Synthesis of Epoxides explores different techniques for making epoxides, both old and new, and delves into the growing field of heterocyclic chemistry. The book presents a variety of methods that will help readers figure out which one best suits their specific needs. Diazo compounds are important synthetic intermediates in organic synthesis, but because of their unpredictable, explosive nature and toxicity their unique reactivity has not been fully exploited and their use at large scale has been avoided. Readers, including students in chemistry, will learn about different methods and important information, allowing them to evaluate which method is most suitable in particular cases.
The synthetic usefulness of diazo compounds cannot be overlooked despite their danger. Because of their ylide and 1,3-dipole nature, the diazo compounds have a unique reactivity. The diazo compounds can be utilized for various different conversions including S-ylide-assisted epoxidation, cyclopropanation, or aziridination reactions. This book describes the new and classic methods for the synthesis of epoxides and covers an important and rapidly growing branch of heterocyclic chemistry.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. About the author - p. ix 7. Preface - p. xi 8. Abbreviations - p. xiii 9. 1. Epoxide synthesis - p. 1 10. 2. Epoxide synthesis from alcohols - p. 27 11. 3. Epoxide synthesis from diazo compounds - p. 47 12. 4. Epoxide synthesis from diols - p. 83 13. 5. Epoxide synthesis from diols using sodium reagents - p. 109 14. 6. Epoxide synthesis from haloalcohols - p. 131 15. 7. Epoxide synthesis from carbonyl compounds-I - p. 181 16. 8. Epoxide synthesis from carbonyl compounds-II - p. 201 17. 9. Epoxide synthesis from carbonyl compounds using sulfur ylides-I - p. 229 18. 10. Epoxide synthesis from carbonyl compounds using sulfur ylides-II - p. 257 19. 11. Epoxide synthesis from carbonyl and halo compounds - p. 277 20. 12. Epoxide synthesis from carbonyl and halo compounds using sulfides - p. 309 21. Index - p. 329
Synthesis of Epoxides explores different techniques for making epoxides, both old and new, and delves into the growing field of heterocyclic chemistry. The book presents a variety of methods that will help readers figure out which one best suits their specific needs. Diazo compounds are important synthetic intermediates in organic synthesis, but because of their unpredictable, explosive nature and toxicity their unique reactivity has not been fully exploited and their use at large scale has been avoided. Readers, including students in chemistry, will learn about different methods and important information, allowing them to evaluate which method is most suitable in particular cases.
The synthetic usefulness of diazo compounds cannot be overlooked despite their danger. Because of their ylide and 1,3-dipole nature, the diazo compounds have a unique reactivity. The diazo compounds can be utilized for various different conversions including S-ylide-assisted epoxidation, cyclopropanation, or aziridination reactions. This book describes the new and classic methods for the synthesis of epoxides and covers an important and rapidly growing branch of heterocyclic chemistry.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. About the author - p. ix 7. Preface - p. xi 8. Abbreviations - p. xiii 9. 1. Epoxide synthesis - p. 1 10. 2. Epoxide synthesis from alcohols - p. 27 11. 3. Epoxide synthesis from diazo compounds - p. 47 12. 4. Epoxide synthesis from diols - p. 83 13. 5. Epoxide synthesis from diols using sodium reagents - p. 109 14. 6. Epoxide synthesis from haloalcohols - p. 131 15. 7. Epoxide synthesis from carbonyl compounds-I - p. 181 16. 8. Epoxide synthesis from carbonyl compounds-II - p. 201 17. 9. Epoxide synthesis from carbonyl compounds using sulfur ylides-I - p. 229 18. 10. Epoxide synthesis from carbonyl compounds using sulfur ylides-II - p. 257 19. 11. Epoxide synthesis from carbonyl and halo compounds - p. 277 20. 12. Epoxide synthesis from carbonyl and halo compounds using sulfides - p. 309 21. Index - p. 329
