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Tailor-Made Polysaccharides in Drug Delivery provides extensive details on all the vital precepts, basics and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industry for understanding and developing high quality products. The book offers a comprehensive resource to understand the potential of the materials in forming new drug delivery methods. It will be useful to pharmaceutical scientists, chemical engineers, and regulatory scientists and students actively involved in pharmaceutical product and process development of tailored-made polysaccharides in drug delivery applications.

The utilization of natural polymeric excipients in numerous healthcare applications demand the replacement of the synthetic polymers with the natural ones due to their biocompatibility, biodegradability, economic extraction and readily availability. The reality behind the rise in importance of these natural materials is that these sources are renewable if grown in a sustainable means and they can tender incessant supply of raw materials. Amongst these natural polymers, polysaccharides are considered as excellent excipients because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of polysaccharides in drug delivery.

  • Provides methodologies for the design, development and selection of tailor-made, natural polysaccharides in drug delivery for particular therapeutic applications
  • Includes illustrations that demonstrate the mechanism of biological interaction of tailor-made polysaccharides
  • Discusses the regulatory aspects and demonstrates the clinical efficacy of tailor-made polysaccharides

1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contributors - p. xi 7. About the editors - p. xii 8. Preface - p. xv 9. Chapter 1. Synthesis of tailor-made polysaccharides: An overview - p. 1 10. Chapter 2. Drug delivery dosage forms made of tailor-made natural polysaccharides - p. 29 11. Chapter 3. Carboxymethylated polysaccharides in drug delivery - p. 63 12. Chapter 4. Thiolated polysaccharides in drug delivery - p. 83 13. Chapter 5. Cross-linked polysaccharides in drug delivery - p. 107 14. Chapter 6. Graft copolymers of polysaccharides: Synthesis techniques and pharmaceutical applications - p. 129 15. Chapter 7. Grafted polysaccharides in drug delivery - p. 157 16. Chapter 8. Polysaccharide-based polyelectrolyte complex systems in drug delivery - p. 181 17. Chapter 9. Polysaccharide-based interpenetrating polymeric network systems in drug delivery - p. 211 18. Chapter 10. Polysaccharide nanoconjugates in drug delivery - p. 248 19. Chapter 11. Functionalized chitosan in drug delivery - p. 257 20. Chapter 12. Modified alginates in drug delivery - p. 314 21. Chapter 13. Uses of tailor-made plant starches in drug delivery - p. 327 22. Chapter 14. Cancer targeting by tailor-made polysaccharides - p. 347 23. Chapter 15. Delivery of genes and growth factors using tailor-made polysaccharides - p. 377 24. Index - p. 391

Descripcion
Descripción

Tailor-Made Polysaccharides in Drug Delivery provides extensive details on all the vital precepts, basics and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industry for understanding and developing high quality products. The book offers a comprehensive resource to understand the potential of the materials in forming new drug delivery methods. It will be useful to pharmaceutical scientists, chemical engineers, and regulatory scientists and students actively involved in pharmaceutical product and process development of tailored-made polysaccharides in drug delivery applications.

The utilization of natural polymeric excipients in numerous healthcare applications demand the replacement of the synthetic polymers with the natural ones due to their biocompatibility, biodegradability, economic extraction and readily availability. The reality behind the rise in importance of these natural materials is that these sources are renewable if grown in a sustainable means and they can tender incessant supply of raw materials. Amongst these natural polymers, polysaccharides are considered as excellent excipients because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of polysaccharides in drug delivery.

  • Provides methodologies for the design, development and selection of tailor-made, natural polysaccharides in drug delivery for particular therapeutic applications
  • Includes illustrations that demonstrate the mechanism of biological interaction of tailor-made polysaccharides
  • Discusses the regulatory aspects and demonstrates the clinical efficacy of tailor-made polysaccharides

1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iii 6. Contributors - p. xi 7. About the editors - p. xii 8. Preface - p. xv 9. Chapter 1. Synthesis of tailor-made polysaccharides: An overview - p. 1 10. Chapter 2. Drug delivery dosage forms made of tailor-made natural polysaccharides - p. 29 11. Chapter 3. Carboxymethylated polysaccharides in drug delivery - p. 63 12. Chapter 4. Thiolated polysaccharides in drug delivery - p. 83 13. Chapter 5. Cross-linked polysaccharides in drug delivery - p. 107 14. Chapter 6. Graft copolymers of polysaccharides: Synthesis techniques and pharmaceutical applications - p. 129 15. Chapter 7. Grafted polysaccharides in drug delivery - p. 157 16. Chapter 8. Polysaccharide-based polyelectrolyte complex systems in drug delivery - p. 181 17. Chapter 9. Polysaccharide-based interpenetrating polymeric network systems in drug delivery - p. 211 18. Chapter 10. Polysaccharide nanoconjugates in drug delivery - p. 248 19. Chapter 11. Functionalized chitosan in drug delivery - p. 257 20. Chapter 12. Modified alginates in drug delivery - p. 314 21. Chapter 13. Uses of tailor-made plant starches in drug delivery - p. 327 22. Chapter 14. Cancer targeting by tailor-made polysaccharides - p. 347 23. Chapter 15. Delivery of genes and growth factors using tailor-made polysaccharides - p. 377 24. Index - p. 391

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