 66. Spleen - p. 628 67. Thymus - p. 631 68. Chapter 14: Red Blood Cell and Bleeding Disorders - p. 635 69. Chapter 15: The Lung - p. 673 70. Congenital Anomalies - p. 674 71. Atelectasis (Collapse) - p. 674 72. Pulmonary Edema - p. 675 73. Acute Lung Injury and Acute Respiratory Distress Syndrome (Diffuse Alveolar Damage) - p. 676 74. Obstructive and Restrictive Lung Diseases - p. 678 75. Obstructive Lung Diseases - p. 678 76. Chronic Diffuse Interstitial (Restrictive) Diseases - p. 688 77. Diseases of Vascular Origin - p. 700 78. Pulmonary Infections - p. 705 79. Lung Transplantation - p. 714 80. Tumors - p. 715 81. Pleura - p. 725 82. Chapter 16: Head and Neck - p. 731 83. Chapter 17: The Gastrointestinal Tract - p. 753 84. Congenital Abnormalities - p. 754 85. Esophagus - p. 757 86. Stomach - p. 764 87. Small Intestine and Colon - p. 780 88. Peritoneal Cavity - p. 820 89. Congenital Abnormalities - p. 820 90. Esophagus - p. 820 91. Stomach - p. 821 92. Small Intestine and Colon - p. 821 93. Peritoneal Cavity - p. 822 94. Chapter 18: Liver and Gallbladder - p. 823 95. The Liver and Bile Ducts - p. 823 96. Gallbladder - p. 872 97. Chapter 19: The Pancreas - p. 881 98. Chapter 20: The Kidney - p. 895 99. Clinical Manifestations of Renal Diseases - p. 896 100. Glomerular Diseases - p. 897 101. Tubular and Interstitial Diseases - p. 924 102. Vascular Diseases - p. 935 103. Congenital and Developmental Anomalies - p. 940 104. Cystic Diseases of the Kidney - p. 941 105. Urinary Tract Obstruction (Obstructive Uropathy) - p. 945 106. Urolithiasis (Renal Calculi, Stones) - p. 947 107. Neoplasms of the Kidney - p. 948 108. Chapter 21: The Lower Urinary Tract and Male Genital System - p. 953 109. Chapter 22: The Female Genital Tract - p. 985 110. Chapter 23: The Breast - p. 1037 111. Chapter 24: The Endocrine System - p. 1065 112. Pituitary Gland - p. 1066 113. Thyroid Gland - p. 1075 114. Parathyroid Glands - p. 1093 115. The Endocrine Pancreas - p. 1097 116. Adrenal Glands - p. 1114 117. Multiple Endocrine Neoplasia Syndromes - p. 1129 118. Pineal Gland - p. 1130 119. Chapter 25: The Skin - p. 1133 120. Chapter 26: Bones, Joints, and Soft Tissue Tumors - p. 1171 121. Chapter 27: Peripheral Nerves and Skeletal Muscles - p. 1217 122. Chapter 28: The Central Nervous System - p. 1241 123. Cellular Pathology of the Central Nervous System - p. 1242 124. Cerebral Edema, Hydrocephalus, Raised Intracranial Pressure, and Herniation - p. 1244 125. Malformations and Developmental Disorders - p. 1245 126. Perinatal Brain Injury - p. 1248 127. Trauma - p. 1249 128. Cerebrovascular Disease - p. 1253 129. Infections - p. 1261 130. Demyelinating Diseases - p. 1269 131. Neurodegenerative Diseases - p. 1273 132. Genetic Metabolic Diseases - p. 1289 133. Toxic and Acquired Metabolic Diseases - p. 1291 134. Tumors - p. 1293 135. Acknowledgment - p. 1303 136. Chapter 29: The Eye - p. 1305 137. Index - p. 1329
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Readable and highly illustrated, Robbins and Cotran Pathologic Basis of Disease, 10th Edition presents an in-depth, state-of-the-art overview of human diseases and their cellular and molecular basis. This best-selling text delivers the latest, most essential pathology knowledge in a readable, interesting manner, ensuring optimal understanding of the latest basic science and clinical content. More than 1,000 high-quality photographs and full-color illustrations highlight new information in molecular biology, disease classifications, new drugs and drug therapies, and much more. This superb learning package also includes an enhanced eBook with a full complement of ancillary content on Student Consult.
