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Since the late 90’s, a renewed interest in the neurobiology of sleep has provided new advancements in the understanding of basic sleep science and the clinical aspects of sleep disorders, with particular interest given to the role of genetics.

From laboratory techniques and therapies, groundbreaking research in sleep-wakefulness, new models of rapid eye movement (REM) sleep mechanisms, to bright light therapy for circadian rhythm sleep disorders, this handbook will provide clinicians and researchers with a state-of-the-art reference that summarizes the clinical features and management of the many neurological manifestations of sleep disorders.

Practitioners will find invaluable research, information, and laboratory techniques on such topics as sleep-wake-dependent genes, the role of sleep duration in mortality and morbidity, and advancements in the understanding of the neurobiology of sleep disorders, including narcolepsy-cataplexy, restless legs syndrome, REM behavior disorders, fatal familiar insomnia, sleep apnea and heart failure, and nocturnal paroxysmal dystonia, amongst others. In addition, significant advancements in therapies and drug protocols are presented.



* Clinical data on groundbreaking advancements in the understanding of basic sleep science
* Invaluable information on new therapies and drug protocols for sleep disorders
* A state-of-the-art reference that includes the role of genetics in sleep medicine

1. Cover 2. Table of Contents 3. Series editors 4. Copyright 5. Handbook of Clinical Neurology 3rd Series 6. Foreword 7. Preface 8. Acknowledgments 9. List of contributors 10. Chapter 1: History of sleep medicine 11. Chapter 2: Normal sleep-recording and scoring techniques 12. Chapter 3: Assessment of daytime sleepiness 13. Chapter 4: Actigraphic monitoring of sleep and circadian rhythms 14. Chapter 5: Video recordings and video polysomnography 15. Chapter 6: Functional neuroimaging in sleep, sleep deprivation, and sleep disorders 16. Chapter 7: The phylogeny of sleep 17. Chapter 8: Ontogeny of EEG sleep from neonatal through infancy periods 18. Chapter 9: Neurobiology of waking and sleeping 19. Chapter 10: Neurobiology of REM sleep 20. Chapter 11: Neurochemistry of sleep 21. Chapter 12: Molecular neurobiology of sleep 22. Chapter 13: Manifestations and functional implications of sleep homeostasis 23. Chapter 14: Thermoregulation in wakefulness and sleep in humans 24. Chapter 15: Cytokines in immune function and sleep regulation 25. Chapter 16: Endocrine and metabolic changes during sleep 26. Chapter 17: Sleep, memory, and molecular neurobiology 27. Chapter 18: Epidemiology of sleep disorders 28. Chapter 19: Cardiovascular and cerebrovascular physiology in sleep 29. Chapter 20: Cardiovascular diseases and sleep apnea 30. Chapter 21: Alterations in gastrointestinal functioning during sleep 31. Chapter 22: Sleep and genitourinary systems: physiology and disorders 32. Chapter 23: Sleep enuresis 33. Chapter 24: Respiratory physiology in sleep and wakefulness 34. Chapter 25: Obstructive sleep apnea: diagnosis, risk factors, and pathophysiology 35. Chapter 26: Upper-airway resistance syndrome 36. Chapter 27: Central sleep apnea 37. Chapter 28: Positive-pressure treatment of obstructive sleep apnea syndrome 38. Chapter 29: Medical and surgical treatment of obstructive sleep apnea syndrome, including dental appliances 39. Chapter 30: Noninvasive positive ventilation in the treatment of sleep-related breathing disorders 40. Chapter 31: Sleep and pulmonary diseases 41. Chapter 32: Sleep-associated respiratory disorders and their psychobehavioral consequences in children 42. Chapter 33: Sudden death in infants during sleep 43. Chapter 34: Neurobiology and the neurological basis of dreaming 44. Chapter 35: Abnormal dreams and nightmare disorders 45. Chapter 36: Sleep and psychiatric diseases 46. Chapter 37: Sleep-related eating disorder 47. Chapter 38: Alcohol, toxins, and medications as a cause of sleep dysfunction 48. Chapter 39: Sleep, pain, fibromyalgia, and chronic fatigue syndrome 49. Chapter 40: Women and sleep 50. Chapter 41: Normal and abnormal sleep in the elderly 51. Subject Index

Descripcion
Descripción

Since the late 90’s, a renewed interest in the neurobiology of sleep has provided new advancements in the understanding of basic sleep science and the clinical aspects of sleep disorders, with particular interest given to the role of genetics.

