Translating microRNA to the Clinic reviews the possibilities of current methodological tools and experimental approaches used by leading translational researchers. The book features the uses of micro ribonucleic acid as deployed in cancer targeting in biomarkers, diabetes, cardiovascular disease, and neurodegeneration, among many others.
Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field, promoting a cross-disciplinary communication between the sub-specialities of medicine, but in common with other books on the topic. In addition, the book emphasizes recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. List of Contributors - p. xi 6. Chapter 1. MicroRNAs: Mirrors of Health and Disease - p. 1 7. Chapter 2. Clinical and Therapeutic Applications of MicroRNA in Cancer - p. 17 8. Chapter 3. MicroRNAs in Kidney Function and Disease - p. 39 9. Chapter 4. MicroRNAs in the Pathogenesis, Diagnosis, and Treatment of Liver Disease - p. 55 10. Chapter 5. Clinical Application of MicroRNAs in Liver Diseases - p. 93 11. Chapter 6. MicroRNAs in Inflammatory Lung Disease - p. 135 12. Chapter 7. MicroRNAs in Idiopathic Pulmonary Fibrosis: Partners in Health and Disease - p. 179 13. Chapter 8. MicroRNA as Biomarkers of Malignant Mesothelioma - p. 203 14. Chapter 9. MicroRNA, an Important Epigenetic Regulator of Immunity and Autoimmunity - p. 223 15. Chapter 10. MicroRNA-Linked Heart Disease and Therapeutic Potential - p. 259 16. Chapter 11. The Clinical Potential of Heart Failure–Related miRNAs - p. 283 17. Chapter 12. The Role of Noncoding RNAs in Prostate Cancer - p. 329 18. Index - p. 371
Translating microRNA to the Clinic reviews the possibilities of current methodological tools and experimental approaches used by leading translational researchers. The book features the uses of micro ribonucleic acid as deployed in cancer targeting in biomarkers, diabetes, cardiovascular disease, and neurodegeneration, among many others.
Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field, promoting a cross-disciplinary communication between the sub-specialities of medicine, but in common with other books on the topic. In addition, the book emphasizes recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole.
1. Cover image - p. i 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. List of Contributors - p. xi 6. Chapter 1. MicroRNAs: Mirrors of Health and Disease - p. 1 7. Chapter 2. Clinical and Therapeutic Applications of MicroRNA in Cancer - p. 17 8. Chapter 3. MicroRNAs in Kidney Function and Disease - p. 39 9. Chapter 4. MicroRNAs in the Pathogenesis, Diagnosis, and Treatment of Liver Disease - p. 55 10. Chapter 5. Clinical Application of MicroRNAs in Liver Diseases - p. 93 11. Chapter 6. MicroRNAs in Inflammatory Lung Disease - p. 135 12. Chapter 7. MicroRNAs in Idiopathic Pulmonary Fibrosis: Partners in Health and Disease - p. 179 13. Chapter 8. MicroRNA as Biomarkers of Malignant Mesothelioma - p. 203 14. Chapter 9. MicroRNA, an Important Epigenetic Regulator of Immunity and Autoimmunity - p. 223 15. Chapter 10. MicroRNA-Linked Heart Disease and Therapeutic Potential - p. 259 16. Chapter 11. The Clinical Potential of Heart Failure–Related miRNAs - p. 283 17. Chapter 12. The Role of Noncoding RNAs in Prostate Cancer - p. 329 18. Index - p. 371
