Uropathology
1. Cover image - p. cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Dedication - p. v 6. Contributors - p. vi 7. Preface - p. vii 8. List of Tables - p. vii 9. List of Illustrations - p. vii 10. A. Nonneoplastic Disease of the Prostate - p. vii 11. 1. Anatomy and histology of the prostate - p. vii 12. 2. Seminal vesicle/ejaculatory duct - p. 6 13. 3. Cowper gland - p. 9 14. 4. Benign prostatic hyperplasia - p. 11 15. 5. Acute inflammation of the prostate - p. 14 16. 6. Chronic inflammation of the prostate - p. 16 17. 7. Nonspecific granulomatous prostatitis - p. 18 18. 8. Post-biopsy granuloma - p. 20 19. 9. Prostatic xanthoma - p. 21 20. 10. Granulomatous prostatitis of infectious etiology - p. 22 21. 11. Simple atrophy - p. 24 22. 12. Cystic atrophy - p. 25 23. 13. Postatrophy hyperplasia - p. 26 24. 14. Partial atrophy - p. 28 25. 15. Adenosis - p. 30 26. 16. Sclerosing adenosis - p. 32 27. 17. Clear cell cribriform hyperplasia - p. 35 28. 18. Hyperplasia of mesonephric remnants - p. 37 29. 19. Basal cell hyperplasia - p. 39 30. 20. Urothelial metaplasia - p. 42 31. 21. Squamous metaplasia - p. 43 32. 22. Mucin cell metaplasia - p. 44 33. 23. Neuroendocrine cells involving the prostate - p. 45 34. 24. Verumontanum mucosal gland hyperplasia - p. 47 35. 25. Prostatic infarct - p. 48 36. B. Neoplastic Disease of the Prostate - p. 50 37. 26. High-grade prostatic intraepithelial neoplasia (HGPIN) - p. 50 38. 27. Intraductal carcinoma of the prostate - p. 55 39. 28. Prostatic carcinoma, usual variant - p. 58 40. 29. Prostatic carcinoma, atrophic variant - p. 65 41. 30. Prostatic carcinoma, foamy gland variant - p. 67 42. 31. Prostatic carcinoma, pseudohyperplastic variant - p. 69 43. 32. Prostatic carcinoma, mucinous variant - p. 72 44. 33. Prostatic carcinoma, microcystic variant - p. 74 45. 34. Prostatic intraepithelial neoplasia (PIN)-like adenocarcinoma - p. 77 46. 35. Sarcomatoid carcinoma - p. 80 47. 36. Pleomorphic giant cell carcinoma of the prostate - p. 82 48. 37. Lymphoepithelioma-like carcinoma of the prostate - p. 84 49. 38. Prostate carcinoma with squamous differentiation - p. 85 50. 39. Ductal adenocarcinoma - p. 87 51. 40. Prostatic adenocarcinoma with neuroendocrine differentiation - p. 90 52. 41. Well-differentiated neuroendocrine tumor - p. 93 53. 42. Small cell carcinoma, prostate - p. 96 54. 43. Prostatic basal cell adenoma - p. 99 55. 44. Basal cell carcinoma of the prostate - p. 101 56. 45. Squamous neoplasms including squamous cell and adenosquamous carcinoma - p. 103 57. 46. Urothelial carcinoma - p. 104 58. 47. Prostatic stromal tumors of uncertain malignant potential - p. 107 59. 48. Prostatic stromal sarcoma - p. 110 60. 49. Atypical glands suspicious for prostatic carcinoma - p. 112 61. 50. High-grade prostatic intraepithelial neoplasia with adjacent atypical glands - p. 115 62. 51. Radiation-induced changes - p. 117 63. 52. Hormonal ablation-induced changes - p. 120 64. 53. Cryoablation therapy-induced changes - p. 123 65. 54. Immunohistochemical work-up of prostate carcinoma - p. 126 66. 55. Gleason grading of prostate carcinoma - p. 129 67. 56. Prostate cancer staging in radical prostatectomy - p. 133 68. 57. Genetics and genomics in prostate cancer - p. 137 69. 58. Work-up of “vanishing” cancer in radical prostatectomy - p. 139 70. 59. Nonprostatic adenocarcinoma involving the prostate - p. 140 71. C. Seminal Vesicles - p. 142 72. 60. Anatomy and histology of seminal vesicles - p. 142 73. 61. Amyloidosis - p. 146 74. 62. Seminal vesicle adenocarcinoma - p. 148 75. 63. Mixed epithelial and stromal tumor - p. 149 76. D. Nonneoplastic Disease of the Urinary Bladder - p. 152 77. 64. Anatomy and histology of the urinary bladder - p. 152 78. 65. von Brunn nests - p. 155 79. 66. Cystitis cystica et glandularis - p. 156 80. 67. Squamous metaplasia - p. 158 81. 68. Intestinal metaplasia - p. 160 82. 69. Nephrogenic metaplasia/adenoma - p. 162 83. 70. Polypoid and papillary cystitis - p. 165 84. 71. Follicular cystitis - p. 167 85. 72. Giant cell cystitis - p. 168 86. 73. Interstitial cystitis/painful bladder syndrome - p. 169 87. 74. Eosinophilic cystitis - p. 171 88. 75. Infectious cystitis - p. 173 89. 76. Malakoplakia - p. 177 90. 77. Granulomatous cystitis after BCG - p. 179 91. 78. Radiation cystitis - p. 181 92. 