Secondary Metabolites in Stress and Disease Management: A Natural Alternative details the sources and diversity of microbial and plant secondary metabolites, the methods used for their detection and extraction, their novel applications in disease management, and inclusion in mainstream therapy. Organized into three main sections, the book begins by discussing the potential of microbes, plants, microalgae, and cyanobacteria as valuable sources of secondary metabolites, their role and mechanisms of action in symbiotic and competitive interactions, extractions and purification strategies, and the means to maximize their production. The book goes on to explore the utility of secondary metabolites in mitigating plant stress and their therapeutic impact on human health management. With contributions from experts in the field, Secondary Metabolites in Stress and Disease Management is a useful interdisciplinary resource for researchers, professors, graduate and postgraduate students, and industry professionals studying applied microbiology, biotechnology, biochemistry, pharmacology, and plant science.
1. Introduction - p. xxiii 2. I: Diversity and production strategies - p. xxv 3. Chapter 1. Secondary metabolites from plants - p. 3 4. Chapter 2. Microbial secondary metabolites - p. 27 5. Chapter 3. Microalgae as a rich source of secondary metabolites for food, feed, and pharmaceutical applications - p. 53 6. Chapter 4. Cyanobacteria as a source of secondary metabolites - p. 99 7. Chapter 5. Exploring the untapped reservoir of secondary metabolites in the Indian subcontinent - p. 123 8. Chapter 6. Extraction, purification, and identification strategies - p. 163 9. Chapter 7. Genetic engineering as a means to maximize secondary metabolite production - p. 195 10. Chapter 8. Enhanced production of medicinally valuable plant secondary metabolites through in vitro techniques - p. 241 11. Chapter 9. Harnessing bioinformatics for secondary metabolite discovery and analysis - p. 261 12. II: Role of secondary metabolites in plant stress management - p. 279 13. Chapter 10. Harnessing rhizospheric interactions for root disease control in plants - p. 289 14. Chapter 11. Influence of environmental stress on secondary metabolite production in plants - p. 315 15. Chapter 12. Plant–fungal interactions and secondary metabolites - p. 329 16. Chapter 13. Role of secondary metabolites in plant defense against bacterial and viral pathogens - p. 357 17. Chapter 14. Nature’s defense: the role of secondary metabolites in combating herbivory - p. 379 18. III: Role of secondary metabolites in human health - p. 389 19. Chapter 15. Secondary metabolites for improvement of human health - p. 395 20. Chapter 16. Role of secondary metabolites in neurodegenerative disorders - p. 421 21. Chapter 17. Potential application of secondary metabolites in cancer management - p. 443 22. Chapter 18. Potential application of secondary metabolites in diabetes - p. 475 23. Chapter 19. Therapeutic outcome of secondary metabolites against contagious and noncontagious human diseases - p. 519 24. Chapter 20. Therapeutic potential of Indian medicinal plants: a recent progress - p. 537 25. Chapter 21. Clinical research of indigenous medicinal florae and their pharmaceutical formulation for unlocking the management of COVID-19 - p. 575 26. Index - p. 597
Secondary Metabolites in Stress and Disease Management: A Natural Alternative details the sources and diversity of microbial and plant secondary metabolites, the methods used for their detection and extraction, their novel applications in disease management, and inclusion in mainstream therapy. Organized into three main sections, the book begins by discussing the potential of microbes, plants, microalgae, and cyanobacteria as valuable sources of secondary metabolites, their role and mechanisms of action in symbiotic and competitive interactions, extractions and purification strategies, and the means to maximize their production. The book goes on to explore the utility of secondary metabolites in mitigating plant stress and their therapeutic impact on human health management. With contributions from experts in the field, Secondary Metabolites in Stress and Disease Management is a useful interdisciplinary resource for researchers, professors, graduate and postgraduate students, and industry professionals studying applied microbiology, biotechnology, biochemistry, pharmacology, and plant science.
1. Introduction - p. xxiii 2. I: Diversity and production strategies - p. xxv 3. Chapter 1. Secondary metabolites from plants - p. 3 4. Chapter 2. Microbial secondary metabolites - p. 27 5. Chapter 3. Microalgae as a rich source of secondary metabolites for food, feed, and pharmaceutical applications - p. 53 6. Chapter 4. Cyanobacteria as a source of secondary metabolites - p. 99 7. Chapter 5. Exploring the untapped reservoir of secondary metabolites in the Indian subcontinent - p. 123 8. Chapter 6. Extraction, purification, and identification strategies - p. 163 9. Chapter 7. Genetic engineering as a means to maximize secondary metabolite production - p. 195 10. Chapter 8. Enhanced production of medicinally valuable plant secondary metabolites through in vitro techniques - p. 241 11. Chapter 9. Harnessing bioinformatics for secondary metabolite discovery and analysis - p. 261 12. II: Role of secondary metabolites in plant stress management - p. 279 13. Chapter 10. Harnessing rhizospheric interactions for root disease control in plants - p. 289 14. Chapter 11. Influence of environmental stress on secondary metabolite production in plants - p. 315 15. Chapter 12. Plant–fungal interactions and secondary metabolites - p. 329 16. Chapter 13. Role of secondary metabolites in plant defense against bacterial and viral pathogens - p. 357 17. Chapter 14. Nature’s defense: the role of secondary metabolites in combating herbivory - p. 379 18. III: Role of secondary metabolites in human health - p. 389 19. Chapter 15. Secondary metabolites for improvement of human health - p. 395 20. Chapter 16. Role of secondary metabolites in neurodegenerative disorders - p. 421 21. Chapter 17. Potential application of secondary metabolites in cancer management - p. 443 22. Chapter 18. Potential application of secondary metabolites in diabetes - p. 475 23. Chapter 19. Therapeutic outcome of secondary metabolites against contagious and noncontagious human diseases - p. 519 24. Chapter 20. Therapeutic potential of Indian medicinal plants: a recent progress - p. 537 25. Chapter 21. Clinical research of indigenous medicinal florae and their pharmaceutical formulation for unlocking the management of COVID-19 - p. 575 26. Index - p. 597
