Written by physicians and scientists with expertise in this evolving area, Textbook of SARS-CoV-2 and COVID-19 provides a coherent, readable, and clinically relevant review of the biology, epidemiology, pathophysiology, immunology, clinical features, current treatment, and prevention strategies for the SARS-CoV-2 virus. Using both a systemic and topic-based approach, it summarizes and clarifies the extensive literature published on SARS-CoV-2 and COVID-19, includes a comprehensive bibliography, and provides answers to clinical questions at the point of care from multiple specialty perspectives.
1. Cover Image - p. i 2. Title Page - p. iii 3. Copyright - p. iv 4. Dedication - p. v 5. Contributors - p. vi 6. Acknowledgments - p. ix 7. Preface - p. x 8. Table of Contents - p. xiii 9. Part I The Basics: Epidemiology, Biology, Pathogenesis, Immunology, and Natural History - p. 1 10. Chapter 1 Epidemiology of SARS-CoV-2 and COVID-19 - p. 2 11. Chapter 2 SARS-CoV-2: Structure, Pathogenesis, and Diagnosis - p. 24 12. Chapter 3 Immunology of COVID-19 - p. 52 13. Chapter 4 COVID-19: Natural History and Spectrum of Disease - p. 72 14. Part II The Clinical: Manifestations in Systems and Domains of the Body - p. 99 15. Chapter 5 Pulmonary Manifestations of COVID-19 - p. 100 16. Chapter 6 COVID-19 and the Cardiovascular System - p. 137 17. Chapter 7 Neurological Manifestations of COVID-19 - p. 159 18. Chapter 8 Oral Cavity and COVID-19: Clinical Manifestations, Pathology, and Dental Profession - p. 173 19. Chapter 9 Gastrointestinal Manifestations of COVID-19 - p. 191 20. Chapter 10 Kidney Manifestations of COVID-19 - p. 203 21. Chapter 11 Ophthalmic Manifestations of COVID-19 - p. 218 22. Chapter 12 Psychiatric Manifestations of COVID-19 - p. 226 23. Part III Fetus, Newborn, Infants, Children - p. 234 24. Chapter 13 Impact of Maternal SARS-CoV-2 Infection on the Fetus and Newborn - p. 235 25. Chapter 14 COVID-19 in Children and Adolescents - p. 253 26. Part IV Special Topics: Emergency Medicine, Therapeutics, Novel Targets, Vaccines - p. 267 27. Chapter 15 COVID-19: Emergency Medicine Perspectives - p. 268 28. Chapter 16 Therapeutics for COVID-19 - p. 282 29. Chapter 17 Novel Therapeutic Targets for SARS-CoV-2 and COVID-19 - p. 308 30. Chapter 18 Vaccine Basics and the Development and Rollout of COVID-19 Vaccines - p. 326 31. Glossary - p. 349 32. Acronyms - p. 359 33. Index - p. 364
Written by physicians and scientists with expertise in this evolving area, Textbook of SARS-CoV-2 and COVID-19 provides a coherent, readable, and clinically relevant review of the biology, epidemiology, pathophysiology, immunology, clinical features, current treatment, and prevention strategies for the SARS-CoV-2 virus. Using both a systemic and topic-based approach, it summarizes and clarifies the extensive literature published on SARS-CoV-2 and COVID-19, includes a comprehensive bibliography, and provides answers to clinical questions at the point of care from multiple specialty perspectives.
1. Cover Image - p. i 2. Title Page - p. iii 3. Copyright - p. iv 4. Dedication - p. v 5. Contributors - p. vi 6. Acknowledgments - p. ix 7. Preface - p. x 8. Table of Contents - p. xiii 9. Part I The Basics: Epidemiology, Biology, Pathogenesis, Immunology, and Natural History - p. 1 10. Chapter 1 Epidemiology of SARS-CoV-2 and COVID-19 - p. 2 11. Chapter 2 SARS-CoV-2: Structure, Pathogenesis, and Diagnosis - p. 24 12. Chapter 3 Immunology of COVID-19 - p. 52 13. Chapter 4 COVID-19: Natural History and Spectrum of Disease - p. 72 14. Part II The Clinical: Manifestations in Systems and Domains of the Body - p. 99 15. Chapter 5 Pulmonary Manifestations of COVID-19 - p. 100 16. Chapter 6 COVID-19 and the Cardiovascular System - p. 137 17. Chapter 7 Neurological Manifestations of COVID-19 - p. 159 18. Chapter 8 Oral Cavity and COVID-19: Clinical Manifestations, Pathology, and Dental Profession - p. 173 19. Chapter 9 Gastrointestinal Manifestations of COVID-19 - p. 191 20. Chapter 10 Kidney Manifestations of COVID-19 - p. 203 21. Chapter 11 Ophthalmic Manifestations of COVID-19 - p. 218 22. Chapter 12 Psychiatric Manifestations of COVID-19 - p. 226 23. Part III Fetus, Newborn, Infants, Children - p. 234 24. Chapter 13 Impact of Maternal SARS-CoV-2 Infection on the Fetus and Newborn - p. 235 25. Chapter 14 COVID-19 in Children and Adolescents - p. 253 26. Part IV Special Topics: Emergency Medicine, Therapeutics, Novel Targets, Vaccines - p. 267 27. Chapter 15 COVID-19: Emergency Medicine Perspectives - p. 268 28. Chapter 16 Therapeutics for COVID-19 - p. 282 29. Chapter 17 Novel Therapeutic Targets for SARS-CoV-2 and COVID-19 - p. 308 30. Chapter 18 Vaccine Basics and the Development and Rollout of COVID-19 Vaccines - p. 326 31. Glossary - p. 349 32. Acronyms - p. 359 33. Index - p. 364