In this issue of Clinics in Chest Medicine, guest editors Dr. John P. Reilly brings his considerable expertise to the topic of Sepsis. Leading experts provide in-depth discussions on fluids, vasoactives, and resusitation targets in septic shock; beyond lactate: biomarkers in sepsis; principals of antimicrobial administration in sepsis; steroids in sepsis; pediatric sepsis; immunology of sepsis; and more.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Defining Sepsis: Past, Present, and Future - p. 1 9. Global Sepsis Epidemiology - p. 17 10. Resuscitation Targets, Fluids, and Vasoactives in Septic Shock - p. 33 11. When and How Much? Steroids in Sepsis - p. 45 12. Pediatric Sepsis: Evolving Subphenotypes, Overlap Syndromes, and the Path to Precision Therapies - p. 57 13. Immunology of Sepsis - p. 67 14. Microcirculatory Dysfunction in Sepsis - p. 83 15. Utility of Animal Models of Pneumonia and Sepsis - p. 105 16. The Gut Microbiome and Short-Chain Fatty Acid Metabolites in Sepsis - p. 119 17. Neuroimmune Mechanisms Transforming Acute Injury to Long-Term Brain Dysfunction After Sepsis - p. 129 18. Pathophysiology and Management of Sepsis-associated Acute Kidney Injury - p. 143 19. Long-Term Outcomes After Sepsis: Chronic Disease Management as a New Area of Focus? - p. 157
In this issue of Clinics in Chest Medicine, guest editors Dr. John P. Reilly brings his considerable expertise to the topic of Sepsis. Leading experts provide in-depth discussions on fluids, vasoactives, and resusitation targets in septic shock; beyond lactate: biomarkers in sepsis; principals of antimicrobial administration in sepsis; steroids in sepsis; pediatric sepsis; immunology of sepsis; and more.
1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Defining Sepsis: Past, Present, and Future - p. 1 9. Global Sepsis Epidemiology - p. 17 10. Resuscitation Targets, Fluids, and Vasoactives in Septic Shock - p. 33 11. When and How Much? Steroids in Sepsis - p. 45 12. Pediatric Sepsis: Evolving Subphenotypes, Overlap Syndromes, and the Path to Precision Therapies - p. 57 13. Immunology of Sepsis - p. 67 14. Microcirculatory Dysfunction in Sepsis - p. 83 15. Utility of Animal Models of Pneumonia and Sepsis - p. 105 16. The Gut Microbiome and Short-Chain Fatty Acid Metabolites in Sepsis - p. 119 17. Neuroimmune Mechanisms Transforming Acute Injury to Long-Term Brain Dysfunction After Sepsis - p. 129 18. Pathophysiology and Management of Sepsis-associated Acute Kidney Injury - p. 143 19. Long-Term Outcomes After Sepsis: Chronic Disease Management as a New Area of Focus? - p. 157
