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Dr. Quigley has created a must-have reference on the gut microbiome for the practicing gastroenterologist. A leader in the field of human physiology and digestive disorders, he has laid out the basics on this increasingly important topic, devoting articles to the organization and biology of the human gut microbiome as well as its diagnostic potential. Top international authors have presented articles that discuss the intersection of the gut microbiome and diet and the gut-brain axis. Clinical implications of the gut microbiome are discussed with disease states like IBD, GI cancer, and liver diseases. Finally, the issue ends with the cutting-edge clinical innovation of fecal microbial transplantation. This issue bridges the gap between science and clinical practice and should be an important reference to practicing gastroenterologists.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Basic Definitions and Concepts: Organization of the Gut Microbiome - p. 1 9. From Culture to High-Throughput Sequencing and Beyond: A Layperson’s Guide to the “Omics” and Diagnostic Potential of the Microbiome - p. 9 10. Biology of the Microbiome 1: Interactions with the Host Immune Response - p. 19 11. Biology of the Microbiome 2: Metabolic Role - p. 37 12. Diet and the Microbiome - p. 49 13. Impact of Antibiotics on Necrotizing Enterocolitis and Antibiotic-Associated Diarrhea - p. 61 14. The Microbiome-Gut-Brain Axis in Health and Disease - p. 77 15. The Gut Microbiome in Irritable Bowel Syndrome and Other Functional Bowel Disorders - p. 91 16. Small Intestinal Bacterial Overgrowth and Other Intestinal Disorders - p. 103 17. The Esophageal and Gastric Microbiome in Health and Disease - p. 121 18. The Gut Microbiota in Inflammatory Bowel Disease - p. 143 19. Gut Microbiota and Complications of Liver Disease - p. 155 20. Fecal Microbiota Transplantation - p. 171 21. Index - p. 187

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Dr. Quigley has created a must-have reference on the gut microbiome for the practicing gastroenterologist. A leader in the field of human physiology and digestive disorders, he has laid out the basics on this increasingly important topic, devoting articles to the organization and biology of the human gut microbiome as well as its diagnostic potential. Top international authors have presented articles that discuss the intersection of the gut microbiome and diet and the gut-brain axis. Clinical implications of the gut microbiome are discussed with disease states like IBD, GI cancer, and liver diseases. Finally, the issue ends with the cutting-edge clinical innovation of fecal microbial transplantation. This issue bridges the gap between science and clinical practice and should be an important reference to practicing gastroenterologists.

1. Cover image - p. i 2. Title page - p. i 3. Table of Contents - p. i 4. Copyright - p. ii 5. Contributors - p. iii 6. Forthcoming Issues - p. xi 7. Preface - p. xiii 8. Basic Definitions and Concepts: Organization of the Gut Microbiome - p. 1 9. From Culture to High-Throughput Sequencing and Beyond: A Layperson’s Guide to the “Omics” and Diagnostic Potential of the Microbiome - p. 9 10. Biology of the Microbiome 1: Interactions with the Host Immune Response - p. 19 11. Biology of the Microbiome 2: Metabolic Role - p. 37 12. Diet and the Microbiome - p. 49 13. Impact of Antibiotics on Necrotizing Enterocolitis and Antibiotic-Associated Diarrhea - p. 61 14. The Microbiome-Gut-Brain Axis in Health and Disease - p. 77 15. The Gut Microbiome in Irritable Bowel Syndrome and Other Functional Bowel Disorders - p. 91 16. Small Intestinal Bacterial Overgrowth and Other Intestinal Disorders - p. 103 17. The Esophageal and Gastric Microbiome in Health and Disease - p. 121 18. The Gut Microbiota in Inflammatory Bowel Disease - p. 143 19. Gut Microbiota and Complications of Liver Disease - p. 155 20. Fecal Microbiota Transplantation - p. 171 21. Index - p. 187

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