The Frontal Lobes, Volume 163, updates readers on the latest thinking on the structure and function of the human frontal lobe. Sections address methodology, anatomy, physiology and pharmacology, function, development, aging and disorders, and rehabilitation. Patients with focal lesions in the frontal lobes have long been studied to reveal the organization and function of the frontal lobes. Over the last two decades, studies of patients with neurodegenerative diseases and developmental disorders have increased, with new findings discussed in this volume. In addition, the book includes discussions on genetics and molecular biology, optogenetics, high-resolution structural and functional neuroimaging and electrophysiology, and more.
Lastly, new knowledge on the biology, structure and function of the frontal lobes, new treatment targets for pharmacology, non-invasive brain stimulation, and cognitive/social remediation are presented. The last section covers new efforts that will hopefully lead to better outcomes in patients with frontal lobe disorders.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Handbook of Clinical Neurology 3rd Series - p. v 6. Foreword - p. vii 7. Preface - p. ix 8. Contributors - p. xi 9. Section I: History - p. xi 10. Chapter 1: The prefrontal cortex in the neurology clinic - p. xi 11. Section II: Methods - p. 15 12. Chapter 2: The functions of the frontal lobes: Evidence from patients with focal brain damage - p. 15 13. Chapter 3: Cognitive neurophysiology of the prefrontal cortex - p. 34 14. Chapter 4: Functional imaging - p. 59 15. Chapter 5: Transcranial magnetic stimulation: Neurophysiological and clinical applications - p. 72 16. Section III: Anatomy, physiology and pharmacology - p. 92 17. Chapter 6: The anatomy of the human frontal lobe - p. 92 18. Chapter 7: Dopamine and the motivation of cognitive control - p. 122 19. Section IV: Function of the frontal lobes - p. 143 20. Chapter 8: Frontal lobe syndromes - p. 143 21. Chapter 9: Hierarchical cognitive control and the frontal lobes - p. 164 22. Chapter 10: Hemispheric asymmetry in the prefrontal cortex for complex cognition - p. 177 23. Chapter 11: Executive functions - p. 195 24. Chapter 12: The lateral prefrontal cortex and human long-term memory - p. 219 25. Chapter 13: From ideas to action: The prefrontal–premotor connections that shape motor behavior - p. 235 26. Chapter 14: Emotion regulation across the life span - p. 255 27. Chapter 15: Reward - p. 280 28. Chapter 16: Moral conduct and social behavior - p. 294 29. Chapter 17: Computational models of motivated frontal function - p. 315 30. Chapter 18: Control networks of the frontal lobes - p. 332 31. Section V: Development, aging, and disorders - p. 347 32. Chapter 19: Development of the frontal lobe - p. 347 33. Chapter 20: Aging of the frontal lobe - p. 367 34. Chapter 21: Neurodegenerative disorders of the human frontal lobes - p. 389 35. Chapter 22: Traumatic brain injury and frontal lobe plasticity - p. 410 36. Section VI: Rehabilitation - p. 431 37. Chapter 23: Strengthening goal-directed functioning after traumatic brain injury - p. 431 38. Chapter 24: Experimental social training methods - p. 456 39. Chapter 25: Plasticity and recovery of function - p. 472 40. Index - p. 485
The Frontal Lobes, Volume 163, updates readers on the latest thinking on the structure and function of the human frontal lobe. Sections address methodology, anatomy, physiology and pharmacology, function, development, aging and disorders, and rehabilitation. Patients with focal lesions in the frontal lobes have long been studied to reveal the organization and function of the frontal lobes. Over the last two decades, studies of patients with neurodegenerative diseases and developmental disorders have increased, with new findings discussed in this volume. In addition, the book includes discussions on genetics and molecular biology, optogenetics, high-resolution structural and functional neuroimaging and electrophysiology, and more.
Lastly, new knowledge on the biology, structure and function of the frontal lobes, new treatment targets for pharmacology, non-invasive brain stimulation, and cognitive/social remediation are presented. The last section covers new efforts that will hopefully lead to better outcomes in patients with frontal lobe disorders.
1. Cover image - p. iv 2. Title page - p. iv 3. Table of Contents - p. iv 4. Copyright - p. iv 5. Handbook of Clinical Neurology 3rd Series - p. v 6. Foreword - p. vii 7. Preface - p. ix 8. Contributors - p. xi 9. Section I: History - p. xi 10. Chapter 1: The prefrontal cortex in the neurology clinic - p. xi 11. Section II: Methods - p. 15 12. Chapter 2: The functions of the frontal lobes: Evidence from patients with focal brain damage - p. 15 13. Chapter 3: Cognitive neurophysiology of the prefrontal cortex - p. 34 14. Chapter 4: Functional imaging - p. 59 15. Chapter 5: Transcranial magnetic stimulation: Neurophysiological and clinical applications - p. 72 16. Section III: Anatomy, physiology and pharmacology - p. 92 17. Chapter 6: The anatomy of the human frontal lobe - p. 92 18. Chapter 7: Dopamine and the motivation of cognitive control - p. 122 19. Section IV: Function of the frontal lobes - p. 143 20. Chapter 8: Frontal lobe syndromes - p. 143 21. Chapter 9: Hierarchical cognitive control and the frontal lobes - p. 164 22. Chapter 10: Hemispheric asymmetry in the prefrontal cortex for complex cognition - p. 177 23. Chapter 11: Executive functions - p. 195 24. Chapter 12: The lateral prefrontal cortex and human long-term memory - p. 219 25. Chapter 13: From ideas to action: The prefrontal–premotor connections that shape motor behavior - p. 235 26. Chapter 14: Emotion regulation across the life span - p. 255 27. Chapter 15: Reward - p. 280 28. Chapter 16: Moral conduct and social behavior - p. 294 29. Chapter 17: Computational models of motivated frontal function - p. 315 30. Chapter 18: Control networks of the frontal lobes - p. 332 31. Section V: Development, aging, and disorders - p. 347 32. Chapter 19: Development of the frontal lobe - p. 347 33. Chapter 20: Aging of the frontal lobe - p. 367 34. Chapter 21: Neurodegenerative disorders of the human frontal lobes - p. 389 35. Chapter 22: Traumatic brain injury and frontal lobe plasticity - p. 410 36. Section VI: Rehabilitation - p. 431 37. Chapter 23: Strengthening goal-directed functioning after traumatic brain injury - p. 431 38. Chapter 24: Experimental social training methods - p. 456 39. Chapter 25: Plasticity and recovery of function - p. 472 40. Index - p. 485