79. Chemotherapy-induced cystitis - p. 183 93. 80. Endometriosis of the bladder - p. 185 94. 81. Bladder endocervicosis - p. 188 95. 82. Bladder exstrophy - p. 191 96. 83. Urachal anomaly - p. 192 97. 84. Bladder diverticulum - p. 194 98. 85. Ectopic prostate tissue - p. 196 99. E. Neoplastic Disease of the Urinary Bladder - p. 198 100. 86. Urothelial proliferation of uncertain malignant potential - p. 198 101. 87. Reactive urothelial atypia - p. 201 102. 88. Urothelial atypia of unknown significance - p. 203 103. 89. Urothelial dysplasia - p. 204 104. 90. Urothelial carcinoma in situ - p. 206 105. 91. Urothelial papilloma - p. 208 106. 92. Inverted papilloma - p. 210 107. 93. Papillary urothelial neoplasm of low malignant potential - p. 213 108. 94. Low-grade papillary urothelial carcinoma - p. 215 109. 95. High-grade papillary urothelial carcinoma - p. 217 110. 96. Invasive urothelial carcinoma - p. 219 111. 97. Urothelial carcinoma with inverted growth pattern - p. 222 112. 98. Urothelial carcinoma with squamous differentiation - p. 224 113. 99. Urothelial carcinoma with villoglandular differentiation - p. 225 114. 100. Urothelial carcinoma, plasmacytoid variant - p. 227 115. 101. Urothelial carcinoma, nested variant - p. 230 116. 102. Urothelial carcinoma, micropapillary variant - p. 233 117. 103. Urothelial carcinoma, microcystic variant - p. 236 118. 104. Urothelial carcinoma, lymphoepithelioma-like carcinoma variant - p. 238 119. 105. Urothelial carcinoma, clear cell (glycogen-rich) variant - p. 240 120. 106. Lipid-rich urothelial carcinoma - p. 242 121. 107. Urothelial carcinoma, giant cell variant - p. 243 122. 108. Urothelial carcinoma with syncytiotrophoblastic giant cells - p. 245 123. 109. Urothelial carcinoma with rhabdoid differentiation - p. 248 124. 110. Urothelial carcinoma similar to giant cell tumor of bone - p. 250 125. 111. Undifferentiated urothelial carcinomas - p. 252 126. 112. Small cell carcinoma of the urinary bladder - p. 254 127. 113. Urothelial carcinoma with unusual stromal reactions - p. 256 128. 114. Urothelial carcinoma with sarcomatoid differentiation - p. 257 129. 115. Villous adenoma - p. 260 130. 116. Adenocarcinoma - p. 262 131. 117. Clear cell adenocarcinoma - p. 264 132. 118. Urachal adenocarcinoma - p. 266 133. 119. Squamous cell carcinoma - p. 268 134. 120. Paraganglioma - p. 270 135. 121. Staging of urothelial carcinoma of the urinary bladder and urethra - p. 272 136. 122. Molecular genomics of bladder cancer - p. 274 137. 123. Secondary spread of prostate carcinoma to the bladder - p. 278 138. 124. Secondary adenocarcinoma involving the bladder, other than prostatic carcinoma - p. 280 139. F. Nonneoplastic Disease of the Kidney - p. 284 140. 125. Anatomy of the kidney - p. 284 141. 126. Renal dysplasia - p. 287 142. 127. Localized cystic disease of the kidney - p. 289 143. 128. Autosomal recessive polycystic kidney disease - p. 290 144. 129. Autosomal dominant polycystic kidney disease - p. 292 145. 130. Medullary sponge kidney - p. 295 146. 131. Acquired cystic renal disease - p. 296 147. 132. Simple cortical cyst - p. 298 148. 133. Acute pyelonephritis - p. 299 149. 134. Chronic nonobstructive pyelonephritis - p. 301 150. 135. Chronic obstructive pyelonephritis - p. 303 151. 136. Xanthogranulomatous pyelonephritis - p. 305 152. 137. Renal papillary necrosis - p. 307 153. 138. Benign nephrosclerosis - p. 308 154. 139. Malignant nephrosclerosis - p. 311 155. 140. Acute kidney injury (acute tubular necrosis) - p. 313 156. 141. Acute interstitial nephritis - p. 315 157. 142. Infectious interstitial nephritis - p. 317 158. G. Neoplastic Disease of the Kidney - p. 320 159. 143. Papillary adenoma - p. 320 160. 144. Renal oncocytoma - p. 322 161. 145. Clear cell renal cell carcinoma - p. 325 162. 146. Multilocular cystic renal neoplasm of low malignant potential - p. 328 163. 147. Papillary renal cell carcinoma - p. 330 164. 148. Chromophobe renal cell carcinoma - p. 335 165. 149. Fumarate hydratase-deficient renal cell carcinoma, including hereditary leiomyomatosis and renal cell carcinoma syndrome - p. 337 166. 150. Collecting duct carcinoma - p. 339 167. 151. Renal medullary carcinoma - p. 342 168. 152. Mit family translocation renal cell carcinoma - p. 344 169. 