Single-Cell Omics: Volume 1: Technological Advances and Applications provides the latest technological developments and applications of single-cell technologies in the field of biomedicine. In the current era of precision medicine, the single-cell omics technology is highly promising due to its potential in diagnosis, prognosis and therapeutics. Sections in the book cover single-cell omics research and applications, diverse technologies applied in the topic, such as pangenomics, metabolomics, and multi-omics of single cells, data analysis, and several applications of single-cell omics within the biomedical field, for example in cancer, metabolic and neuro diseases, immunology, pharmacogenomics, personalized medicine and reproductive health.
This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and members of the biomedical field who are interested in understanding more about single-cell omics and its potential for research and diagnosis.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xix 6. About the Editors - p. xxi 7. Preface - p. xxiii 8. Section I: Overview of Single-Cell Omics - p. xxiv 9. Chapter 1: Single-Cell Omics: An Overview - p. xxiv 10. Chapter 2: Recent Progress in Single-Cell Sequencing - p. 19 11. Chapter 3: Cellular Heterogeneity and Single-Cell Omics - p. 34 12. Chapter 4: Single-Cell Omics: Cellular Functions - p. 44 13. Chapter 5: Single-Cell Omics: Deciphering Tumor Clonal Architecture - p. 59 14. Section II: Omics Technologies in Single-Cell - p. 97 15. Chapter 6: An Overview of Single-Cell Isolation Techniques - p. 97 16. Chapter 7: Microfluidic Techniques for Single-Cell Culture - p. 135 17. Chapter 8: Single-Cell Omics in Noninvasive Diagnosis and Testing—Surface-Enhanced Raman Spectroscopy-Based Approach - p. 151 18. Chapter 9: Single-Cell Genomics: Technology and Applications - p. 177 19. Chapter 10: Single-Cell Metagenomics - p. 197 20. Chapter 11: Single-Cell Epigenomics: Technology and Applications - p. 213 21. Chapter 12: Single-Cell Transcriptomics: Technology and Applications - p. 229 22. Chapter 13: Single-Cell Transcriptomics and Proteomics of Skeletal Muscle: Technology and Applications - p. 251 23. Chapter 14: Single-Cell Proteomics: Technology and Applications - p. 281 24. Chapter 15: Single-Cell Metabolomics: Technology and Applications - p. 318 25. Chapter 16: Single-Cell Phenomics in Budding Yeast: Technologies and Applications - p. 353 26. Chapter 17: Robotics in Single-Cell Omics - p. 379 27. Chapter 18: Single-Cell Editing: The CRISPR/Cas9 and Applications - p. 395 28. Section III: Data Analysis in Single-Cell Omics - p. 415 29. Chapter 19: Data Analysis in Single-Cell RNA-Seq - p. 415 30. Chapter 20: Systems-Level Understanding of Single-Cell Omics - p. 432 31. Index - p. 457
Single-Cell Omics: Volume 1: Technological Advances and Applications provides the latest technological developments and applications of single-cell technologies in the field of biomedicine. In the current era of precision medicine, the single-cell omics technology is highly promising due to its potential in diagnosis, prognosis and therapeutics. Sections in the book cover single-cell omics research and applications, diverse technologies applied in the topic, such as pangenomics, metabolomics, and multi-omics of single cells, data analysis, and several applications of single-cell omics within the biomedical field, for example in cancer, metabolic and neuro diseases, immunology, pharmacogenomics, personalized medicine and reproductive health.
This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and members of the biomedical field who are interested in understanding more about single-cell omics and its potential for research and diagnosis.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xix 6. About the Editors - p. xxi 7. Preface - p. xxiii 8. Section I: Overview of Single-Cell Omics - p. xxiv 9. Chapter 1: Single-Cell Omics: An Overview - p. xxiv 10. Chapter 2: Recent Progress in Single-Cell Sequencing - p. 19 11. Chapter 3: Cellular Heterogeneity and Single-Cell Omics - p. 34 12. Chapter 4: Single-Cell Omics: Cellular Functions - p. 44 13. Chapter 5: Single-Cell Omics: Deciphering Tumor Clonal Architecture - p. 59 14. Section II: Omics Technologies in Single-Cell - p. 97 15. Chapter 6: An Overview of Single-Cell Isolation Techniques - p. 97 16. Chapter 7: Microfluidic Techniques for Single-Cell Culture - p. 135 17. Chapter 8: Single-Cell Omics in Noninvasive Diagnosis and Testing—Surface-Enhanced Raman Spectroscopy-Based Approach - p. 151 18. Chapter 9: Single-Cell Genomics: Technology and Applications - p. 177 19. Chapter 10: Single-Cell Metagenomics - p. 197 20. Chapter 11: Single-Cell Epigenomics: Technology and Applications - p. 213 21. Chapter 12: Single-Cell Transcriptomics: Technology and Applications - p. 229 22. Chapter 13: Single-Cell Transcriptomics and Proteomics of Skeletal Muscle: Technology and Applications - p. 251 23. Chapter 14: Single-Cell Proteomics: Technology and Applications - p. 281 24. Chapter 15: Single-Cell Metabolomics: Technology and Applications - p. 318 25. Chapter 16: Single-Cell Phenomics in Budding Yeast: Technologies and Applications - p. 353 26. Chapter 17: Robotics in Single-Cell Omics - p. 379 27. Chapter 18: Single-Cell Editing: The CRISPR/Cas9 and Applications - p. 395 28. Section III: Data Analysis in Single-Cell Omics - p. 415 29. Chapter 19: Data Analysis in Single-Cell RNA-Seq - p. 415 30. Chapter 20: Systems-Level Understanding of Single-Cell Omics - p. 432 31. Index - p. 457
