Synthetic Strategies in Carbohydrate Chemistry covers carbohydrate synthesis and its widespread application in various disciplines including catalysis. Basic and advanced aspects of carbohydrates are covered, starting with a brief introduction and then followed by protection-deprotection strategies in carbohydrate chemistry, glycosidic bond formation methodology, and their impact in oligosaccharide synthesis. Recent synthetic approaches for O-glycosides, N-glycosides, thioglycosides and C-glycosides, Intramolecular Aglycon Delivery (IAD), and carbohydrate modification are discussed, as well as stereoelectronic factors that control the chemical and biochemical behavior of carbohydrates in living cells.
In addition, diverse applications of synthetic carbohydrate chemistry are covered, including sugar-based chiral catalyst in stereoselective synthesis, sugar-based ionic liquids, one-pot tandem reactions in carbohydrates, total synthesis of glycoconjugated natural products, impact of sugar in drug discovery and development, vaccine development, and glycoengineering. This reference is essential reading for researchers working in synthetic carbohydrate chemistry and biochemistry, and will be useful to those working in total synthesis, novel synthetic methodology, catalysis, polymer science, glycobiology, medicinal chemistry, and process development chemistry.
1. 11.1: Introduction - p. 407 2. 11.2: Natural product-based glycomacrocycles - p. 408 3. 11.3: Sugar-based crown ether, azacrown ether, and other crown ether-like macrocycles - p. 446 4. 11.4: Synthesis of macrocycles by C–C bond forming reactions - p. 464 5. 11.5: Synthesis of sugar-embedded macrocycles by reductive amination, macrolactamization, and macrolactonization - p. 473 6. 11.6: Synthesis of macrocycles via click macrocyclizations - p. 482 7. 11.7: Conclusion and future perspective - p. 515 8. Acknowledgement - p. 516 9. References - p. 516 10. Chapter 12 Recent advances in synthesis of diverse glycopeptides and glycohybrids - p. 523 11. Chapter 13 Carbohydrate-based chiral organocatalysts - p. 611 12. Chapter 14 Emerging aspects of domino reactions in carbohydrate Chemistry - p. 679 13. Index - p. 731
Synthetic Strategies in Carbohydrate Chemistry covers carbohydrate synthesis and its widespread application in various disciplines including catalysis. Basic and advanced aspects of carbohydrates are covered, starting with a brief introduction and then followed by protection-deprotection strategies in carbohydrate chemistry, glycosidic bond formation methodology, and their impact in oligosaccharide synthesis. Recent synthetic approaches for O-glycosides, N-glycosides, thioglycosides and C-glycosides, Intramolecular Aglycon Delivery (IAD), and carbohydrate modification are discussed, as well as stereoelectronic factors that control the chemical and biochemical behavior of carbohydrates in living cells.
In addition, diverse applications of synthetic carbohydrate chemistry are covered, including sugar-based chiral catalyst in stereoselective synthesis, sugar-based ionic liquids, one-pot tandem reactions in carbohydrates, total synthesis of glycoconjugated natural products, impact of sugar in drug discovery and development, vaccine development, and glycoengineering. This reference is essential reading for researchers working in synthetic carbohydrate chemistry and biochemistry, and will be useful to those working in total synthesis, novel synthetic methodology, catalysis, polymer science, glycobiology, medicinal chemistry, and process development chemistry.
1. 11.1: Introduction - p. 407 2. 11.2: Natural product-based glycomacrocycles - p. 408 3. 11.3: Sugar-based crown ether, azacrown ether, and other crown ether-like macrocycles - p. 446 4. 11.4: Synthesis of macrocycles by C–C bond forming reactions - p. 464 5. 11.5: Synthesis of sugar-embedded macrocycles by reductive amination, macrolactamization, and macrolactonization - p. 473 6. 11.6: Synthesis of macrocycles via click macrocyclizations - p. 482 7. 11.7: Conclusion and future perspective - p. 515 8. Acknowledgement - p. 516 9. References - p. 516 10. Chapter 12 Recent advances in synthesis of diverse glycopeptides and glycohybrids - p. 523 11. Chapter 13 Carbohydrate-based chiral organocatalysts - p. 611 12. Chapter 14 Emerging aspects of domino reactions in carbohydrate Chemistry - p. 679 13. Index - p. 731
