The Exposome in Cancer Disparities: Influence of Environmental and Infectious Factors in LMICs examines how environmental and infectious factors drive cancer inequities in low- and middle-income countries (LMICs). The book introduces the exposome as a comprehensive framework to understand complex risk factors, such as environmental toxins, climate change, and infectious agents like HPV and HIV. The book combines scientific insights, real-world case studies, and practical strategies from international experts, highlighting region-specific contributors to cancer disparities. Structured into thematic sections, it offers a holistic view of the challenges faced by LMICs and provides actionable, evidence-based solutions tailored to resource-limited settings.
The work emphasizes the importance of multidisciplinary approaches and international collaboration to develop effective prevention and policy strategies. It will benefit researchers, policymakers, and healthcare professionals by deepening understanding of cancer risk factors, fostering global cooperation and guiding targeted interventions to reduce health inequities and improve outcomes worldwide.
1. Chapter 1 Introduction: The exposome framework and its relevance to cancer disparities - p. 3 2. Chapter 2 Environmental exposures and cancer risk: An exposomics perspective in low- and middle-income countries - p. 31 3. Chapter 3 Infectious agents, HIV, and carcinogenic risks of cancer in low- and middle-income countries - p. 57 4. Chapter 4 Socioeconomic inequities and the exposome: A double burden in low- and middle-income countries - p. 79 5. Part II Mechanisms and intersections of the exposome - p. 99 6. Chapter 5 Neglected tropical diseases, coinfections, and the exposome: The overlapping burden in low- and middle-income countries - p. 101 7. Chapter 6 Climate change, the exposome, and cancer disparities in low- and middle-income countries - p. 117 8. Chapter 7 Culture, society, and the exposome: Understanding cancer risk in low- and middle-income countries - p. 139 9. Chapter 8 Gene–environment interactions: The exposome and cancer susceptibility - p. 157 10. Chapter 9 The microbiome and the exposome: Implications for cancer risk - p. 169 11. Part III Exposome-informed strategies for cancer prevention and equity - p. 195 12. Chapter 10 Cancer prevention in low- and middle-income countries: Targeting environmental and infectious exposures - p. 197 13. Chapter 11 Strengthening healthcare systems through exposomics - p. 217 14. Chapter 12 Policy reform and environmental justice: Bridging gaps in cancer prevention - p. 247 15. Part IV Innovations and global collaboration in exposomics - p. 265 16. Chapter 13 Emerging technologies in exposomics: Advancing cancer diagnosis and treatment - p. 267 17. Chapter 14 Artificial intelligence, big data, and the exposome: Transforming cancer risk assessment - p. 285 18. Chapter 15 Global collaboration in exposomics: A multistakeholder approach to reducing cancer disparities - p. 301 19. Chapter 16 The future of exposomics: Pathways to address cancer disparities in low- and middle-income countries - p. 321 20. Index - p. 329
The Exposome in Cancer Disparities: Influence of Environmental and Infectious Factors in LMICs examines how environmental and infectious factors drive cancer inequities in low- and middle-income countries (LMICs). The book introduces the exposome as a comprehensive framework to understand complex risk factors, such as environmental toxins, climate change, and infectious agents like HPV and HIV. The book combines scientific insights, real-world case studies, and practical strategies from international experts, highlighting region-specific contributors to cancer disparities. Structured into thematic sections, it offers a holistic view of the challenges faced by LMICs and provides actionable, evidence-based solutions tailored to resource-limited settings.
The work emphasizes the importance of multidisciplinary approaches and international collaboration to develop effective prevention and policy strategies. It will benefit researchers, policymakers, and healthcare professionals by deepening understanding of cancer risk factors, fostering global cooperation and guiding targeted interventions to reduce health inequities and improve outcomes worldwide.
1. Chapter 1 Introduction: The exposome framework and its relevance to cancer disparities - p. 3 2. Chapter 2 Environmental exposures and cancer risk: An exposomics perspective in low- and middle-income countries - p. 31 3. Chapter 3 Infectious agents, HIV, and carcinogenic risks of cancer in low- and middle-income countries - p. 57 4. Chapter 4 Socioeconomic inequities and the exposome: A double burden in low- and middle-income countries - p. 79 5. Part II Mechanisms and intersections of the exposome - p. 99 6. Chapter 5 Neglected tropical diseases, coinfections, and the exposome: The overlapping burden in low- and middle-income countries - p. 101 7. Chapter 6 Climate change, the exposome, and cancer disparities in low- and middle-income countries - p. 117 8. Chapter 7 Culture, society, and the exposome: Understanding cancer risk in low- and middle-income countries - p. 139 9. Chapter 8 Gene–environment interactions: The exposome and cancer susceptibility - p. 157 10. Chapter 9 The microbiome and the exposome: Implications for cancer risk - p. 169 11. Part III Exposome-informed strategies for cancer prevention and equity - p. 195 12. Chapter 10 Cancer prevention in low- and middle-income countries: Targeting environmental and infectious exposures - p. 197 13. Chapter 11 Strengthening healthcare systems through exposomics - p. 217 14. Chapter 12 Policy reform and environmental justice: Bridging gaps in cancer prevention - p. 247 15. Part IV Innovations and global collaboration in exposomics - p. 265 16. Chapter 13 Emerging technologies in exposomics: Advancing cancer diagnosis and treatment - p. 267 17. Chapter 14 Artificial intelligence, big data, and the exposome: Transforming cancer risk assessment - p. 285 18. Chapter 15 Global collaboration in exposomics: A multistakeholder approach to reducing cancer disparities - p. 301 19. Chapter 16 The future of exposomics: Pathways to address cancer disparities in low- and middle-income countries - p. 321 20. Index - p. 329
