Synthesis of Six- and Seven-Membered Heterocycles: The Role of DMF and its Synthesis compares different synthetic approaches using DMF, including the advantages and disadvantages of those reactions, green methods, and the sustainability of reported synthetic methodologies, especially the microwave methods. The book presents several methodologies for the synthesis of six- and seven-membered heterocyclic compounds using dimethylformamide. Users will find the most up-to-date information in this fast-moving field which can be particularly challenging. With DMF drawing the attention of synthetic organic chemists, this book will help readers understand further developments in the uses of dimethylformamide beyond just its use as a polar solvent.
As it can be expected that the use of dimethylformamide as a precursor will continue to grow in organic synthesis with new applications in sustainable and green chemistry, this book provides an ideal primer on the topics covered.
1. Synthesis of 6- and 7-Membered Heterocycles - p. i 2. Cover - p. i 3. Title Page - p. iii 4. Copyright Page - p. iv 5. Contents - p. v 6. About the author - p. ix 7. Preface - p. xi 8. 1 Synthesis of pyridines - p. 1 9. 2 Synthesis of fused pyridines and piperidines - p. 27 10. 3 Synthesis of quinolines - p. 57 11. 4 Synthesis of isoquinolines - p. 91 12. 5 Synthesis of pyrimidines - p. 117 13. 6 Synthesis of pyridazines, pyrazines, quinazolines, quinoxalines, triazines, and tetrazines - p. 155 14. 7 Synthesis of pyrans and benzopyrans - p. 199 15. 8 Synthesis of fused benzopyrans - p. 229 16. 9 Synthesis of oxazines, benzoxazines, thiopyrans, and thiazines - p. 259 17. 10 Synthesis of azepines, diazepines, triazepines, oxepines, oxazepines, and thiapines - p. 281 18. Index - p. 325
Synthesis of Six- and Seven-Membered Heterocycles: The Role of DMF and its Synthesis compares different synthetic approaches using DMF, including the advantages and disadvantages of those reactions, green methods, and the sustainability of reported synthetic methodologies, especially the microwave methods. The book presents several methodologies for the synthesis of six- and seven-membered heterocyclic compounds using dimethylformamide. Users will find the most up-to-date information in this fast-moving field which can be particularly challenging. With DMF drawing the attention of synthetic organic chemists, this book will help readers understand further developments in the uses of dimethylformamide beyond just its use as a polar solvent.
As it can be expected that the use of dimethylformamide as a precursor will continue to grow in organic synthesis with new applications in sustainable and green chemistry, this book provides an ideal primer on the topics covered.
1. Synthesis of 6- and 7-Membered Heterocycles - p. i 2. Cover - p. i 3. Title Page - p. iii 4. Copyright Page - p. iv 5. Contents - p. v 6. About the author - p. ix 7. Preface - p. xi 8. 1 Synthesis of pyridines - p. 1 9. 2 Synthesis of fused pyridines and piperidines - p. 27 10. 3 Synthesis of quinolines - p. 57 11. 4 Synthesis of isoquinolines - p. 91 12. 5 Synthesis of pyrimidines - p. 117 13. 6 Synthesis of pyridazines, pyrazines, quinazolines, quinoxalines, triazines, and tetrazines - p. 155 14. 7 Synthesis of pyrans and benzopyrans - p. 199 15. 8 Synthesis of fused benzopyrans - p. 229 16. 9 Synthesis of oxazines, benzoxazines, thiopyrans, and thiazines - p. 259 17. 10 Synthesis of azepines, diazepines, triazepines, oxepines, oxazepines, and thiapines - p. 281 18. Index - p. 325
