Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures, which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up to the pharmaceutical industry exciting opportunities in the field of new drug development. The series covers all of the above as well as the synthesis, testing and recording of the medicinal properties of natural products.
1. Cover image 2. Title page 3. Table of Contents 4. Copyright 5. Contributors 6. Preface 7. Chapter 1. Bioprospecting in the Berkeley Pit: The Use of Signal Transduction Enzyme Inhibition Assays to Isolate Bioactive Secondary Metabolites from the Extremophilic Fungi of an Acid Mine Waste Lake 8. Chapter 2. Natural and Synthetic Chalcones: Tools for the Study of Targets of Action—Insulin Secretagogue or Insulin Mimetic? 9. Chapter 3. Natural Matrix Metalloproteinase Inhibitors: Leads from Herbal Resources 10. Chapter 4. Materials Science and Engineering of Mucin: A New Aspect of Mucin Chemistry 11. Chapter 5. Recent Advances in the Synthetic Studies of Pestalotiopsin A and Related Caryophyllene-Type Sesquiterpenoids 12. Chapter 6. Emerging Targets in the Bioactivity of Ellipticines and Derivatives 13. Chapter 7. Bioactive Natural Products from Enantiomeric Carvones 14. Chapter 8. Plant Polyphenols: Recent Advances in Epidemiological Research and Other Studies on Cancer Prevention 15. Chapter 9. Bioprospection of Potential Trypanocidal Drugs: A Scientific Literature Survey over the Period 2000—2010 16. Chapter 10. Accumulation of Potential Pharmaceutically Relevant Lichen Metabolites in Lichens and Cultured Lichen Symbionts 17. Chapter 11. Plant-Derived Natural Products for the Treatment of Leishmaniasis 18. Chapter 12. Development and Discovery Avenues in Bioactive Natural Products for Glycemic Novel Therapeutics 19. Index
Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures, which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up to the pharmaceutical industry exciting opportunities in the field of new drug development. The series covers all of the above as well as the synthesis, testing and recording of the medicinal properties of natural products.
1. Cover image 2. Title page 3. Table of Contents 4. Copyright 5. Contributors 6. Preface 7. Chapter 1. Bioprospecting in the Berkeley Pit: The Use of Signal Transduction Enzyme Inhibition Assays to Isolate Bioactive Secondary Metabolites from the Extremophilic Fungi of an Acid Mine Waste Lake 8. Chapter 2. Natural and Synthetic Chalcones: Tools for the Study of Targets of Action—Insulin Secretagogue or Insulin Mimetic? 9. Chapter 3. Natural Matrix Metalloproteinase Inhibitors: Leads from Herbal Resources 10. Chapter 4. Materials Science and Engineering of Mucin: A New Aspect of Mucin Chemistry 11. Chapter 5. Recent Advances in the Synthetic Studies of Pestalotiopsin A and Related Caryophyllene-Type Sesquiterpenoids 12. Chapter 6. Emerging Targets in the Bioactivity of Ellipticines and Derivatives 13. Chapter 7. Bioactive Natural Products from Enantiomeric Carvones 14. Chapter 8. Plant Polyphenols: Recent Advances in Epidemiological Research and Other Studies on Cancer Prevention 15. Chapter 9. Bioprospection of Potential Trypanocidal Drugs: A Scientific Literature Survey over the Period 2000—2010 16. Chapter 10. Accumulation of Potential Pharmaceutically Relevant Lichen Metabolites in Lichens and Cultured Lichen Symbionts 17. Chapter 11. Plant-Derived Natural Products for the Treatment of Leishmaniasis 18. Chapter 12. Development and Discovery Avenues in Bioactive Natural Products for Glycemic Novel Therapeutics 19. Index