Supercritical fluid chromatography (SFC) is a rapidly developing laboratory technique for the separation and identification of compounds in mixtures. Significant improvements in instrumentation have rekindled interest in SFC in recent years and enhanced its standing in the scientific community. Many scientists are familiar with column liquid chromatography and its strengths and weaknesses, but the possibilities brought to the table by SFC are less well-known and are underappreciated.
Supercritical Fluid Chromatography is a thorough and encompassing reference that defines the concept of contemporary practice in SFC and how it should be implemented in laboratory science. Given the changes that have taken place in SFC, this book presents contemporary aspects and applications of the technique and introduces SFC as a natural solution in the larger field of separation science. The focus on state-of-the-art instrumental SFC distinguishes this work as the go-to reference work for those interested in implementing the technique at an advanced level.
1. Cover image - p. Cover 2. Title page - p. iii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. List of Contributors - p. xi 6. Handbooks in Separation Science Series - p. xiii 7. Chapter 1. Milestones in Supercritical Fluid Chromatography: A Historical View of the Modernization and Development of Supercritical Fluid Chromatography - p. 1 8. Chapter 2. Theory of Supercritical Fluid Chromatography - p. 23 9. Chapter 3. Practical Approaches to Column Selection for Supercritical Fluid Chromatography - p. 57 10. Chapter 4. Column Characterization - p. 103 11. Chapter 5. Method Development in Supercritical Fluid Chromatography - p. 127 12. Chapter 6. Application of Multiple Column Supercritical Fluid Chromatography - p. 153 13. Chapter 7. Evolution of Instrumentation for Analytical Scale Supercritical Fluid Chromatography - p. 173 14. Chapter 8. Hyphenated Detectors: Mass Spectrometry - p. 213 15. Chapter 9. Theories for Preparative SFC - p. 245 16. Chapter 10. Practical Aspects and Applications of Preparative Supercritical Fluid Chromatography - p. 275 17. Chapter 11. Validation of Supercritical Fluid Chromatography Methods - p. 317 18. Chapter 12. Separation of Stereoisomers - p. 345 19. Chapter 13. Supercritical Fluid Chromatography of Petroleum Products - p. 381 20. Chapter 14. Separation of Lipids - p. 419 21. Chapter 15. Separation of Natural Products - p. 439 22. Chapter 16. Pharmaceutical Applications - p. 461 23. Chapter 17. Applications to Food Analysis - p. 495 24. Chapter 18. Physicochemical Property Measurements Using SFC Instrumentation - p. 515 25. Index - p. 541
Supercritical fluid chromatography (SFC) is a rapidly developing laboratory technique for the separation and identification of compounds in mixtures. Significant improvements in instrumentation have rekindled interest in SFC in recent years and enhanced its standing in the scientific community. Many scientists are familiar with column liquid chromatography and its strengths and weaknesses, but the possibilities brought to the table by SFC are less well-known and are underappreciated.
Supercritical Fluid Chromatography is a thorough and encompassing reference that defines the concept of contemporary practice in SFC and how it should be implemented in laboratory science. Given the changes that have taken place in SFC, this book presents contemporary aspects and applications of the technique and introduces SFC as a natural solution in the larger field of separation science. The focus on state-of-the-art instrumental SFC distinguishes this work as the go-to reference work for those interested in implementing the technique at an advanced level.
1. Cover image - p. Cover 2. Title page - p. iii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. List of Contributors - p. xi 6. Handbooks in Separation Science Series - p. xiii 7. Chapter 1. Milestones in Supercritical Fluid Chromatography: A Historical View of the Modernization and Development of Supercritical Fluid Chromatography - p. 1 8. Chapter 2. Theory of Supercritical Fluid Chromatography - p. 23 9. Chapter 3. Practical Approaches to Column Selection for Supercritical Fluid Chromatography - p. 57 10. Chapter 4. Column Characterization - p. 103 11. Chapter 5. Method Development in Supercritical Fluid Chromatography - p. 127 12. Chapter 6. Application of Multiple Column Supercritical Fluid Chromatography - p. 153 13. Chapter 7. Evolution of Instrumentation for Analytical Scale Supercritical Fluid Chromatography - p. 173 14. Chapter 8. Hyphenated Detectors: Mass Spectrometry - p. 213 15. Chapter 9. Theories for Preparative SFC - p. 245 16. Chapter 10. Practical Aspects and Applications of Preparative Supercritical Fluid Chromatography - p. 275 17. Chapter 11. Validation of Supercritical Fluid Chromatography Methods - p. 317 18. Chapter 12. Separation of Stereoisomers - p. 345 19. Chapter 13. Supercritical Fluid Chromatography of Petroleum Products - p. 381 20. Chapter 14. Separation of Lipids - p. 419 21. Chapter 15. Separation of Natural Products - p. 439 22. Chapter 16. Pharmaceutical Applications - p. 461 23. Chapter 17. Applications to Food Analysis - p. 495 24. Chapter 18. Physicochemical Property Measurements Using SFC Instrumentation - p. 515 25. Index - p. 541
