This volume of Progress in Molecular Biology and Translational Science discusses cutting-edge research of proteasomes and proteasome-associated proteins and cellular systems. The volume is split into two sections. The first part discusses the current knowledge of the structure, function, and regulation of the proteasomal system. The second part describes the role of the proteasome in aging and disease.
Key features:
* Contributions from leading authorities * Informs and updates on all the latest developments in the field
1. Cover image 2. Table of Contents 3. Copyright 4. Contributors 5. Preface 6. Chapter 1 Structure of the Proteasome 7. Chapter 2 Structure and Function of the Ubiquitin–Proteasome System 8. Chapter 3 Immunoproteasomes 9. Chapter 4 Interactions of the Proteasomal System with Chaperones 10. Chapter 5 Proteasome Inhibitors 11. Chapter 6 Degradation of Damaged Proteins 12. Chapter 7 Changes of the Proteasomal System During the Aging Process 13. Chapter 8 Proteasome and Cancer 14. Chapter 9 The Ubiquitin–Proteasome System and Cardiovascular Disease 15. Chapter 10 Role of the Ubiquitin–Proteasome in Protein Quality Control and Signaling 16. Chapter 11 Proteasome and Neurodegeneratıve Diseases 17. Index
This volume of Progress in Molecular Biology and Translational Science discusses cutting-edge research of proteasomes and proteasome-associated proteins and cellular systems. The volume is split into two sections. The first part discusses the current knowledge of the structure, function, and regulation of the proteasomal system. The second part describes the role of the proteasome in aging and disease.
Key features:
* Contributions from leading authorities * Informs and updates on all the latest developments in the field
1. Cover image 2. Table of Contents 3. Copyright 4. Contributors 5. Preface 6. Chapter 1 Structure of the Proteasome 7. Chapter 2 Structure and Function of the Ubiquitin–Proteasome System 8. Chapter 3 Immunoproteasomes 9. Chapter 4 Interactions of the Proteasomal System with Chaperones 10. Chapter 5 Proteasome Inhibitors 11. Chapter 6 Degradation of Damaged Proteins 12. Chapter 7 Changes of the Proteasomal System During the Aging Process 13. Chapter 8 Proteasome and Cancer 14. Chapter 9 The Ubiquitin–Proteasome System and Cardiovascular Disease 15. Chapter 10 Role of the Ubiquitin–Proteasome in Protein Quality Control and Signaling 16. Chapter 11 Proteasome and Neurodegeneratıve Diseases 17. Index
