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In only the last four years, there have been dramatic changes in the understanding of the immunology, genetic/epigenetic associations, and identification of new targets for therapy in Systemic Lupus Erythematosus. The editors have enlisted a superb group of authors to present articles detailing cutting-edge advances in these areas.

1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. Forthcoming Issues - p. 6 6. Foreword - p. 7 7. Preface - p. 8 8. Environmental Influences on Systemic Lupus Erythematosus Expression - p. 9 9. Clinical Perspectives on Lupus Genetics - p. 15 10. Impact of Race and Ethnicity in the Course and Outcome of Systemic Lupus Erythematosus - p. 27 11. The Immunopathology of Cutaneous Lupus Erythematosus - p. 39 12. Pathogenesis and Treatment of Atherosclerosis in Lupus - p. 48 13. Systemic Lupus Erythematosus and Malignancies - p. 61 14. Post-marketing Experiences with Belimumab in the Treatment of SLE Patients - p. 68 15. Recent Clinical Trials in Lupus Nephritis - p. 74 16. The Kidney Biopsy in Lupus Nephritis - p. 83 17. Improving Participation in Clinical Trials of Novel Therapies - p. 91 18. Index - p. 95

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In only the last four years, there have been dramatic changes in the understanding of the immunology, genetic/epigenetic associations, and identification of new targets for therapy in Systemic Lupus Erythematosus. The editors have enlisted a superb group of authors to present articles detailing cutting-edge advances in these areas.

1. Cover image - p. 1 2. Title page - p. 2 3. Table of Contents - p. 3 4. Contributors - p. 4 5. Forthcoming Issues - p. 6 6. Foreword - p. 7 7. Preface - p. 8 8. Environmental Influences on Systemic Lupus Erythematosus Expression - p. 9 9. Clinical Perspectives on Lupus Genetics - p. 15 10. Impact of Race and Ethnicity in the Course and Outcome of Systemic Lupus Erythematosus - p. 27 11. The Immunopathology of Cutaneous Lupus Erythematosus - p. 39 12. Pathogenesis and Treatment of Atherosclerosis in Lupus - p. 48 13. Systemic Lupus Erythematosus and Malignancies - p. 61 14. Post-marketing Experiences with Belimumab in the Treatment of SLE Patients - p. 68 15. Recent Clinical Trials in Lupus Nephritis - p. 74 16. The Kidney Biopsy in Lupus Nephritis - p. 83 17. Improving Participation in Clinical Trials of Novel Therapies - p. 91 18. Index - p. 95

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