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Written by national recognized experts and senior fellows at leading research institutions, including the National Institutes of Health, and edited by Drs. Griffin P. Rodgers and Neal S. Young, The Bethesda Handbook of Clinical Hematology, 5th Edition, is a concise, comprehensive handbook designed for everyday clinical use. Organized in a quick-reference, portable format, it covers the clinical information you need to know for the diagnosis and treatment all of blood and bone marrow disorders. Readable and practical, the Bethesda Handbook features numerous tables, algorithms, illustrations, and bulleted lists throughout to help bridge the gap between cutting-edge science and everyday clinical practice.

1. Cover - p. i 2. Half Title - p. i 3. Title - p. ii 4. Copyright - p. iii 5. Dedication - p. iv 6. Preface - p. v 7. Contributors - p. vi 8. Contents - p. viii 9. Chapter 1 ■ Iron Deficiency - p. x 10. Chapter 2 ■ Deficiencies of Vitamin B12 and Folate - p. 11 11. Chapter 3 ■ Hemolytic Anemia - p. 22 12. Chapter 4 ■ Sickle Cell Anemia and Thalassemia - p. 40 13. Chapter 5 ■ Porphyrias - p. 63 14. Chapter 6 ■ Bone Marrow Failure Syndromes: Aplastic Anemia, Acquired and Constitutional; Paroxysmal Nocturnal Hemoglobinuria; Pure Red Blood Cell Aplasia; and Agranulocytosis - p. 69 15. Chapter 7 ■ Myelodysplastic Syndromes - p. 94 16. Chapter 8 ■ The Myeloproliferative Neoplasms: Polycythemia Vera, Essential Thrombocythemia, Primary Myelofibrosis, and Chronic Myelomonocytic Leukemia - p. 118 17. Chapter 9 ■ Neutrophil Disorders and Neutropenias - p. 135 18. Chapter 10 ■ Childhood Hematologic Diseases - p. 146 19. Chapter 11 ■ Acute Myeloid Leukemia - p. 164 20. Chapter 12 ■ Acute Lymphoblastic Leukemia - p. 185 21. Chapter 13 ■ Chronic Myelogenous Leukemia - p. 199 22. Chapter 14 ■ Chronic Lymphocytic Leukemia - p. 217 23. Chapter 15 ■ Hodgkin Lymphoma - p. 235 24. Chapter 16 ■ Non-Hodgkin Lymphomas - p. 248 25. Chapter 17 ■ Multiple Myeloma - p. 275 26. Chapter 18 ■ Hematopoietic Stem Cell Transplantation - p. 293 27. Chapter 19 ■ Thrombocytopenia - p. 318 28. Chapter 20 ■ Disorders of Hemostasis I: Coagulation - p. 339 29. Chapter 21 ■ Disorders of Hemostasis II - p. 353 30. Chapter 22 ■ Venous Thromboembolism - p. 369 31. Chapter 23 ■ Consultations in Anticoagulation - p. 385 32. Chapter 24 ■ Blood Transfusion - p. 400 33. Chapter 25 ■ Hemochromatosis - p. 437 34. Chapter 26 ■ Consultative Hematology - p. 454 35. Chapter 27 ■ Interpretation of Standard Hematologic Tests - p. 476 36. Chapter 28 ■ Basic Principles and Clinical Applications of Flow Cytometry - p. 501 37. Index - p. 520

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Written by national recognized experts and senior fellows at leading research institutions, including the National Institutes of Health, and edited by Drs. Griffin P. Rodgers and Neal S. Young, The Bethesda Handbook of Clinical Hematology, 5th Edition, is a concise, comprehensive handbook designed for everyday clinical use. Organized in a quick-reference, portable format, it covers the clinical information you need to know for the diagnosis and treatment all of blood and bone marrow disorders. Readable and practical, the Bethesda Handbook features numerous tables, algorithms, illustrations, and bulleted lists throughout to help bridge the gap between cutting-edge science and everyday clinical practice.

1. Cover - p. i 2. Half Title - p. i 3. Title - p. ii 4. Copyright - p. iii 5. Dedication - p. iv 6. Preface - p. v 7. Contributors - p. vi 8. Contents - p. viii 9. Chapter 1 ■ Iron Deficiency - p. x 10. Chapter 2 ■ Deficiencies of Vitamin B12 and Folate - p. 11 11. Chapter 3 ■ Hemolytic Anemia - p. 22 12. Chapter 4 ■ Sickle Cell Anemia and Thalassemia - p. 40 13. Chapter 5 ■ Porphyrias - p. 63 14. Chapter 6 ■ Bone Marrow Failure Syndromes: Aplastic Anemia, Acquired and Constitutional; Paroxysmal Nocturnal Hemoglobinuria; Pure Red Blood Cell Aplasia; and Agranulocytosis - p. 69 15. Chapter 7 ■ Myelodysplastic Syndromes - p. 94 16. Chapter 8 ■ The Myeloproliferative Neoplasms: Polycythemia Vera, Essential Thrombocythemia, Primary Myelofibrosis, and Chronic Myelomonocytic Leukemia - p. 118 17. Chapter 9 ■ Neutrophil Disorders and Neutropenias - p. 135 18. Chapter 10 ■ Childhood Hematologic Diseases - p. 146 19. Chapter 11 ■ Acute Myeloid Leukemia - p. 164 20. Chapter 12 ■ Acute Lymphoblastic Leukemia - p. 185 21. Chapter 13 ■ Chronic Myelogenous Leukemia - p. 199 22. Chapter 14 ■ Chronic Lymphocytic Leukemia - p. 217 23. Chapter 15 ■ Hodgkin Lymphoma - p. 235 24. Chapter 16 ■ Non-Hodgkin Lymphomas - p. 248 25. Chapter 17 ■ Multiple Myeloma - p. 275 26. Chapter 18 ■ Hematopoietic Stem Cell Transplantation - p. 293 27. Chapter 19 ■ Thrombocytopenia - p. 318 28. Chapter 20 ■ Disorders of Hemostasis I: Coagulation - p. 339 29. Chapter 21 ■ Disorders of Hemostasis II - p. 353 30. Chapter 22 ■ Venous Thromboembolism - p. 369 31. Chapter 23 ■ Consultations in Anticoagulation - p. 385 32. Chapter 24 ■ Blood Transfusion - p. 400 33. Chapter 25 ■ Hemochromatosis - p. 437 34. Chapter 26 ■ Consultative Hematology - p. 454 35. Chapter 27 ■ Interpretation of Standard Hematologic Tests - p. 476 36. Chapter 28 ■ Basic Principles and Clinical Applications of Flow Cytometry - p. 501 37. Index - p. 520

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