The Liver: Oxidative Stress and Dietary Antioxidants takes a novel approach to the science of oxidative stress in liver disease by recognizing that diseases are multifactorial and oxidative stress is a single component. It highlights oxidative stress in relation to other processes, such as apoptosis, cell signaling and receptor mediated responses, and includes the therapeutic usage of natural antioxidants in the diet and food matrix, along with coverage of pharmacological and natural agents designed to counteract oxidative stress. Written for research scientists, gastroenterologists, food scientists, hepatologists and physicians, this trans-disciplinary guide will help advance medical sciences and enable new preventative and treatment strategies.
1. Cover - p. i 2. Title page - p. iii 3. Table of Contents - p. iii 4. Copyright - p. ii 5. List of Contributors - p. iv 6. Chapter 1: Oxidative Stress in Hepatitis C Infection - p. xii 7. Chapter 2: Role of Paraoxonase 1 as an Antioxidant in Nonalcoholic Steatohepatitis - p. 13 8. Chapter 3: Alterations in Nucleocytoplasmic Localization of the Methionine Cycle Induced by Oxidative Stress During Liver Disease - p. 20 9. Chapter 4: Oxidative Stress in Iron Toxicity of the Liver - p. 41 10. Chapter 5: Cardiac Glycosides and Oxidative Stress in Liver Cancer - p. 54 11. Chapter 6: Acetaldehyde Effects on Cellular Redox State - p. 61 12. Chapter 7: The Role of Glyoxalase-I in Oxidant Stress of Liver Damage - p. 70 13. Chapter 8: Reactive Oxygen and Nitrogen Species and Liver Ischemia-Reperfusion Injury: An Overview - p. 78 14. Chapter 9: Reactive Oxygen and Nitrogen Species and Liver Ischemia- Reperfusion Injury: Role of Glutamine - p. 96 15. Chapter 10: Reactive Oxygen and Nitrogen Species and Liver Ischemia-Reperfusion Injury: Role of Lipoic Acid - p. 107 16. Chapter 11: Oxidative Stress as a Crucial Factor in Liver Associated Disorders: Potential Therapeutic Effect of Antioxidants - p. 119 17. Chapter 12: l-NAME as a Synthetic Antioxidant in Liver Injuries - p. 130 18. Chapter 13: Chemoprotective Role of Vitamin C in Liver Diseases - p. 137 19. Chapter 14: Protective Role of Lycopene Against Oxidative Stress in Liver - p. 153 20. Chapter 15: Vitamin E Protection Against Hyperthyroidism-Induced Liver Oxidative Stress - p. 167 21. Chapter 16: Citric Acid an Antioxidant in Liver - p. 181 22. Chapter 17: Resveratrol and Protection in Hepatic Steatosis: Antioxidant Effects - p. 198 23. Chapter 18: Astaxanthin, a Marine Carotenoid Against Hepatic Oxidative Stress: a Systematic Review - p. 209 24. Chapter 19: Effect of Melatonin as an Antioxidant in the Liver - p. 228 25. Chapter 20: The Liver: Oxidative Stress and Dietary Antioxidants - p. 237 26. Chapter 21: Endogenous Mitochondrial Aldehyde Dehydrogenase-2 as an Antioxidant in Liver - p. 246 27. Chapter 22: Comparing Antioxidants in Liver Disease: l-Carnitine, N-Acetylcysteine, and Genistein - p. 259 28. Chapter 23: The Hepatoprotective Effects of Coenzyme Q10 Against Oxidative Stress - p. 279 29. Chapter 24: Carnosine as a Putative Antioxidant in Usage Against Liver Disease - p. 294 30. Chapter 25: Dioscin as a Natural Saponin and Protection in Oxidative Stress in Hepatic Fibrosis - p. 304 31. Chapter 26: Gallic Acid as a Putative Antioxidant in Usage Against Liver Disease - p. 316 32. Chapter 27: Oleuropein as an Antioxidant and Liver Protect - p. 322 33. Chapter 28: Garlic and Liver Diseases - p. 335 34. Index - p. 347
The Liver: Oxidative Stress and Dietary Antioxidants takes a novel approach to the science of oxidative stress in liver disease by recognizing that diseases are multifactorial and oxidative stress is a single component. It highlights oxidative stress in relation to other processes, such as apoptosis, cell signaling and receptor mediated responses, and includes the therapeutic usage of natural antioxidants in the diet and food matrix, along with coverage of pharmacological and natural agents designed to counteract oxidative stress. Written for research scientists, gastroenterologists, food scientists, hepatologists and physicians, this trans-disciplinary guide will help advance medical sciences and enable new preventative and treatment strategies.