153. Succinate dehydrogenase-deficient renal cell carcinoma - p. 346 170. 154. Mucinous tubular and spindle cell carcinoma - p. 348 171. 155. Tubulocystic carcinoma - p. 350 172. 156. Acquired cystic kidney disease-associated renal cell carcinoma - p. 353 173. 157. Thyroid-like follicular renal cell carcinoma - p. 355 174. 158. Clear cell papillary renal cell carcinoma - p. 357 175. 159. Renal cell carcinoma with fibromyomatous stroma - p. 360 176. 160. Eosinophilic solid cystic renal cell carcinoma - p. 362 177. 161. Renal cell carcinoma with somatic mutations in TSC/mTORC1 genes - p. 364 178. 162. Renal cell carcinoma with sarcomatoid differentiation - p. 367 179. 163. Renal cell carcinoma, unclassified type - p. 370 180. 164. Grading system for renal cell carcinoma - p. 372 181. 165. Staging of renal cell carcinoma - p. 375 182. 166. Renal cell carcinoma in von Hippel-Lindau disease - p. 377 183. 167. Renal cell neoplasms in Birt-Hogg-Dubé (BHD) syndrome - p. 379 184. 168. Renal tumors in tuberous sclerosis complex (TSC) - p. 381 185. 169. Metanephric adenoma - p. 384 186. 170. Metanephric stromal tumor - p. 386 187. 171. Wilms tumor - p. 388 188. 172. Nephrogenic rests and nephroblastomatosis - p. 391 189. 173. Congenital mesoblastic nephroma (CMN) - p. 392 190. 174. Rhabdoid tumor of the kidney - p. 395 191. 175. Clear cell sarcoma of the kidney - p. 397 192. 176. Ossifying renal tumor of infancy - p. 399 193. 177. Renal angiomyolipoma - p. 401 194. 178. Epithelioid angiomyolipoma - p. 405 195. 179. Juxtaglomerular cell tumor - p. 408 196. 180. Renal medullary fibroma (renomedullary interstitial cell tumor) - p. 409 197. 181. Mixed epithelial and stromal tumor family - p. 411 198. 182. Primary renal synovial sarcoma - p. 413 199. 183. Renal carcinoid tumor - p. 415 200. H. Renal Pelvis and Ureter - p. 418 201. 184. Ureteropelvic junction obstruction - p. 418 202. 185. Idiopathic retroperitoneal fibrosis, including IgG4-related disease - p. 421 203. 186. Fibroepithelial polyp of the ureter and renal pelvis - p. 423 204. 187. Ureteral urothelial carcinoma and staging - p. 424 205. 188. Staging for pelvic urothelial carcinoma - p. 425 206. I. Nonneoplastic Disease of the Testis - p. 426 207. 189. Testis: Anatomy and histology - p. 426 208. 190. Cryptorchidism - p. 429 209. 191. Testiculosplenic fusion - p. 432 210. 192. Adrenal cortical rests - p. 434 211. 193. Spermatic cord torsion and testicular infarction - p. 436 212. 194. Testicular microlithiasis - p. 438 213. 195. Vasculitis - p. 440 214. 196. Male infertility workup - p. 442 215. 197. Maturation arrest - p. 444 216. 198. Hypospermatogenesis - p. 445 217. 199. Germ cell aplasia, sertoli cell-only syndrome - p. 447 218. 200. Excurrent duct obstruction - p. 449 219. 201. Pre-pubertal gonadotropin deficiency - p. 450 220. 202. Postpubertal gonadotrophin deficiency - p. 452 221. 203. Viral orchitis - p. 453 222. 204. Granulomatous orchiepididymitis - p. 454 223. 205. Nonspecific granulomatous orchitis - p. 456 224. 206. Androgen insensitivity syndrome - p. 458 225. 207. Klinefelter syndrome - p. 459 226. 208. Testicular tumor of the adrenogenital syndrome - p. 461 227. 209. Embryonic testicular regression (Vanishing testis syndrome) - p. 464 228. 210. Gonadal dysgenesis - p. 466 229. J. Neoplastic Disease of the Testis - p. 468 230. 211. Germ cell neoplasia in situ - p. 468 231. 212. Specific forms of intratubular germ cell neoplasia - p. 471 232. 213. Seminoma - p. 472 233. 214. Embryonal carcinoma - p. 476 234. 215. Postpubertal-type yolk sac tumor - p. 479 235. 216. Postpubertal-type teratoma - p. 482 236. 217. Mixed germ cell tumor - p. 484 237. 218. Teratoma with somatic-type malignancies - p. 486 238. 219. Choriocarcinoma - p. 488 239. 220. Non-choriocarcinomatous trophoblastic tumors - p. 490 240. 221. Regressed germ cell tumors - p. 491 241. 222. Spermatocytic tumor - p. 493 242. 223. Prepubertal-type teratoma, testicular carcinoid tumor - p. 495 243. 224. Teratoma, prepubertal-type, dermoid cyst - p. 497 244. 225. Prepubertal teratoma, epidermoid cyst - p. 499 245. 226. Yolk sac tumor, prepubertal type - p. 500 246. 227. Leydig cell tumor - p. 501 247. 228. Sertoli cell tumor - p. 504 248. 229. Sclerosing sertoli cell tumor - p. 507 249. 230. Large cell calcifying sertoli cell tumor - p. 509 250. 