Theranostic Approach for Pancreatic Cancer modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property through introducing new strategies and drugs for tackling the disease. It brings information about ongoing research as well as clinical data about pancreatic cancer and provides detailed descriptions about diagnostic and therapeutic options for easy understanding. The book discusses several topics related to pancreatic cancer, such as stem cells, drug resistance and pancreatic tumor microenvironment, the latest developments in chemotherapy for metastatic cancer and chemoprevention, and epigenome as a therapeutic strategy.
Additionally, it encompasses a discussion on theranostic clinical applications for personalized treatment and management of pancreatic cancer. The book is a valuable resource for cancer researchers, oncologists, and several members of the biomedical field who need to understand more about the diagnosis and treatment of pancreatic cancer.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Dedication - p. v 6. Contributors - p. xv 7. About the editors - p. xix 8. Preface - p. xxi 9. Chapter 1. Biology, pathophysiology, and epidemiology of pancreatic cancer - p. 1 10. Chapter 2. Diagnosis of pancreatic cancer - p. 51 11. Chapter 3. Current knowledge on drug resistance and therapeutic approaches to eliminate pancreatic cancer stem cells - p. 69 12. Chapter 4. Drug resistance and microenvironment in pancreatic cancer - p. 81 13. Chapter 5. The role of the tumor microenvironment in the metastasis of pancreatic cancer and immunotherapy - p. 97 14. Chapter 6. Latest developments in chemotherapy for metastatic pancreatic cancer - p. 111 15. Chapter 7. Genetic manipulations with chemotherapy in pancreatic cancer - p. 141 16. Chapter 8. Genetic predisposition for pancreatic cancer - p. 153 17. Chapter 9. Pancreatic cancer resistance to chemotherapy: resensitization strategies using resveratrol - p. 171 18. Chapter 10. Anticancer activity of a small molecule, tolfenamic acid: an emphasis on pancreatic cancer - p. 195 19. Chapter 11. Targeting the epigenome as a therapeutic strategy for pancreatic tumors: noncoding RNAs and chromatin remodelers - p. 211 20. Chapter 12. Pancreatic cancer chemoprevention: a review on molecular pathways involved in carcinogenesis and targeting with terpenoids, and new potential antitumor drugs - p. 245 21. Chapter 13. Meta-analysis of MTHFR polymorphisms and pancreatic cancer susceptibility - p. 263 22. Chapter 14. Therapeutic vaccines for pancreatic cancer - p. 275 23. Chapter 15. Epidermal growth factor receptor role in pancreatic cancer - p. 295 24. Chapter 16. Recent advances in molecular diagnostics and therapeutic targets for pancreatic cancer - p. 325 25. Index - p. 369
Theranostic Approach for Pancreatic Cancer modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property through introducing new strategies and drugs for tackling the disease. It brings information about ongoing research as well as clinical data about pancreatic cancer and provides detailed descriptions about diagnostic and therapeutic options for easy understanding. The book discusses several topics related to pancreatic cancer, such as stem cells, drug resistance and pancreatic tumor microenvironment, the latest developments in chemotherapy for metastatic cancer and chemoprevention, and epigenome as a therapeutic strategy.
Additionally, it encompasses a discussion on theranostic clinical applications for personalized treatment and management of pancreatic cancer. The book is a valuable resource for cancer researchers, oncologists, and several members of the biomedical field who need to understand more about the diagnosis and treatment of pancreatic cancer.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. Dedication - p. v 6. Contributors - p. xv 7. About the editors - p. xix 8. Preface - p. xxi 9. Chapter 1. Biology, pathophysiology, and epidemiology of pancreatic cancer - p. 1 10. Chapter 2. Diagnosis of pancreatic cancer - p. 51 11. Chapter 3. Current knowledge on drug resistance and therapeutic approaches to eliminate pancreatic cancer stem cells - p. 69 12. Chapter 4. Drug resistance and microenvironment in pancreatic cancer - p. 81 13. Chapter 5. The role of the tumor microenvironment in the metastasis of pancreatic cancer and immunotherapy - p. 97 14. Chapter 6. Latest developments in chemotherapy for metastatic pancreatic cancer - p. 111 15. Chapter 7. Genetic manipulations with chemotherapy in pancreatic cancer - p. 141 16. Chapter 8. Genetic predisposition for pancreatic cancer - p. 153 17. Chapter 9. Pancreatic cancer resistance to chemotherapy: resensitization strategies using resveratrol - p. 171 18. Chapter 10. Anticancer activity of a small molecule, tolfenamic acid: an emphasis on pancreatic cancer - p. 195 19. Chapter 11. Targeting the epigenome as a therapeutic strategy for pancreatic tumors: noncoding RNAs and chromatin remodelers - p. 211 20. Chapter 12. Pancreatic cancer chemoprevention: a review on molecular pathways involved in carcinogenesis and targeting with terpenoids, and new potential antitumor drugs - p. 245 21. Chapter 13. Meta-analysis of MTHFR polymorphisms and pancreatic cancer susceptibility - p. 263 22. Chapter 14. Therapeutic vaccines for pancreatic cancer - p. 275 23. Chapter 15. Epidermal growth factor receptor role in pancreatic cancer - p. 295 24. Chapter 16. Recent advances in molecular diagnostics and therapeutic targets for pancreatic cancer - p. 325 25. Index - p. 369
