The Science of the Brain: Function, Dysfunction and Disease is an innovative exploration into the complex interplay between brain functionality and various neurological disorders, meticulously compiled by a world-renowned researcher. This groundbreaking book presents a comprehensive analysis, offering the first complete theories for eleven major brain disorders, including Alzheimer’s, schizophrenia, and autism spectrum disorder, among others. Each chapter delves into a unique theoretical framework, from lipid raft theories to sympathetic nervous system impacts, all while proposing potential treatment targets grounded in established scientific data. In addition to two chapters that lay the groundwork for understanding brain adaptability and anatomy, other chapters independently dissect each disorder, revealing fresh insights that promise to invigorate research and clinical application. This essential resource not only serves neuroscientists and clinicians seeking a deeper understanding of brain disorders but also invites entrepreneurs interested in novel therapeutic avenues. With its rich references and pioneering theories, this book is poised to become indispensable to students, researchers and clinicians, paving the way for future discoveries in brain health and disease management.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Foreword - p. xi 7. The science of the brain - p. xiii 8. Acknowledgements - p. xxi 9. Chapter 1: A CRH2-ACTH theory of autism spectrum disorder - p. 1 10. Chapter 2: A CRH2-CRH1 theory of anorexia and bulimia - p. 29 11. Chapter 3: A polyunsaturated fatty acid (PUFA) theory of schizophrenia - p. 47 12. Chapter 4: A dynorphin theory of depression and bipolar disorder - p. 95 13. Chapter 5: A CRH-HCN theory of obsessive-compulsive disorder (OCD) - p. 121 14. Chapter 6: A KATP channel theory of attention-deficit hyperactivity disorder - p. 131 15. Chapter 7: A sympathetic nervous system theory of migraine - p. 141 16. Chapter 8: A ceramide theory of multiple sclerosis - p. 161 17. Chapter 9: A calcium channel α2δ subunit theory of amyotrophic lateral sclerosis and frontotemporal dementia - p. 177 18. Chapter 10: A galactose theory of Parkinson's disease - p. 211 19. Chapter 11: A lipid-raft theory of Alzheimer's disease - p. 229 20. Chapter 12: The brain's adaptive response process: function and anatomy - p. 265 21. Chapter 13: The brain's ‘Allow, Restrain, Amplify, Respond’ (ARAR) architecture - p. 285 22. Chapter 14: A comprehensive biological theory of sleep - p. 301 23. Index - p. 329
The Science of the Brain: Function, Dysfunction and Disease is an innovative exploration into the complex interplay between brain functionality and various neurological disorders, meticulously compiled by a world-renowned researcher. This groundbreaking book presents a comprehensive analysis, offering the first complete theories for eleven major brain disorders, including Alzheimer’s, schizophrenia, and autism spectrum disorder, among others. Each chapter delves into a unique theoretical framework, from lipid raft theories to sympathetic nervous system impacts, all while proposing potential treatment targets grounded in established scientific data. In addition to two chapters that lay the groundwork for understanding brain adaptability and anatomy, other chapters independently dissect each disorder, revealing fresh insights that promise to invigorate research and clinical application. This essential resource not only serves neuroscientists and clinicians seeking a deeper understanding of brain disorders but also invites entrepreneurs interested in novel therapeutic avenues. With its rich references and pioneering theories, this book is poised to become indispensable to students, researchers and clinicians, paving the way for future discoveries in brain health and disease management.
1. Title of Book - p. i 2. Cover image - p. i 3. Title page - p. ii 4. Table of Contents - p. iii 5. Copyright - p. iv 6. Foreword - p. xi 7. The science of the brain - p. xiii 8. Acknowledgements - p. xxi 9. Chapter 1: A CRH2-ACTH theory of autism spectrum disorder - p. 1 10. Chapter 2: A CRH2-CRH1 theory of anorexia and bulimia - p. 29 11. Chapter 3: A polyunsaturated fatty acid (PUFA) theory of schizophrenia - p. 47 12. Chapter 4: A dynorphin theory of depression and bipolar disorder - p. 95 13. Chapter 5: A CRH-HCN theory of obsessive-compulsive disorder (OCD) - p. 121 14. Chapter 6: A KATP channel theory of attention-deficit hyperactivity disorder - p. 131 15. Chapter 7: A sympathetic nervous system theory of migraine - p. 141 16. Chapter 8: A ceramide theory of multiple sclerosis - p. 161 17. Chapter 9: A calcium channel α2δ subunit theory of amyotrophic lateral sclerosis and frontotemporal dementia - p. 177 18. Chapter 10: A galactose theory of Parkinson's disease - p. 211 19. Chapter 11: A lipid-raft theory of Alzheimer's disease - p. 229 20. Chapter 12: The brain's adaptive response process: function and anatomy - p. 265 21. Chapter 13: The brain's ‘Allow, Restrain, Amplify, Respond’ (ARAR) architecture - p. 285 22. Chapter 14: A comprehensive biological theory of sleep - p. 301 23. Index - p. 329