231. Adult granulosa cell tumor - p. 511 251. 232. Juvenile granulosa cell tumor - p. 513 252. 233. Fibrothecoma - p. 515 253. 234. Stromal tumor of the testis, mixed and unclassified type - p. 517 254. 235. Myoid gonadal stromal tumor - p. 519 255. 236. Gonadoblastoma - p. 521 256. 237. Testicular lymphoma - p. 523 257. 238. Ovarian epithelial-type testicular tumors - p. 525 258. 239. Tumors of the rete testis - p. 529 259. 240. Testicular cancer staging - p. 532 260. K. Spermatic Cord and Testicular Adnexa - p. 534 261. 241. Appendix testis - p. 534 262. 242. Appendix epididymis - p. 537 263. 243. Glandular inclusions in inguinal herniorrhaphy specimens - p. 538 264. 244. Hydrocele - p. 540 265. 245. Spermatocele - p. 542 266. 246. Vasitis nodosa - p. 544 267. 247. Sperm granuloma - p. 546 268. 248. Adenomatoid tumor - p. 548 269. 249. Fibrous pseudotumor - p. 550 270. 250. Paratesticular idiopathic smooth muscle hyperplasia - p. 552 271. 251. Papillary cystadenoma of the epididymis - p. 553 272. 252. Paratesticular lipoma - p. 554 273. 253. Paratesticular liposarcoma - p. 555 274. 254. Paratesticular rhabdomyosarcoma - p. 557 275. 255. Leiomyoma of the spermatic cord and testicular adnexa - p. 559 276. 256. Paratesticular leiomyosarcoma - p. 561 277. 257. Aggressive angiomyxoma of the male genital region - p. 562 278. 258. Cellular angiofibroma - p. 564 279. 259. Malignant mesothelioma, paratesticular - p. 566 280. 260. Epithelial tumors of the rete testis - p. 568 281. L. Disease of the Penis, Urethra, and Scrotum - p. 570 282. 261. Fibroepithelial polyp of the urethra - p. 570 283. 262. Urethral caruncle - p. 573 284. 263. Urethral diverticulum - p. 575 285. 264. Urethral stricture - p. 577 286. 265. Polypoid urethritis - p. 578 287. 266. Condyloma acuminatum - p. 579 288. 267. Prostatic-type urethral polyp - p. 581 289. 268. Urethral urothelial carcinoma associated with bladder urothelial carcinoma - p. 583 290. 269. Primary urethral carcinoma - p. 585 291. 270. Urethral adenocarcinoma - p. 587 292. 271. Clear cell adenocarcinoma of the urethra - p. 589 293. 272. Zoon balanitis - p. 591 294. 273. Lichen sclerosus et atrophicus (balanitis xerotica obliterans) - p. 592 295. 274. Pseudoepitheliomatous keratotic micaceous balanitis - p. 594 296. 275. Peyronie disease - p. 596 297. 276. Squamous hyperplasia of the penis - p. 597 298. 277. Penile intraepithelial neoplasia (PeIN) - p. 598 299. 278. Differentiated penile intraepithelial neoplasia - p. 600 300. 279. Squamous cell carcinoma of the penis, usual type - p. 602 301. 280. Basaloid squamous cell carcinoma - p. 604 302. 281. Squamous cell carcinoma, papillary-basaloid - p. 606 303. 282. Penile warty (condylomatous) carcinoma - p. 608 304. 283. Squamous cell carcinoma, warty-basaloid - p. 610 305. 284. Clear cell squamous cell carcinoma - p. 612 306. 285. Lymphoepithelioma-like carcinoma - p. 614 307. 286. Squamous cell carcinoma, verrucous - p. 615 308. 287. Squamous cell carcinoma, papillary - p. 617 309. 288. Squamous cell carcinoma, pseudohyperplastic variant - p. 619 310. 289. Squamous cell carcinoma, pseudoglandular - p. 621 311. 290. Squamous cell carcinoma, cuniculatum - p. 623 312. 291. Sarcomatoid (spindle cell) squamous cell carcinoma of the penis - p. 625 313. 292. Adenosquamous carcinoma of the penis - p. 627 314. 293. Mixed squamous cell carcinoma of the penis - p. 628 315. 294. Penile basal cell carcinoma - p. 630 316. 295. Extramammary Paget disease of the penis and scrotum - p. 631 317. 296. Merkel cell carcinoma of the genitourinary tract - p. 634 318. 297. Sclerosing lipogranuloma - p. 636 319. 298. Idiopathic scrotal calcinosis - p. 638 320. 299. Genital melanosis and lentiginosis - p. 640 321. 300. Mucosal melanoma of the genitourinary system - p. 641 322. 301. Staging for penile squamous cell carcinoma - p. 643 323. 302. Staging for urethral carcinoma - p. 644 324. M. Soft Tissue Tumors - p. 646 325. 303. Inflammatory myofibroblastic tumor of the bladder - p. 646 326. 304. Leiomyoma of the bladder - p. 649 327. 305. Leiomyosarcoma of the bladder - p. 650 328. 306. Solitary fibrous tumor - p. 652 329. 307. Gastrointestinal stromal tumor of the genitourinary tract - p. 654 330. 308. Lymphomas of the genitourinary organs - p. 656 331. Index - p. 661
Uropathology
