The Metallome in Motion: Insights into Ecosystem and Food Chain Toxicodynamics fills a vital gap by integrating multidisciplinary research on how metals influence biological systems, food safety, and environmental health. The book’s contents span a wide range of interrelated topics, beginning with metal-mediated epigenetic modifications and toxicodynamics at the molecular and cellular levels. Other sections explore the geochemical and anthropogenic origins of contaminants, factors affecting metal bioavailability, and the synergistic effects of metal-radical interactions. In addition, detailed chapters address the roles of metalloproteins, pathways of bioaccumulation and trophic transfer, transgenerational toxicity, and hidden reservoirs such as soil microaggregates.
Advanced analytical methods, the emerging field of toxicometallomics, impacts of metals in agriculture, quantum effects of nanoparticles, and global regulatory frameworks are also thoroughly discussed, making this an essential reference for postgraduate students in food science, as well as academics and researchers in agriculture, plant science, environmental science, and biotechnology.
1. Title of Book - p. i 2. Cover Image - p. i 3. Title Page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Dedication - p. v 7. Contributors - p. xxiii 8. About the editors - p. xxvii 9. Foreword - p. xxxi 10. Preface - p. xxxiii 11. Acknowledgments - p. xxxv 12. About the book - p. xxxvii 13. Chapter 1 Metal-mediated epigenetic modifications: Implications for food chain toxicodynamics - p. 1 14. Chapter 2 Toxicodynamics of metals: Molecular and cellular mechanisms - p. 23 15. Chapter 3 Geochemical and anthropogenic sources of metal contaminants - p. 51 16. Chapter 4 Metal bioavailability: Speciation, complexation, and redox dynamics - p. 95 17. Chapter 5 Metal–radical interactions: Synergistic effects on food chain toxicodynamics - p. 113 18. Chapter 6 Metalloproteins and metallochaperones: Functional roles in toxicodynamic - p. 131 19. Chapter 7 Transgenerational effects of metal toxicity in aquatic and terrestrial organisms - p. 153 20. Chapter 8 Hidden metal reservoirs in the food chain: Soil microaggregates as metal sinks - p. 193 21. Chapter 9 Advanced analytical approaches in metallome profiling - p. 233 22. Chapter 10 Toxicometallomics: Linking metal exposure to biomarkers in humans - p. 261 23. Chapter 11 Metal-mediated disruption of cellular homeostasis in the food chain - p. 293 24. Chapter 12 Metals in agricultural systems: Uptake, translocation, and accumulation - p. 305 25. Chapter 13 Quantum effects of metal nanoparticles on cellular toxicodynamics - p. 325 26. Chapter 14 Risk assessment and modeling of metal transfer in food chains - p. 339 27. Chapter 15 Chronic dietary metal exposure: Mechanisms of toxicity and implications for human health - p. 359 28. Chapter 16 Regulation of metal contaminants in food and ecosystems: Global perspectives - p. 389 29. Chapter 17 Metallotoxicant-driven cellular dysregulation: Redox pathways in stress signalling and death program execution - p. 429 30. Chapter 18 Intensive cropping systems reduce heavy metals in cotton fields - p. 463 31. Chapter 19 Molecular toxicology of metal exposure: Oxidative stress induction and cytotoxic mechanistic pathways - p. 483 32. Chapter 20 Molecular mechanism of metal-induced oxidative stress and cytotoxicity - p. 515 33. Chapter 21 Metal-binding proteins in toxicodynamics: Functional roles of metalloproteins and metallochaperones - p. 539 34. Index - p. 559
The Metallome in Motion: Insights into Ecosystem and Food Chain Toxicodynamics fills a vital gap by integrating multidisciplinary research on how metals influence biological systems, food safety, and environmental health. The book’s contents span a wide range of interrelated topics, beginning with metal-mediated epigenetic modifications and toxicodynamics at the molecular and cellular levels. Other sections explore the geochemical and anthropogenic origins of contaminants, factors affecting metal bioavailability, and the synergistic effects of metal-radical interactions. In addition, detailed chapters address the roles of metalloproteins, pathways of bioaccumulation and trophic transfer, transgenerational toxicity, and hidden reservoirs such as soil microaggregates.
Advanced analytical methods, the emerging field of toxicometallomics, impacts of metals in agriculture, quantum effects of nanoparticles, and global regulatory frameworks are also thoroughly discussed, making this an essential reference for postgraduate students in food science, as well as academics and researchers in agriculture, plant science, environmental science, and biotechnology.
1. Title of Book - p. i 2. Cover Image - p. i 3. Title Page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Dedication - p. v 7. Contributors - p. xxiii 8. About the editors - p. xxvii 9. Foreword - p. xxxi 10. Preface - p. xxxiii 11. Acknowledgments - p. xxxv 12. About the book - p. xxxvii 13. Chapter 1 Metal-mediated epigenetic modifications: Implications for food chain toxicodynamics - p. 1 14. Chapter 2 Toxicodynamics of metals: Molecular and cellular mechanisms - p. 23 15. Chapter 3 Geochemical and anthropogenic sources of metal contaminants - p. 51 16. Chapter 4 Metal bioavailability: Speciation, complexation, and redox dynamics - p. 95 17. Chapter 5 Metal–radical interactions: Synergistic effects on food chain toxicodynamics - p. 113 18. Chapter 6 Metalloproteins and metallochaperones: Functional roles in toxicodynamic - p. 131 19. Chapter 7 Transgenerational effects of metal toxicity in aquatic and terrestrial organisms - p. 153 20. Chapter 8 Hidden metal reservoirs in the food chain: Soil microaggregates as metal sinks - p. 193 21. Chapter 9 Advanced analytical approaches in metallome profiling - p. 233 22. Chapter 10 Toxicometallomics: Linking metal exposure to biomarkers in humans - p. 261 23. Chapter 11 Metal-mediated disruption of cellular homeostasis in the food chain - p. 293 24. Chapter 12 Metals in agricultural systems: Uptake, translocation, and accumulation - p. 305 25. Chapter 13 Quantum effects of metal nanoparticles on cellular toxicodynamics - p. 325 26. Chapter 14 Risk assessment and modeling of metal transfer in food chains - p. 339 27. Chapter 15 Chronic dietary metal exposure: Mechanisms of toxicity and implications for human health - p. 359 28. Chapter 16 Regulation of metal contaminants in food and ecosystems: Global perspectives - p. 389 29. Chapter 17 Metallotoxicant-driven cellular dysregulation: Redox pathways in stress signalling and death program execution - p. 429 30. Chapter 18 Intensive cropping systems reduce heavy metals in cotton fields - p. 463 31. Chapter 19 Molecular toxicology of metal exposure: Oxidative stress induction and cytotoxic mechanistic pathways - p. 483 32. Chapter 20 Molecular mechanism of metal-induced oxidative stress and cytotoxicity - p. 515 33. Chapter 21 Metal-binding proteins in toxicodynamics: Functional roles of metalloproteins and metallochaperones - p. 539 34. Index - p. 559
