Smell and Taste, Volume 164 focuses on recent clinical research regarding two of our primary chemical senses, smell and taste. This volume is the most comprehensive neurology book on disorders of smell and taste function. Its major sections include epidemiology, anatomy and physiology, and clinical assessment, including neuroimaging, clinical conditions affecting smell and taste function (e.g., autoimmune disorders, head trauma, diseases of the nose and mouth, etc.). The widespread use of olfactory testing in clinical trials searching for biomarkers of neurodegenerative diseases is reviewed, along with evidence that smell dysfunction can be an early marker in neurodegenerative diseases and autoimmune disorders.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Available titles - p. v 6. Foreword - p. vii 7. Preface - p. ix 8. Contributors - p. xi 9. Section I: Basic principles - p. xi 10. A. Fundamentals - p. xi 11. Chapter 1: Epidemiology of smell and taste dysfunction - p. xi 12. B. Morphophysiology of the olfactory and nasal trigeminal sensory systems - p. 13 13. Chapter 2: Anatomy of the olfactory system - p. 13 14. Chapter 3: Development of the human olfactory system - p. 28 15. Chapter 4: Anatomy of the olfactory mucosa - p. 45 16. Chapter 5: Olfactory receptor function - p. 65 17. Chapter 6: Central olfactory structures - p. 78 18. Chapter 7: Taste and smell processing in the brain - p. 96 19. Chapter 8: The intranasal trigeminal system - p. 118 20. Chapter 9: Cranial nerve 13 - p. 134 21. C. Morphophysiology of the gustatory and oral trigeminal systems - p. 144 22. Chapter 10: Anatomy and development of the human taste system - p. 144 23. Chapter 11: Taste receptor function - p. 171 24. Chapter 12: Central taste anatomy and physiology - p. 185 25. Chapter 13: The orotrigeminal system - p. 204 26. Section II: Clinical aspects - p. 216 27. A. Clinical assessment - p. 216 28. Chapter 14: Health histories and medical evaluations of patients with complaints of chemosensory dysfunction - p. 216 29. Chapter 15: Psychophysical testing of smell and taste function - p. 227 30. Chapter 16: Electrophysiologic assessment of olfactory and gustatory function - p. 246 31. Chapter 17: Neuroimaging of smell and taste - p. 262 32. B. Diseases and disorders - p. 282 33. Chapter 18: Diseases of the nasal cavity - p. 282 34. Chapter 19: Neurolocalization of taste disorders - p. 302 35. Chapter 20: Chemosensory dysfunction in neurodegenerative diseases - p. 323 36. Chapter 21: Systemic diseases and disorders - p. 360 37. Chapter 22: Toxic exposures and the senses of taste and smell - p. 387 38. Chapter 23: The influence of head injury on olfactory and gustatory function - p. 408 39. Chapter 24: Animal models of olfactory dysfunction in neurodegenerative diseases - p. 429 40. C. Treatment and management of chemosensory disorders - p. 452 41. Chapter 25: Treatments for smell and taste disorders: A critical review - p. 452 42. Index - p. 481
Smell and Taste, Volume 164 focuses on recent clinical research regarding two of our primary chemical senses, smell and taste. This volume is the most comprehensive neurology book on disorders of smell and taste function. Its major sections include epidemiology, anatomy and physiology, and clinical assessment, including neuroimaging, clinical conditions affecting smell and taste function (e.g., autoimmune disorders, head trauma, diseases of the nose and mouth, etc.). The widespread use of olfactory testing in clinical trials searching for biomarkers of neurodegenerative diseases is reviewed, along with evidence that smell dysfunction can be an early marker in neurodegenerative diseases and autoimmune disorders.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Available titles - p. v 6. Foreword - p. vii 7. Preface - p. ix 8. Contributors - p. xi 9. Section I: Basic principles - p. xi 10. A. Fundamentals - p. xi 11. Chapter 1: Epidemiology of smell and taste dysfunction - p. xi 12. B. Morphophysiology of the olfactory and nasal trigeminal sensory systems - p. 13 13. Chapter 2: Anatomy of the olfactory system - p. 13 14. Chapter 3: Development of the human olfactory system - p. 28 15. Chapter 4: Anatomy of the olfactory mucosa - p. 45 16. Chapter 5: Olfactory receptor function - p. 65 17. Chapter 6: Central olfactory structures - p. 78 18. Chapter 7: Taste and smell processing in the brain - p. 96 19. Chapter 8: The intranasal trigeminal system - p. 118 20. Chapter 9: Cranial nerve 13 - p. 134 21. C. Morphophysiology of the gustatory and oral trigeminal systems - p. 144 22. Chapter 10: Anatomy and development of the human taste system - p. 144 23. Chapter 11: Taste receptor function - p. 171 24. Chapter 12: Central taste anatomy and physiology - p. 185 25. Chapter 13: The orotrigeminal system - p. 204 26. Section II: Clinical aspects - p. 216 27. A. Clinical assessment - p. 216 28. Chapter 14: Health histories and medical evaluations of patients with complaints of chemosensory dysfunction - p. 216 29. Chapter 15: Psychophysical testing of smell and taste function - p. 227 30. Chapter 16: Electrophysiologic assessment of olfactory and gustatory function - p. 246 31. Chapter 17: Neuroimaging of smell and taste - p. 262 32. B. Diseases and disorders - p. 282 33. Chapter 18: Diseases of the nasal cavity - p. 282 34. Chapter 19: Neurolocalization of taste disorders - p. 302 35. Chapter 20: Chemosensory dysfunction in neurodegenerative diseases - p. 323 36. Chapter 21: Systemic diseases and disorders - p. 360 37. Chapter 22: Toxic exposures and the senses of taste and smell - p. 387 38. Chapter 23: The influence of head injury on olfactory and gustatory function - p. 408 39. Chapter 24: Animal models of olfactory dysfunction in neurodegenerative diseases - p. 429 40. C. Treatment and management of chemosensory disorders - p. 452 41. Chapter 25: Treatments for smell and taste disorders: A critical review - p. 452 42. Index - p. 481