1. Cover image - p. cover 2. Title page - p. ii 3. Table of Contents - p. iii 4. Copyright - p. iii 5. Dedication - p. v 6. Contributors - p. vi 7. Preface - p. vii 8. List of Tables - p. vii 9. List of Illustrations - p. vii 10. A. Nonneoplastic Disease of the Prostate - p. vii 11. 1. Anatomy and histology of the prostate - p. vii 12. 2. Seminal vesicle/ejaculatory duct - p. 6 13. 3. Cowper gland - p. 9 14. 4. Benign prostatic hyperplasia - p. 11 15. 5. Acute inflammation of the prostate - p. 14 16. 6. Chronic inflammation of the prostate - p. 16 17. 7. Nonspecific granulomatous prostatitis - p. 18 18. 8. Post-biopsy granuloma - p. 20 19. 9. Prostatic xanthoma - p. 21 20. 10. Granulomatous prostatitis of infectious etiology - p. 22 21. 11. Simple atrophy - p. 24 22. 12. Cystic atrophy - p. 25 23. 13. Postatrophy hyperplasia - p. 26 24. 14. Partial atrophy - p. 28 25. 15. Adenosis - p. 30 26. 16. Sclerosing adenosis - p. 32 27. 17. Clear cell cribriform hyperplasia - p. 35 28. 18. Hyperplasia of mesonephric remnants - p. 37 29. 19. Basal cell hyperplasia - p. 39 30. 20. Urothelial metaplasia - p. 42 31. 21. Squamous metaplasia - p. 43 32. 22. Mucin cell metaplasia - p. 44 33. 23. Neuroendocrine cells involving the prostate - p. 45 34. 24. Verumontanum mucosal gland hyperplasia - p. 47 35. 25. Prostatic infarct - p. 48 36. B. Neoplastic Disease of the Prostate - p. 50 37. 26. High-grade prostatic intraepithelial neoplasia (HGPIN) - p. 50 38. 27. Intraductal carcinoma of the prostate - p. 55 39. 28. Prostatic carcinoma, usual variant - p. 58 40. 29. Prostatic carcinoma, atrophic variant - p. 65 41. 30. Prostatic carcinoma, foamy gland variant - p. 67 42. 31. Prostatic carcinoma, pseudohyperplastic variant - p. 69 43. 32. Prostatic carcinoma, mucinous variant - p. 72 44. 33. Prostatic carcinoma, microcystic variant - p. 74 45. 34. Prostatic intraepithelial neoplasia (PIN)-like adenocarcinoma - p. 77 46. 35. Sarcomatoid carcinoma - p. 80 47. 36. Pleomorphic giant cell carcinoma of the prostate - p. 82 48. 37. Lymphoepithelioma-like carcinoma of the prostate - p. 84 49. 38. Prostate carcinoma with squamous differentiation - p. 85 50. 39. Ductal adenocarcinoma - p. 87 51. 40. Prostatic adenocarcinoma with neuroendocrine differentiation - p. 90 52. 41. Well-differentiated neuroendocrine tumor - p. 93 53. 42. Small cell carcinoma, prostate - p. 96 54. 43. Prostatic basal cell adenoma - p. 99 55. 44. Basal cell carcinoma of the prostate - p. 101 56. 45. Squamous neoplasms including squamous cell and adenosquamous carcinoma - p. 103 57. 46. Urothelial carcinoma - p. 104 58. 47. Prostatic stromal tumors of uncertain malignant potential - p. 107 59. 48. Prostatic stromal sarcoma - p. 110 60. 49. Atypical glands suspicious for prostatic carcinoma - p. 112 61. 50. High-grade prostatic intraepithelial neoplasia with adjacent atypical glands - p. 115 62. 51. Radiation-induced changes - p. 117 63. 52. Hormonal ablation-induced changes - p. 120 64. 53. Cryoablation therapy-induced changes - p. 123 65. 54. Immunohistochemical work-up of prostate carcinoma - p. 126 66. 55. Gleason grading of prostate carcinoma - p. 129 67. 56. Prostate cancer staging in radical prostatectomy - p. 133 68. 57. Genetics and genomics in prostate cancer - p. 137 69. 58. Work-up of “vanishing” cancer in radical prostatectomy - p. 139 70. 59. Nonprostatic adenocarcinoma involving the prostate - p. 140 71. C. Seminal Vesicles - p. 142 72. 60. Anatomy and histology of seminal vesicles - p. 142 73. 61. Amyloidosis - p. 146 74. 62. Seminal vesicle adenocarcinoma - p. 148 75. 63. Mixed epithelial and stromal tumor - p. 149 76. D. Nonneoplastic Disease of the Urinary Bladder - p. 152 77. 64. Anatomy and histology of the urinary bladder - p. 152 78. 65. von Brunn nests - p. 155 79. 66. Cystitis cystica et glandularis - p. 156 80. 67. Squamous metaplasia - p. 158 81. 68. Intestinal metaplasia - p. 160 82. 69. Nephrogenic metaplasia/adenoma - p. 162 83. 70. Polypoid and papillary cystitis - p. 165 84. 71. Follicular cystitis - p. 167 85. 72. Giant cell cystitis - p. 168 86. 73. Interstitial cystitis/painful bladder syndrome - p. 169 87. 74. Eosinophilic cystitis - p. 171 88. 75. Infectious cystitis - p. 173 89. 76. Malakoplakia - p. 177 90. 77. Granulomatous cystitis after BCG - p. 179 91. 