The Biology of Ageing: From Hallmarks to Drugs provides a series of reviews covering multiple aspects of the translational pipeline as interventions in the biology of ageing itself become a clinical reality. New chapters cover Cellular senescence and NAD+: what are the links?, Biomarker for ageing: potential and pitfalls, What chemists offer to ageing research, You are what you eat – or are you? Exploring dietary versus topical anti-oxidants in skin ageing, Clinical trials: A simple guide for gerontologists, Towards an ethical framework for geroscience, and more.
The book explores links between known ageing mechanisms and new interventions, agents and actions at the nutraceutical-drug divide, the challenges and opportunities provided by biomarkers and chemistry- biology interface and lastly the ethical and operational challenges of clinical trials in the age of translational geroscience.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. ix 7. Chapter One: You are what you eat—Or are you? Exploring dietary versus topical antioxidants in skin aging - p. 9 8. Chapter Two: Clinical trials: A simple guide for gerontologists - p. 55 9. Chapter Three: Toward an ethical framework for geroscience? - p. 71 10. Chapter Four: Selective autophagy-driven senescence as a barrier to tumorigenesis: Arriving at the destination through an alternative path - p. 89
The Biology of Ageing: From Hallmarks to Drugs provides a series of reviews covering multiple aspects of the translational pipeline as interventions in the biology of ageing itself become a clinical reality. New chapters cover Cellular senescence and NAD+: what are the links?, Biomarker for ageing: potential and pitfalls, What chemists offer to ageing research, You are what you eat – or are you? Exploring dietary versus topical anti-oxidants in skin ageing, Clinical trials: A simple guide for gerontologists, Towards an ethical framework for geroscience, and more.
The book explores links between known ageing mechanisms and new interventions, agents and actions at the nutraceutical-drug divide, the challenges and opportunities provided by biomarkers and chemistry- biology interface and lastly the ethical and operational challenges of clinical trials in the age of translational geroscience.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Contributors - p. iii 6. Preface - p. ix 7. Chapter One: You are what you eat—Or are you? Exploring dietary versus topical antioxidants in skin aging - p. 9 8. Chapter Two: Clinical trials: A simple guide for gerontologists - p. 55 9. Chapter Three: Toward an ethical framework for geroscience? - p. 71 10. Chapter Four: Selective autophagy-driven senescence as a barrier to tumorigenesis: Arriving at the destination through an alternative path - p. 89
