Offering up-to-date, comprehensive coverage of disease progression, diagnosis, management, and prognosis, Textbook of Pediatric Rheumatology is the definitive reference in the field. For physicians caring for children with rheumatic diseases, this revised 8th Edition is an unparalleled resource for the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents. Global leaders in the field provide reliable, evidence-based guidance, highlighted by superb full-color illustrations that facilitate a thorough understanding of the science that underlies rheumatic disease.
Offers expanded coverage of autoinflammatory diseases, plus new chapters on Takayasu Arteritis and Other Vasculitides, Mechanistic Investigation of Pediatric Rheumatic Diseases, Genetics and Pediatric Rheumatic Diseases, and Global Issues in Pediatric Rheumatology.
Reflects the changes in diagnosis, monitoring, and management that recent advances have made possible.
Covers the latest information on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies, helping you choose treatment protocols based on the best scientific evidence available today.
Features exhaustive reviews of the complex symptoms, signs, and lab abnormalities that characterize these clinical disorders.
1. Introduction - p. 377 2. Demographics and Epidemiology - p. 377 3. Etiology and Pathogenesis - p. 377 4. Diagnosis and Classification of Juvenile Systemic Sclerosis - p. 380 5. Clinical Features - p. 383 6. Patient Reported Outcomes - p. 392 7. Systemic Sclerosis Treatment - p. 394 8. Raynaud Phenomenon - p. 396 9. Digital Ulcers - p. 396 10. The Future of Treatment in Pediatric Systemic Sclerosis - p. 400 11. Prognosis - p. 400 12. 28. Localized Scleroderma and Eosinophilic Fasciitis - p. 402 13. 29. Sjögren Syndrome and Immunoglobulin-G4 Disease - p. 417 14. 30. Raynaud Phenomenon and Vasomotor Syndromes - p. 427 15. Section IV. Vasculitis - p. 437.e3 16. 31. Inflammatory Central Nervous System Disorders - p. 439 17. 32. Vasculitis and Its Classification - p. 451 18. 33. Immune Complex Small-Vessel Vasculitis: IgA Vasculitis (Henoch–Schönlein) and Hypersensitivity Vasculitis - p. 456 19. 34. Polyarteritis Nodosa - p. 467 20. 35. Kawasaki Disease - p. 473 21. 36. Antineutrophil Cytoplasmic Antibody Associated Vasculitis - p. 484 22. 37. Takayasu Arteritis and Other Vasculitides - p. 498 23. Takayasu Arteritis - p. 498 24. Cogan Syndrome - p. 506 25. Immune Complex Small-Vessel Vasculitis - p. 507 26. Vasculitis Associated With Systemic Disease - p. 509 27. Vasculitis Associated With Probable Etiology - p. 510 28. Other Vasculitides, Vasculopathies - p. 511 29. Mimics of Vasculitis - p. 515 30. 38. Behçet Disease - p. 518 31. Section V. Immune System Dysfunction: Autoinflammation and Immunodeficiency - p. 523.e2 32. 39. Periodic Fever Syndromes and Other Inherited Autoinflammatory Diseases - p. 525 33. 40. Autoinflammatory Bone Diseases - p. 544 34. 41. Pediatric Sarcoidosis - p. 559 35. 42. Macrophage Activation Syndrome - p. 567 36. 43. Primary Immunodeficiencies and Rheumatic Diseases - p. 575 37. Section VI. Infection Related Rheumatic Disorders - p. 585.e4 38. 44. Infectious Arthritis and Osteomyelitis - p. 587 39. 45. Lyme Disease - p. 602 40. 46. Reactive Arthritis - p. 613 41. Section VII. Rheumatic Manifestations of Non-Rheumatic Disorders - p. 630.e5 42. 47. Skeletal Malignancies and Related Disorders - p. 631 43. 48. The Impact of Rheumatic Diseases and Their Treatment on Bone Strength Development in Childhood - p. 644 44. 49. Skeletal Dysplasias - p. 657 45. 50. Noninflammatory Musculoskeletal Pain - p. 665 46. 51. Musculoskeletal Manifestations of Inflammatory Bowel Disease - p. 684 47. 52. Musculoskeletal Manifestations of Systemic Disease - p. 691 48. 53. Pain Amplification Syndromes - p. 702 49. 54. Primary Disorders of Connective Tissue - p. 714 50. Index - p. 725
Offering up-to-date, comprehensive coverage of disease progression, diagnosis, management, and prognosis, Textbook of Pediatric Rheumatology is the definitive reference in the field. For physicians caring for children with rheumatic diseases, this revised 8th Edition is an unparalleled resource for the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents. Global leaders in the field provide reliable, evidence-based guidance, highlighted by superb full-color illustrations that facilitate a thorough understanding of the science that underlies rheumatic disease.