78. Radiation cystitis - p. 181 92. 79. Chemotherapy-induced cystitis - p. 183 93. 80. Endometriosis of the bladder - p. 185 94. 81. Bladder endocervicosis - p. 188 95. 82. Bladder exstrophy - p. 191 96. 83. Urachal anomaly - p. 192 97. 84. Bladder diverticulum - p. 194 98. 85. Ectopic prostate tissue - p. 196 99. E. Neoplastic Disease of the Urinary Bladder - p. 198 100. 86. Urothelial proliferation of uncertain malignant potential - p. 198 101. 87. Reactive urothelial atypia - p. 201 102. 88. Urothelial atypia of unknown significance - p. 203 103. 89. Urothelial dysplasia - p. 204 104. 90. Urothelial carcinoma in situ - p. 206 105. 91. Urothelial papilloma - p. 208 106. 92. Inverted papilloma - p. 210 107. 93. Papillary urothelial neoplasm of low malignant potential - p. 213 108. 94. Low-grade papillary urothelial carcinoma - p. 215 109. 95. High-grade papillary urothelial carcinoma - p. 217 110. 96. Invasive urothelial carcinoma - p. 219 111. 97. Urothelial carcinoma with inverted growth pattern - p. 222 112. 98. Urothelial carcinoma with squamous differentiation - p. 224 113. 99. Urothelial carcinoma with villoglandular differentiation - p. 225 114. 100. Urothelial carcinoma, plasmacytoid variant - p. 227 115. 101. Urothelial carcinoma, nested variant - p. 230 116. 102. Urothelial carcinoma, micropapillary variant - p. 233 117. 103. Urothelial carcinoma, microcystic variant - p. 236 118. 104. Urothelial carcinoma, lymphoepithelioma-like carcinoma variant - p. 238 119. 105. Urothelial carcinoma, clear cell (glycogen-rich) variant - p. 240 120. 106. Lipid-rich urothelial carcinoma - p. 242 121. 107. Urothelial carcinoma, giant cell variant - p. 243 122. 108. Urothelial carcinoma with syncytiotrophoblastic giant cells - p. 245 123. 109. Urothelial carcinoma with rhabdoid differentiation - p. 248 124. 110. Urothelial carcinoma similar to giant cell tumor of bone - p. 250 125. 111. Undifferentiated urothelial carcinomas - p. 252 126. 112. Small cell carcinoma of the urinary bladder - p. 254 127. 113. Urothelial carcinoma with unusual stromal reactions - p. 256 128. 114. Urothelial carcinoma with sarcomatoid differentiation - p. 257 129. 115. Villous adenoma - p. 260 130. 116. Adenocarcinoma - p. 262 131. 117. Clear cell adenocarcinoma - p. 264 132. 118. Urachal adenocarcinoma - p. 266 133. 119. Squamous cell carcinoma - p. 268 134. 120. Paraganglioma - p. 270 135. 121. Staging of urothelial carcinoma of the urinary bladder and urethra - p. 272 136. 122. Molecular genomics of bladder cancer - p. 274 137. 123. Secondary spread of prostate carcinoma to the bladder - p. 278 138. 124. Secondary adenocarcinoma involving the bladder, other than prostatic carcinoma - p. 280 139. F. Nonneoplastic Disease of the Kidney - p. 284 140. 125. Anatomy of the kidney - p. 284 141. 126. Renal dysplasia - p. 287 142. 127. Localized cystic disease of the kidney - p. 289 143. 128. Autosomal recessive polycystic kidney disease - p. 290 144. 129. Autosomal dominant polycystic kidney disease - p. 292 145. 130. Medullary sponge kidney - p. 295 146. 131. Acquired cystic renal disease - p. 296 147. 132. Simple cortical cyst - p. 298 148. 133. Acute pyelonephritis - p. 299 149. 134. Chronic nonobstructive pyelonephritis - p. 301 150. 135. Chronic obstructive pyelonephritis - p. 303 151. 136. Xanthogranulomatous pyelonephritis - p. 305 152. 137. Renal papillary necrosis - p. 307 153. 138. Benign nephrosclerosis - p. 308 154. 139. Malignant nephrosclerosis - p. 311 155. 140. Acute kidney injury (acute tubular necrosis) - p. 313 156. 141. Acute interstitial nephritis - p. 315 157. 142. Infectious interstitial nephritis - p. 317 158. G. Neoplastic Disease of the Kidney - p. 320 159. 143. Papillary adenoma - p. 320 160. 144. Renal oncocytoma - p. 322 161. 145. Clear cell renal cell carcinoma - p. 325 162. 146. Multilocular cystic renal neoplasm of low malignant potential - p. 328 163. 147. Papillary renal cell carcinoma - p. 330 164. 148. Chromophobe renal cell carcinoma - p. 335 165. 149. Fumarate hydratase-deficient renal cell carcinoma, including hereditary leiomyomatosis and renal cell carcinoma syndrome - p. 337 166. 150. Collecting duct carcinoma - p. 339 167. 151. Renal medullary carcinoma - p. 342 168. 152. Mit family translocation renal cell carcinoma - p. 344 169. 