1. Cover image - p. i 2. Table of Contents - p. i 3. Endsheet - p. IFC2 4. Copyright - p. iv 5. Dedication - p. v 6. Contributors - p. vi 7. Preface - p. viii 8. Acknowledgments - p. x 9. Contents - p. xi 10. Chapter 1: The Cell as a Unit of Health and Disease - p. 1 11. Chapter 2: Cell Injury, Cell Death, and Adaptations - p. 33 12. Chapter 3: Inflammation and Repair - p. 71 13. Chapter 4: Hemodynamic Disorders, Thromboembolic Disease, and Shock - p. 115 14. Chapter 5: Genetic Disorders - p. 141 15. Genes and Human Diseases - p. 141 16. Mendelian Disorders - p. 144 17. Complex Multigenic Disorders - p. 163 18. Chromosomal Disorders - p. 164 19. Single-Gene Disorders With Nonclassic Inheritance - p. 173 20. Molecular Genetic Diagnosis - p. 180 21. Acknowledgment - p. 187 22. Chapter 6: Diseases of the Immune System - p. 189 23. The Normal Immune Response - p. 190 24. Hypersensitivity: Immunologically Mediated Tissue Injury - p. 204 25. Autoimmune Diseases - p. 215 26. Rejection of Tissue Transplants - p. 234 27. Immunodeficiency Diseases - p. 240 28. Amyloidosis - p. 259 29. Chapter 7: Neoplasia - p. 267 30. Nomenclature - p. 268 31. Characteristics of Benign and Malignant Neoplasms - p. 270 32. Epidemiology of Cancer - p. 277 33. Molecular Basis of Cancer: Role of Genetic and Epigenetic Alterations - p. 281 34. Carcinogenic Agents and Their Cellular Interactions - p. 320 35. Clinical Aspects of Neoplasia - p. 328 36. Chapter 8: Infectious Diseases - p. 339 37. General Principles of Microbial Pathogenesis - p. 339 38. Viral Infections - p. 349 39. Bacterial Infections - p. 359 40. Fungal Infections - p. 383 41. Parasitic Infections - p. 388 42. Sexually Transmitted Infections - p. 399 43. Emerging Infectious Diseases - p. 400 44. Special Techniques for Diagnosing Infectious Agents - p. 401 45. Chapter 9: Environmental and Nutritional Diseases - p. 405 46. Chapter 10: Diseases of Infancy and ChildhoodaaThe prior contributions of Dr. Anirban Maitra to this chapter are gratefully acknowledged. - p. 453 47. Chapter 11: Blood Vessels - p. 485 48. Chapter 12: The Heart - p. 527 49. Cardiac Structure and Specializations - p. 528 50. Overview of Cardiac Pathophysiology - p. 529 51. Heart Failure - p. 530 52. Cardiac Development - p. 534 53. Congenital Heart Disease - p. 534 54. Ischemic Heart Disease - p. 542 55. Arrhythmias - p. 554 56. Hypertensive Heart Disease - p. 555 57. Valvular Heart Disease - p. 557 58. Cardiomyopathies - p. 567 59. Pericardial Disease - p. 577 60. Tumors of the Heart - p. 579 61. Cardiac Transplantation - p. 580 62. Cardiac Devices - p. 580 63. Chapter 13: Diseases of White Blood Cells, Lymph Nodes, Spleen, and Thymus - p. 583 64. Normal Hematopoiesis - p. 584 65. Disorders of White Cells - p. 586 66. Spleen - p. 628 67. Thymus - p. 631 68. Chapter 14: Red Blood Cell and Bleeding Disorders - p. 635 69. Chapter 15: The Lung - p. 673 70. Congenital Anomalies - p. 674 71. Atelectasis (Collapse) - p. 674 72. Pulmonary Edema - p. 675 73. Acute Lung Injury and Acute Respiratory Distress Syndrome (Diffuse Alveolar Damage) - p. 676 74. Obstructive and Restrictive Lung Diseases - p. 678 75. Obstructive Lung Diseases - p. 678 76. Chronic Diffuse Interstitial (Restrictive) Diseases - p. 688 77. Diseases of Vascular Origin - p. 700 78. Pulmonary Infections - p. 705 79. Lung Transplantation - p. 714 80. Tumors - p. 715 81. Pleura - p. 725 82. Chapter 16: Head and Neck - p. 731 83. Chapter 17: The Gastrointestinal Tract - p. 753 84. Congenital Abnormalities - p. 754 85. Esophagus - p. 757 86. Stomach - p. 764 87. Small Intestine and Colon - p. 780 88. Peritoneal Cavity - p. 820 89. Congenital Abnormalities - p. 820 90. Esophagus - p. 820 91. Stomach - p. 821 92. Small Intestine and Colon - p. 821 93. Peritoneal Cavity - p. 822 94. Chapter 18: Liver and Gallbladder - p. 823 95. The Liver and Bile Ducts - p. 823 96. Gallbladder - p. 872 97. Chapter 19: The Pancreas - p. 881 98. Chapter 20: The Kidney - p. 895 99. Clinical Manifestations of Renal Diseases - p. 896 100. Glomerular Diseases - p. 897 101. Tubular and Interstitial Diseases - p. 924 102. Vascular Diseases - p. 935 103. Congenital and Developmental Anomalies - p. 940 104. Cystic Diseases of the Kidney - p. 941 105. Urinary Tract Obstruction (Obstructive Uropathy) - p. 945 106. Urolithiasis (Renal Calculi, Stones) - p. 947 107. Neoplasms of the Kidney - p. 948 108. Chapter 21: The Lower Urinary Tract and Male Genital System - p. 953 109. Chapter 22: The Female Genital Tract - p. 985 110. Chapter 23: The Breast - p. 1037 111. Chapter 24: The Endocrine System - p. 1065 112. Pituitary Gland - p. 1066 113. Thyroid Gland - p. 1075 114. Parathyroid Glands - p. 1093 115. The Endocrine Pancreas - p. 1097 116. Adrenal Glands - p. 1114 117. Multiple Endocrine Neoplasia Syndromes - p. 1129 118. Pineal Gland - p. 1130 119. Chapter 25: The Skin - p. 1133 120. Chapter 26: Bones, Joints, and Soft Tissue Tumors - p. 1171 121. Chapter 27: Peripheral Nerves and Skeletal Muscles - p. 1217 122. Chapter 28: The Central Nervous System - p. 1241 123. Cellular Pathology of the Central Nervous System - p. 1242 124. Cerebral Edema, Hydrocephalus, Raised Intracranial Pressure, and Herniation - p. 1244 125. Malformations and Developmental Disorders - p. 1245 126. Perinatal Brain Injury - p. 1248 127. Trauma - p. 1249 128. Cerebrovascular Disease - p. 1253 129. Infections - p. 1261 130. Demyelinating Diseases - p. 1269 131. Neurodegenerative Diseases - p. 1273 132. Genetic Metabolic Diseases - p. 1289 133. Toxic and Acquired Metabolic Diseases - p. 1291 134. Tumors - p. 1293 135. Acknowledgment - p. 1303 136. Chapter 29: The Eye - p. 1305 137. Index - p. 1329
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