From laboratory techniques and therapies, groundbreaking research in sleep-wakefulness, new models of rapid eye movement (REM) sleep mechanisms, to bright light therapy for circadian rhythm sleep disorders, this handbook will provide clinicians and researchers with a state-of-the-art reference that summarizes the clinical features and management of the many neurological manifestations of sleep disorders.

Practitioners will find invaluable research, information, and laboratory techniques on such topics as sleep-wake-dependent genes, the role of sleep duration in mortality and morbidity, and advancements in the understanding of the neurobiology of sleep disorders, including narcolepsy-cataplexy, restless legs syndrome, REM behavior disorders, fatal familiar insomnia, sleep apnea and heart failure, and nocturnal paroxysmal dystonia, amongst others. In addition, significant advancements in therapies and drug protocols are presented.



* Clinical data on groundbreaking advancements in the understanding of basic sleep science
* Invaluable information on new therapies and drug protocols for sleep disorders
* A state-of-the-art reference that includes the role of genetics in sleep medicine

1. Cover 2. Table of Contents 3. Series editors 4. Copyright 5. Handbook of Clinical Neurology 3rd Series 6. Foreword 7. Preface 8. Acknowledgments 9. List of contributors 10. Chapter 1: History of sleep medicine 11. Chapter 2: Normal sleep-recording and scoring techniques 12. Chapter 3: Assessment of daytime sleepiness 13. Chapter 4: Actigraphic monitoring of sleep and circadian rhythms 14. Chapter 5: Video recordings and video polysomnography 15. Chapter 6: Functional neuroimaging in sleep, sleep deprivation, and sleep disorders 16. Chapter 7: The phylogeny of sleep 17. Chapter 8: Ontogeny of EEG sleep from neonatal through infancy periods 18. Chapter 9: Neurobiology of waking and sleeping 19. Chapter 10: Neurobiology of REM sleep 20. Chapter 11: Neurochemistry of sleep 21. Chapter 12: Molecular neurobiology of sleep 22. Chapter 13: Manifestations and functional implications of sleep homeostasis 23. Chapter 14: Thermoregulation in wakefulness and sleep in humans 24. Chapter 15: Cytokines in immune function and sleep regulation 25. Chapter 16: Endocrine and metabolic changes during sleep 26. Chapter 17: Sleep, memory, and molecular neurobiology 27. Chapter 18: Epidemiology of sleep disorders 28. Chapter 19: Cardiovascular and cerebrovascular physiology in sleep 29. Chapter 20: Cardiovascular diseases and sleep apnea 30. Chapter 21: Alterations in gastrointestinal functioning during sleep 31. Chapter 22: Sleep and genitourinary systems: physiology and disorders 32. Chapter 23: Sleep enuresis 33. Chapter 24: Respiratory physiology in sleep and wakefulness 34. Chapter 25: Obstructive sleep apnea: diagnosis, risk factors, and pathophysiology 35. Chapter 26: Upper-airway resistance syndrome 36. Chapter 27: Central sleep apnea 37. Chapter 28: Positive-pressure treatment of obstructive sleep apnea syndrome 38. Chapter 29: Medical and surgical treatment of obstructive sleep apnea syndrome, including dental appliances 39. Chapter 30: Noninvasive positive ventilation in the treatment of sleep-related breathing disorders 40. Chapter 31: Sleep and pulmonary diseases 41. Chapter 32: Sleep-associated respiratory disorders and their psychobehavioral consequences in children 42. Chapter 33: Sudden death in infants during sleep 43. Chapter 34: Neurobiology and the neurological basis of dreaming 44. Chapter 35: Abnormal dreams and nightmare disorders 45. Chapter 36: Sleep and psychiatric diseases 46. Chapter 37: Sleep-related eating disorder 47. Chapter 38: Alcohol, toxins, and medications as a cause of sleep dysfunction 48. Chapter 39: Sleep, pain, fibromyalgia, and chronic fatigue syndrome 49. Chapter 40: Women and sleep 50. Chapter 41: Normal and abnormal sleep in the elderly 51. Subject Index

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