Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women.
1. Introduction to Sex Differences in Cardiovascular Physiology - p. xv 2. Part I: Sex Steroid Receptors - p. xvii 3. Chapter 1: Androgens and Cardiovascular Diseases in Women - p. xvii 4. Chapter 2: Estrogen Receptor Signaling and Cardiovascular Function - p. 12 5. Chapter 3: The Protective Role of Estrogen and Brain Estrogen Receptors in the Pathogenesis of Hypertension - p. 22 6. Chapter 4: Sex Differences in Cerebral Ischemia - p. 39 7. Part II: Sex Differences in Hypertension - p. 59 8. Chapter 5: Sex Differences in the Central Control of Sodium Appetite and Blood Pressure - p. 59 9. Chapter 6: Sex Differences in the Role of the Angiotensin Type 2 Receptor in the Regulation of Blood Pressure - p. 71 10. Chapter 7: Regulation of Postmenopausal Hypertension - p. 103 11. Part III: Preeclampsia and Long-Term Consequences - p. 118 12. Chapter 8: Preeclampsia-Spectrum Hypertensive Disorders of Pregnancy: Gestational Hypertension, Preeclampsia, Eclampsia, Chronic Hypertension, and HELLP Syndrome - p. 118 13. Chapter 9: Preeclampsia: Cardiovascular and Renal Risks During and After Pregnancy - p. 136 14. Chapter 10: The Cerebral Circulation During Pregnancy and Preeclampsia - p. 147 15. Part IV: Role of Sex and Atherosclerosis - p. 163 16. Chapter 11: Sex Differences and the Role of the Renin-Angiotensin System in Atherosclerosis and Abdominal Aortic Aneurysms - p. 163 17. Chapter 12: Sex Differences in Coronary Artery Disease - p. 184 18. Part V: Role of Sex Difference in Autoimmunity and Inflammation - p. 201 19. Chapter 13: The Role of Sex Differences in Inflammation and Autoimmune Diseases - p. 201 20. Chapter 14: Autoimmunity, Estrogen, and Lupus - p. 217 21. Chapter 15: Sex Differences in Autoimmune Type-1 Diabetes - p. 237 22. Part VI: Sex Differences in Cardiac Function and Remodeling - p. 249 23. Chapter 16: Sex Differences in Developmental Origins of Cardiovascular Disease - p. 249 24. Chapter 17: Sex Specific Mechanisms of Myocardial Hypertrophy and Heart Failure - p. 289 25. Part VII: Sex Steroids and Cardiovascular Disease, Men Versus Women - p. 318 26. Chapter 18: Benefits and Risks of Testosterone Therapy in Men With Testosterone Deficiency - p. 318 27. Chapter 19: Sex, Age, and Neurovascular Control - p. 354 28. Index - p. 367
Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women.
1. Introduction to Sex Differences in Cardiovascular Physiology - p. xv 2. Part I: Sex Steroid Receptors - p. xvii 3. Chapter 1: Androgens and Cardiovascular Diseases in Women - p. xvii 4. Chapter 2: Estrogen Receptor Signaling and Cardiovascular Function - p. 12 5. Chapter 3: The Protective Role of Estrogen and Brain Estrogen Receptors in the Pathogenesis of Hypertension - p. 22 6. Chapter 4: Sex Differences in Cerebral Ischemia - p. 39 7. Part II: Sex Differences in Hypertension - p. 59 8. Chapter 5: Sex Differences in the Central Control of Sodium Appetite and Blood Pressure - p. 59 9. Chapter 6: Sex Differences in the Role of the Angiotensin Type 2 Receptor in the Regulation of Blood Pressure - p. 71 10. Chapter 7: Regulation of Postmenopausal Hypertension - p. 103 11. Part III: Preeclampsia and Long-Term Consequences - p. 118 12. Chapter 8: Preeclampsia-Spectrum Hypertensive Disorders of Pregnancy: Gestational Hypertension, Preeclampsia, Eclampsia, Chronic Hypertension, and HELLP Syndrome - p. 118 13. Chapter 9: Preeclampsia: Cardiovascular and Renal Risks During and After Pregnancy - p. 136 14. Chapter 10: The Cerebral Circulation During Pregnancy and Preeclampsia - p. 147 15. Part IV: Role of Sex and Atherosclerosis - p. 163 16. Chapter 11: Sex Differences and the Role of the Renin-Angiotensin System in Atherosclerosis and Abdominal Aortic Aneurysms - p. 163 17. Chapter 12: Sex Differences in Coronary Artery Disease - p. 184 18. Part V: Role of Sex Difference in Autoimmunity and Inflammation - p. 201 19. Chapter 13: The Role of Sex Differences in Inflammation and Autoimmune Diseases - p. 201 20. Chapter 14: Autoimmunity, Estrogen, and Lupus - p. 217 21. Chapter 15: Sex Differences in Autoimmune Type-1 Diabetes - p. 237 22. Part VI: Sex Differences in Cardiac Function and Remodeling - p. 249 23. Chapter 16: Sex Differences in Developmental Origins of Cardiovascular Disease - p. 249 24. Chapter 17: Sex Specific Mechanisms of Myocardial Hypertrophy and Heart Failure - p. 289 25. Part VII: Sex Steroids and Cardiovascular Disease, Men Versus Women - p. 318 26. Chapter 18: Benefits and Risks of Testosterone Therapy in Men With Testosterone Deficiency - p. 318 27. Chapter 19: Sex, Age, and Neurovascular Control - p. 354 28. Index - p. 367
