Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a valuable source for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in tumor progression and blood vessels.
1. Cover image - p. Cover 2. Title page - p. iii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. List of contributors - p. ix 6. Preface - p. xi 7. Chapter 1. Sprouting and nonsprouting angiogenesis in tumors - p. 1 8. Chapter 2. Nonangiogenic tumor growth - p. 15 9. Chapter 3. Vascular co-option - p. 33 10. Chapter 4. Pericyte mimicry: an embryogenesis-derived program of extravascular tumor cell migration - p. 49 11. Chapter 5. Vasculogenic mimicry - p. 89 12. Chapter 6. Postnatal vasculogenesis - p. 101 13. Chapter 7. The perivascular niche - p. 113 14. Chapter 8. Zebrafish embryo as an experimental model to study tumor angiogenesis - p. 129 15. Chapter 9. Clinical strategies to inhibit tumor vascularization - p. 147 16. Index - p. 177
Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a valuable source for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in tumor progression and blood vessels.
1. Cover image - p. Cover 2. Title page - p. iii 3. Table of Contents - p. iii 4. Copyright - p. iv 5. List of contributors - p. ix 6. Preface - p. xi 7. Chapter 1. Sprouting and nonsprouting angiogenesis in tumors - p. 1 8. Chapter 2. Nonangiogenic tumor growth - p. 15 9. Chapter 3. Vascular co-option - p. 33 10. Chapter 4. Pericyte mimicry: an embryogenesis-derived program of extravascular tumor cell migration - p. 49 11. Chapter 5. Vasculogenic mimicry - p. 89 12. Chapter 6. Postnatal vasculogenesis - p. 101 13. Chapter 7. The perivascular niche - p. 113 14. Chapter 8. Zebrafish embryo as an experimental model to study tumor angiogenesis - p. 129 15. Chapter 9. Clinical strategies to inhibit tumor vascularization - p. 147 16. Index - p. 177