153. Succinate dehydrogenase-deficient renal cell carcinoma - p. 346 170. 154. Mucinous tubular and spindle cell carcinoma - p. 348 171. 155. Tubulocystic carcinoma - p. 350 172. 156. Acquired cystic kidney disease-associated renal cell carcinoma - p. 353 173. 157. Thyroid-like follicular renal cell carcinoma - p. 355 174. 158. Clear cell papillary renal cell carcinoma - p. 357 175. 159. Renal cell carcinoma with fibromyomatous stroma - p. 360 176. 160. Eosinophilic solid cystic renal cell carcinoma - p. 362 177. 161. Renal cell carcinoma with somatic mutations in TSC/mTORC1 genes - p. 364 178. 162. Renal cell carcinoma with sarcomatoid differentiation - p. 367 179. 163. Renal cell carcinoma, unclassified type - p. 370 180. 164. Grading system for renal cell carcinoma - p. 372 181. 165. Staging of renal cell carcinoma - p. 375 182. 166. Renal cell carcinoma in von Hippel-Lindau disease - p. 377 183. 167. Renal cell neoplasms in Birt-Hogg-Dubé (BHD) syndrome - p. 379 184. 168. Renal tumors in tuberous sclerosis complex (TSC) - p. 381 185. 169. Metanephric adenoma - p. 384 186. 170. Metanephric stromal tumor - p. 386 187. 171. Wilms tumor - p. 388 188. 172. Nephrogenic rests and nephroblastomatosis - p. 391 189. 173. Congenital mesoblastic nephroma (CMN) - p. 392 190. 174. Rhabdoid tumor of the kidney - p. 395 191. 175. Clear cell sarcoma of the kidney - p. 397 192. 176. Ossifying renal tumor of infancy - p. 399 193. 177. Renal angiomyolipoma - p. 401 194. 178. Epithelioid angiomyolipoma - p. 405 195. 179. Juxtaglomerular cell tumor - p. 408 196. 180. Renal medullary fibroma (renomedullary interstitial cell tumor) - p. 409 197. 181. Mixed epithelial and stromal tumor family - p. 411 198. 182. Primary renal synovial sarcoma - p. 413 199. 183. Renal carcinoid tumor - p. 415 200. H. Renal Pelvis and Ureter - p. 418 201. 184. Ureteropelvic junction obstruction - p. 418 202. 185. Idiopathic retroperitoneal fibrosis, including IgG4-related disease - p. 421 203. 186. Fibroepithelial polyp of the ureter and renal pelvis - p. 423 204. 187. Ureteral urothelial carcinoma and staging - p. 424 205. 188. Staging for pelvic urothelial carcinoma - p. 425 206. I. Nonneoplastic Disease of the Testis - p. 426 207. 189. Testis: Anatomy and histology - p. 426 208. 190. Cryptorchidism - p. 429 209. 191. Testiculosplenic fusion - p. 432 210. 192. Adrenal cortical rests - p. 434 211. 193. Spermatic cord torsion and testicular infarction - p. 436 212. 194. Testicular microlithiasis - p. 438 213. 195. Vasculitis - p. 440 214. 196. Male infertility workup - p. 442 215. 197. Maturation arrest - p. 444 216. 198. Hypospermatogenesis - p. 445 217. 199. Germ cell aplasia, sertoli cell-only syndrome - p. 447 218. 200. Excurrent duct obstruction - p. 449 219. 201. Pre-pubertal gonadotropin deficiency - p. 450 220. 202. Postpubertal gonadotrophin deficiency - p. 452 221. 203. Viral orchitis - p. 453 222. 204. Granulomatous orchiepididymitis - p. 454 223. 205. Nonspecific granulomatous orchitis - p. 456 224. 206. Androgen insensitivity syndrome - p. 458 225. 207. Klinefelter syndrome - p. 459 226. 208. Testicular tumor of the adrenogenital syndrome - p. 461 227. 209. Embryonic testicular regression (Vanishing testis syndrome) - p. 464 228. 210. Gonadal dysgenesis - p. 466 229. J. Neoplastic Disease of the Testis - p. 468 230. 211. Germ cell neoplasia in situ - p. 468 231. 212. Specific forms of intratubular germ cell neoplasia - p. 471 232. 213. Seminoma - p. 472 233. 214. Embryonal carcinoma - p. 476 234. 215. Postpubertal-type yolk sac tumor - p. 479 235. 216. Postpubertal-type teratoma - p. 482 236. 217. Mixed germ cell tumor - p. 484 237. 218. Teratoma with somatic-type malignancies - p. 486 238. 219. Choriocarcinoma - p. 488 239. 220. Non-choriocarcinomatous trophoblastic tumors - p. 490 240. 221. Regressed germ cell tumors - p. 491 241. 222. Spermatocytic tumor - p. 493 242. 223. Prepubertal-type teratoma, testicular carcinoid tumor - p. 495 243. 224. Teratoma, prepubertal-type, dermoid cyst - p. 497 244. 225. Prepubertal teratoma, epidermoid cyst - p. 499 245. 226. Yolk sac tumor, prepubertal type - p. 500 246. 227. Leydig cell tumor - p. 501 247. 228. Sertoli cell tumor - p. 504 248. 229. Sclerosing sertoli cell tumor - p. 507 249. 230. Large cell calcifying sertoli cell tumor - p. 509 250. 