Studies in Natural Products Chemistry, Volume 63, covers the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques that have made it possible to rapidly isolate and determine the structures and biological activity of natural products. The book highlights these new and exciting opportunities in the field of new drug development to the pharmaceutical industry. As natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects, this book is an ideal resource on the material presented.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xiii 6. Preface - p. xvii 7. Chapter 1: Recent advances in the licorice root constituent dibenzoylmethane as a potential therapeutic option for cancer - p. xviii 8. Chapter 2: Polyphenols for skin cancer: Chemical properties, structure-related mechanisms of action and new delivery systems - p. 19 9. Chapter 3: The Leucetta alkaloids: Synthetic aspects - p. 42 10. Chapter 4: Metal-catalyzed, bidentate directing group-assisted C−H functionalization: Application to the synthesis of complex natural products - p. 79 11. Chapter 5: Antioxidant, anti-inflammatory and anticancer potential of natural bioactive compounds from seaweeds - p. 112 12. Chapter 6: Comparison of the ginsenoside composition of Asian ginseng (Panax ginseng) and American ginseng (Panax quinquefolius L.) and their transformation pathways - p. 160 13. Chapter 7: Use of natural products in the prevention and management of type 2 diabetes - p. 195 14. Chapter 8: In vitro fucoxanthin production by the Phaeodactylum tricornutum diatom - p. 210 15. Chapter 9: Neuroprotective potential of phytochemicals via in silico molecular docking techniques - p. 242 16. Chapter 10: Isolation and structure elucidation of bioactive polyphenols - p. 266 17. Chapter 11: Curcumin and molecular targets in eye diseases - p. 337 18. Chapter 12: Phytochemistry and biological activities of algerian Centaurea and related genera - p. 356 19. Chapter 13: Phytoconstituent plumbagin: Chemical, biotechnological and pharmaceutical aspects - p. 414 20. Chapter 14: Advances in the synthesis of furo[2,3-b]furanone-containing natural products - p. 460 21. Chapter 15: Advances in dammarane-type triterpenoid saponins from Bacopa monnieri: Structure, bioactivity, biotechnology and neuroprotection - p. 487 22. Index - p. 535
Studies in Natural Products Chemistry, Volume 63, covers the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques that have made it possible to rapidly isolate and determine the structures and biological activity of natural products. The book highlights these new and exciting opportunities in the field of new drug development to the pharmaceutical industry. As natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects, this book is an ideal resource on the material presented.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Contributors - p. xiii 6. Preface - p. xvii 7. Chapter 1: Recent advances in the licorice root constituent dibenzoylmethane as a potential therapeutic option for cancer - p. xviii 8. Chapter 2: Polyphenols for skin cancer: Chemical properties, structure-related mechanisms of action and new delivery systems - p. 19 9. Chapter 3: The Leucetta alkaloids: Synthetic aspects - p. 42 10. Chapter 4: Metal-catalyzed, bidentate directing group-assisted C−H functionalization: Application to the synthesis of complex natural products - p. 79 11. Chapter 5: Antioxidant, anti-inflammatory and anticancer potential of natural bioactive compounds from seaweeds - p. 112 12. Chapter 6: Comparison of the ginsenoside composition of Asian ginseng (Panax ginseng) and American ginseng (Panax quinquefolius L.) and their transformation pathways - p. 160 13. Chapter 7: Use of natural products in the prevention and management of type 2 diabetes - p. 195 14. Chapter 8: In vitro fucoxanthin production by the Phaeodactylum tricornutum diatom - p. 210 15. Chapter 9: Neuroprotective potential of phytochemicals via in silico molecular docking techniques - p. 242 16. Chapter 10: Isolation and structure elucidation of bioactive polyphenols - p. 266 17. Chapter 11: Curcumin and molecular targets in eye diseases - p. 337 18. Chapter 12: Phytochemistry and biological activities of algerian Centaurea and related genera - p. 356 19. Chapter 13: Phytoconstituent plumbagin: Chemical, biotechnological and pharmaceutical aspects - p. 414 20. Chapter 14: Advances in the synthesis of furo[2,3-b]furanone-containing natural products - p. 460 21. Chapter 15: Advances in dammarane-type triterpenoid saponins from Bacopa monnieri: Structure, bioactivity, biotechnology and neuroprotection - p. 487 22. Index - p. 535