Offers expanded coverage of autoinflammatory diseases, plus new chapters on Takayasu Arteritis and Other Vasculitides, Mechanistic Investigation of Pediatric Rheumatic Diseases, Genetics and Pediatric Rheumatic Diseases, and Global Issues in Pediatric Rheumatology.
Reflects the changes in diagnosis, monitoring, and management that recent advances have made possible.
Covers the latest information on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies, helping you choose treatment protocols based on the best scientific evidence available today.
Features exhaustive reviews of the complex symptoms, signs, and lab abnormalities that characterize these clinical disorders.
1. Introduction - p. 377 2. Demographics and Epidemiology - p. 377 3. Etiology and Pathogenesis - p. 377 4. Diagnosis and Classification of Juvenile Systemic Sclerosis - p. 380 5. Clinical Features - p. 383 6. Patient Reported Outcomes - p. 392 7. Systemic Sclerosis Treatment - p. 394 8. Raynaud Phenomenon - p. 396 9. Digital Ulcers - p. 396 10. The Future of Treatment in Pediatric Systemic Sclerosis - p. 400 11. Prognosis - p. 400 12. 28. Localized Scleroderma and Eosinophilic Fasciitis - p. 402 13. 29. Sjögren Syndrome and Immunoglobulin-G4 Disease - p. 417 14. 30. Raynaud Phenomenon and Vasomotor Syndromes - p. 427 15. Section IV. Vasculitis - p. 437.e3 16. 31. Inflammatory Central Nervous System Disorders - p. 439 17. 32. Vasculitis and Its Classification - p. 451 18. 33. Immune Complex Small-Vessel Vasculitis: IgA Vasculitis (Henoch–Schönlein) and Hypersensitivity Vasculitis - p. 456 19. 34. Polyarteritis Nodosa - p. 467 20. 35. Kawasaki Disease - p. 473 21. 36. Antineutrophil Cytoplasmic Antibody Associated Vasculitis - p. 484 22. 37. Takayasu Arteritis and Other Vasculitides - p. 498 23. Takayasu Arteritis - p. 498 24. Cogan Syndrome - p. 506 25. Immune Complex Small-Vessel Vasculitis - p. 507 26. Vasculitis Associated With Systemic Disease - p. 509 27. Vasculitis Associated With Probable Etiology - p. 510 28. Other Vasculitides, Vasculopathies - p. 511 29. Mimics of Vasculitis - p. 515 30. 38. Behçet Disease - p. 518 31. Section V. Immune System Dysfunction: Autoinflammation and Immunodeficiency - p. 523.e2 32. 39. Periodic Fever Syndromes and Other Inherited Autoinflammatory Diseases - p. 525 33. 40. Autoinflammatory Bone Diseases - p. 544 34. 41. Pediatric Sarcoidosis - p. 559 35. 42. Macrophage Activation Syndrome - p. 567 36. 43. Primary Immunodeficiencies and Rheumatic Diseases - p. 575 37. Section VI. Infection Related Rheumatic Disorders - p. 585.e4 38. 44. Infectious Arthritis and Osteomyelitis - p. 587 39. 45. Lyme Disease - p. 602 40. 46. Reactive Arthritis - p. 613 41. Section VII. Rheumatic Manifestations of Non-Rheumatic Disorders - p. 630.e5 42. 47. Skeletal Malignancies and Related Disorders - p. 631 43. 48. The Impact of Rheumatic Diseases and Their Treatment on Bone Strength Development in Childhood - p. 644 44. 49. Skeletal Dysplasias - p. 657 45. 50. Noninflammatory Musculoskeletal Pain - p. 665 46. 51. Musculoskeletal Manifestations of Inflammatory Bowel Disease - p. 684 47. 52. Musculoskeletal Manifestations of Systemic Disease - p. 691 48. 53. Pain Amplification Syndromes - p. 702 49. 54. Primary Disorders of Connective Tissue - p. 714 50. Index - p. 725