231. Adult granulosa cell tumor - p. 511 251. 232. Juvenile granulosa cell tumor - p. 513 252. 233. Fibrothecoma - p. 515 253. 234. Stromal tumor of the testis, mixed and unclassified type - p. 517 254. 235. Myoid gonadal stromal tumor - p. 519 255. 236. Gonadoblastoma - p. 521 256. 237. Testicular lymphoma - p. 523 257. 238. Ovarian epithelial-type testicular tumors - p. 525 258. 239. Tumors of the rete testis - p. 529 259. 240. Testicular cancer staging - p. 532 260. K. Spermatic Cord and Testicular Adnexa - p. 534 261. 241. Appendix testis - p. 534 262. 242. Appendix epididymis - p. 537 263. 243. Glandular inclusions in inguinal herniorrhaphy specimens - p. 538 264. 244. Hydrocele - p. 540 265. 245. Spermatocele - p. 542 266. 246. Vasitis nodosa - p. 544 267. 247. Sperm granuloma - p. 546 268. 248. Adenomatoid tumor - p. 548 269. 249. Fibrous pseudotumor - p. 550 270. 250. Paratesticular idiopathic smooth muscle hyperplasia - p. 552 271. 251. Papillary cystadenoma of the epididymis - p. 553 272. 252. Paratesticular lipoma - p. 554 273. 253. Paratesticular liposarcoma - p. 555 274. 254. Paratesticular rhabdomyosarcoma - p. 557 275. 255. Leiomyoma of the spermatic cord and testicular adnexa - p. 559 276. 256. Paratesticular leiomyosarcoma - p. 561 277. 257. Aggressive angiomyxoma of the male genital region - p. 562 278. 258. Cellular angiofibroma - p. 564 279. 259. Malignant mesothelioma, paratesticular - p. 566 280. 260. Epithelial tumors of the rete testis - p. 568 281. L. Disease of the Penis, Urethra, and Scrotum - p. 570 282. 261. Fibroepithelial polyp of the urethra - p. 570 283. 262. Urethral caruncle - p. 573 284. 263. Urethral diverticulum - p. 575 285. 264. Urethral stricture - p. 577 286. 265. Polypoid urethritis - p. 578 287. 266. Condyloma acuminatum - p. 579 288. 267. Prostatic-type urethral polyp - p. 581 289. 268. Urethral urothelial carcinoma associated with bladder urothelial carcinoma - p. 583 290. 269. Primary urethral carcinoma - p. 585 291. 270. Urethral adenocarcinoma - p. 587 292. 271. Clear cell adenocarcinoma of the urethra - p. 589 293. 272. Zoon balanitis - p. 591 294. 273. Lichen sclerosus et atrophicus (balanitis xerotica obliterans) - p. 592 295. 274. Pseudoepitheliomatous keratotic micaceous balanitis - p. 594 296. 275. Peyronie disease - p. 596 297. 276. Squamous hyperplasia of the penis - p. 597 298. 277. Penile intraepithelial neoplasia (PeIN) - p. 598 299. 278. Differentiated penile intraepithelial neoplasia - p. 600 300. 279. Squamous cell carcinoma of the penis, usual type - p. 602 301. 280. Basaloid squamous cell carcinoma - p. 604 302. 281. Squamous cell carcinoma, papillary-basaloid - p. 606 303. 282. Penile warty (condylomatous) carcinoma - p. 608 304. 283. Squamous cell carcinoma, warty-basaloid - p. 610 305. 284. Clear cell squamous cell carcinoma - p. 612 306. 285. Lymphoepithelioma-like carcinoma - p. 614 307. 286. Squamous cell carcinoma, verrucous - p. 615 308. 287. Squamous cell carcinoma, papillary - p. 617 309. 288. Squamous cell carcinoma, pseudohyperplastic variant - p. 619 310. 289. Squamous cell carcinoma, pseudoglandular - p. 621 311. 290. Squamous cell carcinoma, cuniculatum - p. 623 312. 291. Sarcomatoid (spindle cell) squamous cell carcinoma of the penis - p. 625 313. 292. Adenosquamous carcinoma of the penis - p. 627 314. 293. Mixed squamous cell carcinoma of the penis - p. 628 315. 294. Penile basal cell carcinoma - p. 630 316. 295. Extramammary Paget disease of the penis and scrotum - p. 631 317. 296. Merkel cell carcinoma of the genitourinary tract - p. 634 318. 297. Sclerosing lipogranuloma - p. 636 319. 298. Idiopathic scrotal calcinosis - p. 638 320. 299. Genital melanosis and lentiginosis - p. 640 321. 300. Mucosal melanoma of the genitourinary system - p. 641 322. 301. Staging for penile squamous cell carcinoma - p. 643 323. 302. Staging for urethral carcinoma - p. 644 324. M. Soft Tissue Tumors - p. 646 325. 303. Inflammatory myofibroblastic tumor of the bladder - p. 646 326. 304. Leiomyoma of the bladder - p. 649 327. 305. Leiomyosarcoma of the bladder - p. 650 328. 306. Solitary fibrous tumor - p. 652 329. 307. Gastrointestinal stromal tumor of the genitourinary tract - p. 654 330. 308. Lymphomas of the genitourinary organs - p. 656 331. Index - p. 661