1. Cover - p. i 2. Title page - p. iii 3. Table of Contents - p. iii 4. Copyright - p. ii 5. List of Contributors - p. iv 6. Chapter 1: Oxidative Stress in Hepatitis C Infection - p. xii 7. Chapter 2: Role of Paraoxonase 1 as an Antioxidant in Nonalcoholic Steatohepatitis - p. 13 8. Chapter 3: Alterations in Nucleocytoplasmic Localization of the Methionine Cycle Induced by Oxidative Stress During Liver Disease - p. 20 9. Chapter 4: Oxidative Stress in Iron Toxicity of the Liver - p. 41 10. Chapter 5: Cardiac Glycosides and Oxidative Stress in Liver Cancer - p. 54 11. Chapter 6: Acetaldehyde Effects on Cellular Redox State - p. 61 12. Chapter 7: The Role of Glyoxalase-I in Oxidant Stress of Liver Damage - p. 70 13. Chapter 8: Reactive Oxygen and Nitrogen Species and Liver Ischemia-Reperfusion Injury: An Overview - p. 78 14. Chapter 9: Reactive Oxygen and Nitrogen Species and Liver Ischemia- Reperfusion Injury: Role of Glutamine - p. 96 15. Chapter 10: Reactive Oxygen and Nitrogen Species and Liver Ischemia-Reperfusion Injury: Role of Lipoic Acid - p. 107 16. Chapter 11: Oxidative Stress as a Crucial Factor in Liver Associated Disorders: Potential Therapeutic Effect of Antioxidants - p. 119 17. Chapter 12: l-NAME as a Synthetic Antioxidant in Liver Injuries - p. 130 18. Chapter 13: Chemoprotective Role of Vitamin C in Liver Diseases - p. 137 19. Chapter 14: Protective Role of Lycopene Against Oxidative Stress in Liver - p. 153 20. Chapter 15: Vitamin E Protection Against Hyperthyroidism-Induced Liver Oxidative Stress - p. 167 21. Chapter 16: Citric Acid an Antioxidant in Liver - p. 181 22. Chapter 17: Resveratrol and Protection in Hepatic Steatosis: Antioxidant Effects - p. 198 23. Chapter 18: Astaxanthin, a Marine Carotenoid Against Hepatic Oxidative Stress: a Systematic Review - p. 209 24. Chapter 19: Effect of Melatonin as an Antioxidant in the Liver - p. 228 25. Chapter 20: The Liver: Oxidative Stress and Dietary Antioxidants - p. 237 26. Chapter 21: Endogenous Mitochondrial Aldehyde Dehydrogenase-2 as an Antioxidant in Liver - p. 246 27. Chapter 22: Comparing Antioxidants in Liver Disease: l-Carnitine, N-Acetylcysteine, and Genistein - p. 259 28. Chapter 23: The Hepatoprotective Effects of Coenzyme Q10 Against Oxidative Stress - p. 279 29. Chapter 24: Carnosine as a Putative Antioxidant in Usage Against Liver Disease - p. 294 30. Chapter 25: Dioscin as a Natural Saponin and Protection in Oxidative Stress in Hepatic Fibrosis - p. 304 31. Chapter 26: Gallic Acid as a Putative Antioxidant in Usage Against Liver Disease - p. 316 32. Chapter 27: Oleuropein as an Antioxidant and Liver Protect - p. 322 33. Chapter 28: Garlic and Liver Diseases - p. 335 34. Index - p. 347
