Role of Nutrigenomics in Modern-day Healthcare and Drug Discovery presents novel insights into how these tools can be applied in the study of nutrient-gene interaction for the management of certain disease conditions without using synthetic drugs or other treatments that come with side effects. Divided into three parts, Part I presents chapters that give background information of the subject while laying a framework for other chapters to follow. Part II presents chapters that discuss the role of nutrigenomics in healthcare, while Part III presents chapters that discuss the role of nutrigenomics in modern day drug discovery.
Written by a global team of experts from key institutions around the world, this book is useful for drug developers, medicinal chemists, public health scientists, molecular biologists, biochemists, toxicologists and food scientists.
1. Title of Book - p. Cover 2. Cover image - p. Cover 3. Title page - p. ii 4. Table of Contents - p. iv 5. Copyright - p. iv 6. Contributors - p. xi 7. Section A: Foundational information - p. xvii 8. 1. General principles in nutrigenomics and nutrigenetics - p. 5 9. 2. Nutrigenomics and nutrigenetics: Importance in health and diseases - p. 22 10. 3. Nutrigenomics research: Methods and applications - p. 40 11. Section B: Role of nutrigenomics in healthcare - p. 82 12. 4. Nutrigenomics of type 2 diabetes: Gene–diet interactions - p. 85 13. 5. Role of nutrigenomics in diabetes care and prevention - p. 119 14. 6. Role of nutrigenomics in obesity, hypertension, and cardiovascular diseases - p. 140 15. 7. Nutrigenomics in the management and prevention of malnutrition, stunting, and other nutritional disorders - p. 147 16. 8. Nutrigenomics in the management and prevention of cancer - p. 177 17. 9. Nutrigenomics in the management and prevention of metabolic disorders - p. 221 18. Section C: Nutrigenomics and drug discovery - p. 274 19. 10. Roles of nutrigenomics in drug discovery and development - p. 277 20. 11. Bioactive compounds of nutrigenomic importance - p. 317 21. 12. Bioactive compounds in the management of nutritional disorders - p. 348 22. 13. Dietary compounds as inhibitors of DNA methyltransferases - p. 359 23. 14. Bioactive compounds in diabetes care and prevention - p. 393 24. 15. Bioactive compounds in cancer care and prevention - p. 439 25. 16. Role of medicinal plants and their bioactive compounds in obesity, hypertension, and cardiovascular diseases - p. 483 26. 17. Bioactive compounds for metabolic diseases - p. 521 27. 18. Applications of nanotechnology in nutrigenomics - p. 547 28. 19. Regulations and ethical considerations in nutrigenomics research - p. 557 29. Index - p. 567
Role of Nutrigenomics in Modern-day Healthcare and Drug Discovery presents novel insights into how these tools can be applied in the study of nutrient-gene interaction for the management of certain disease conditions without using synthetic drugs or other treatments that come with side effects. Divided into three parts, Part I presents chapters that give background information of the subject while laying a framework for other chapters to follow. Part II presents chapters that discuss the role of nutrigenomics in healthcare, while Part III presents chapters that discuss the role of nutrigenomics in modern day drug discovery.
Written by a global team of experts from key institutions around the world, this book is useful for drug developers, medicinal chemists, public health scientists, molecular biologists, biochemists, toxicologists and food scientists.
1. Title of Book - p. Cover 2. Cover image - p. Cover 3. Title page - p. ii 4. Table of Contents - p. iv 5. Copyright - p. iv 6. Contributors - p. xi 7. Section A: Foundational information - p. xvii 8. 1. General principles in nutrigenomics and nutrigenetics - p. 5 9. 2. Nutrigenomics and nutrigenetics: Importance in health and diseases - p. 22 10. 3. Nutrigenomics research: Methods and applications - p. 40 11. Section B: Role of nutrigenomics in healthcare - p. 82 12. 4. Nutrigenomics of type 2 diabetes: Gene–diet interactions - p. 85 13. 5. Role of nutrigenomics in diabetes care and prevention - p. 119 14. 6. Role of nutrigenomics in obesity, hypertension, and cardiovascular diseases - p. 140 15. 7. Nutrigenomics in the management and prevention of malnutrition, stunting, and other nutritional disorders - p. 147 16. 8. Nutrigenomics in the management and prevention of cancer - p. 177 17. 9. Nutrigenomics in the management and prevention of metabolic disorders - p. 221 18. Section C: Nutrigenomics and drug discovery - p. 274 19. 10. Roles of nutrigenomics in drug discovery and development - p. 277 20. 11. Bioactive compounds of nutrigenomic importance - p. 317 21. 12. Bioactive compounds in the management of nutritional disorders - p. 348 22. 13. Dietary compounds as inhibitors of DNA methyltransferases - p. 359 23. 14. Bioactive compounds in diabetes care and prevention - p. 393 24. 15. Bioactive compounds in cancer care and prevention - p. 439 25. 16. Role of medicinal plants and their bioactive compounds in obesity, hypertension, and cardiovascular diseases - p. 483 26. 17. Bioactive compounds for metabolic diseases - p. 521 27. 18. Applications of nanotechnology in nutrigenomics - p. 547 28. 19. Regulations and ethical considerations in nutrigenomics research - p. 557 29. Index - p. 567